Patents by Inventor Yuri Khmelnitsky

Yuri Khmelnitsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclosporins
    Patent number: 7538084
    Abstract: The compounds of the present invention are represented by the chemical structure found in Formula I: Formula I where A is an amino acid of Formula II: or a pharmaceutically acceptable salt thereof, with R0, R1, B, C, D, E, F, G, H, I, J, and K defined herein.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: May 26, 2009
    Assignee: AMR Technology, Inc.
    Inventors: Bruce F. Molino, Simon N. Haydar, Zhicai Yang, Peter C. Michels, Michael S. Hemenway, Joseph O. Rich, Yuri Khmelnitsky
  • Novel cyclosporins
    Publication number: 20040235716
    Abstract: The compounds of the present invention are represented by the chemical structure found in Formula I: 1 Formula I 1
    Type: Application
    Filed: March 16, 2004
    Publication date: November 25, 2004
    Inventors: Bruce F. Molino, Simon N. Haydar, Zhicai Yang, Peter C. Michels, Michael S. Hemenway, Joseph O. Rich, Yuri Khmelnitsky
  • Reacting an enzyme in a non-aqueous solvent by adding a lyophilizate of enzyme and salt to the solvent
    Patent number: 5449613
    Abstract: A method for reacting an enzyme in a non-aqueous organic solvent is disclosed. The method comprises preparing a lyophilizate of a salt which activates the enzyme and an enzyme wherein the lyophilizate contains a weight ratio of salt to enzyme of at least 60% salt sufficient to activate the enzyme in an organic solvent. The method then calls for dispersion of the lyophilizate in a non-aqueous organic solvent in the presence of a substrate for the enzyme.
    Type: Grant
    Filed: March 1, 1994
    Date of Patent: September 12, 1995
    Assignee: The University of Iowa Research Foundation
    Inventors: Jonathan S. Dordick, Yuri Khmelnitsky, Douglas S. Clark