Patents by Inventor Yuri Furusawa

Yuri Furusawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECOMBINANT INFLUENZA VIRUSES WITH STABILIZED NA
    Publication number: 20240010995
    Abstract: Modified influenza virus neuraminidases are described herein that have stabilized NA tetramers which may improve vaccine production efficiency, thus improving the yield of vaccine viruses.
    Type: Application
    Filed: August 3, 2023
    Publication date: January 11, 2024
    Inventors: Yoshihiro Kawaoka, Yuri Furusawa, Seiya Yamayoshi
  • Recombinant influenza viruses with stabilized NA
    Patent number: 11739303
    Abstract: Modified influenza virus neuraminidases are described herein that have stabilized NA tetramers which may improve vaccine production efficiency, thus improving the yield of vaccine viruses.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: August 29, 2023
    Assignees: Wisconsin Alumni Research Foundation (WARF), The University of Tokyo
    Inventors: Yoshihiro Kawaoka, Yuri Furusawa, Seiya Yamayoshi
  • MUTATIONS THAT CONFER GENETIC STABILITY TO GENES IN INFLUENZA VIRUSES
    Publication number: 20220241396
    Abstract: The disclosure provides for an isolated recombinant influenza virus having at least one of: a PB2 viral segment encoding PB2 with residue at position 540 that is not asparagine or a residue at position 712 that is not glutamic acid, a PA viral segment encoding PA with a residue at position 180 that is not glutamine or a residue at position 200 that is not threonine, or a PB1 viral segment encoding PB1 with a residue at position 149 that is not valine, a residue at position 634 that is not glutamic acid or a residue at position 635 that is not aspartic acid, or any combination thereof, and methods of making and using the virus.
    Type: Application
    Filed: January 19, 2022
    Publication date: August 4, 2022
    Inventors: Yoshihiro Kawaoka, Yuri Furusawa
  • Mutations that confer genetic stability to genes in influenza viruses
    Patent number: 11241492
    Abstract: The disclosure provides for an isolated recombinant influenza virus having at least one of: a PB2 viral segment encoding PB2 with residue at position 540 that is not asparagine or a residue at position 712 that is not glutamic acid, a PA viral segment encoding PA with a residue at position 180 that is not glutamine or a residue at position 200 that is not threonine, or a PB1 viral segment encoding PB1 with a residue at position 149 that is not valine, a residue at position 684 that is not glutamic acid or a residue at position 685 that is not aspartic acid, or any combination thereof, and methods of making and using the virus.
    Type: Grant
    Filed: January 22, 2020
    Date of Patent: February 8, 2022
    Assignee: Wisconsin Alumni Research Foundation (WARF)
    Inventors: Yoshihiro Kawaoka, Yuri Furusawa
  • RECOMBINANT INFLUENZA VIRUSES WITH STABILIZED NA
    Publication number: 20210246432
    Abstract: Modified influenza virus neuraminidases are described herein that have stabilized NA tetramers which may improve vaccine production efficiency, thus improving the yield of vaccine viruses.
    Type: Application
    Filed: January 22, 2021
    Publication date: August 12, 2021
    Inventors: Yoshihiro Kawaoka, Yuri Furusawa, Seiya Yamayoshi
  • MUTATIONS THAT CONFER GENETIC STABILITY TO ADDITIONAL GENES IN INFLUENZA VIRUSES
    Publication number: 20200237899
    Abstract: The disclosure provides for an isolated recombinant influenza virus having at least one of: a PB2 viral segment encoding PB2 with residue at position 540 that is not asparagine or a residue at position 712 that is not glutamic acid, a PA viral segment encoding PA with a residue at position 180 that is not glutamine or a residue at position 200 that is not threonine, or a PB1 viral segment encoding PB1 with a residue at position 149 that is not valine, a residue at position 684 that is not glutamic acid or a residue at position 685 that is not aspartic acid, or any combination thereof, and methods of making and using the virus.
    Type: Application
    Filed: January 22, 2020
    Publication date: July 30, 2020
    Inventors: Yoshihiro Kawaoka, Yuri Furusawa