Patents by Inventor Yuriko Tokura

Yuriko Tokura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heparan sulfate having high 3-O-sulfation rate in glucosamine residues
    Patent number: 10889656
    Abstract: The present invention provides a novel sulfated polysaccharide having anticoagulant activity. Specifically, the present invention provides a polysaccharide that includes a repetitive structure of a disaccharide unit composed of a hexuronic acid (HexA) residue and a ?-D-glucosamine (GlcN) residue and having 13% or higher of a 3-O-sulfation rate in GlcN residues.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: January 12, 2021
    Assignee: AJINOMOTO CO., INC.
    Inventors: Kenichi Mori, Yuriko Tokura, Shunsuke Yamazaki, Tomoko Shimizu, Yasuhiro Mihara
  • Method of producing heparan sulfate having anticoagulant activity
    Patent number: 10704068
    Abstract: The present invention provides a method of producing a heparan sulfate having an anticoagulant activity. Specifically, the present invention provides the method of producing a heparan sulfate having a desired molecular weight, by partially N-deacetylating a heparosan followed by depolymerizing the heparosan by heparinase III, and converting the produced low molecular weight product into heparan sulfate having an anticoagulant activity.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: July 7, 2020
    Assignee: AJINOMOTO CO., INC.
    Inventor: Yuriko Tokura
  • Heparan Sulfate Having High 3-O-Sulfation Rate in Glucosamine Residues
    Publication number: 20180298117
    Abstract: The present invention provides a novel sulfated polysaccharide having anticoagulant activity. Specifically, the present invention provides a polysaccharide that includes a repetitive structure of a disaccharide unit composed of a hexuronic acid (HexA) residue and a ?-D-glucosamine (GlcN) residue and having 13% or higher of a 3-O-sulfation rate in GlcN residues.
    Type: Application
    Filed: June 26, 2018
    Publication date: October 18, 2018
    Applicant: AJINOMOTO CO., INC.
    Inventors: Kenichi Mori, Yuriko Tokura, Shunsuke Yamazaki, Tomoko Shimizu, Yasuhiro Mihara
  • Method of Producing Heparan Sulfate Having Anticoagulant Activity
    Publication number: 20180298411
    Abstract: The present invention provides a method of producing a heparan sulfate having an anticoagulant activity. Specifically, the present invention provides the method of producing a heparan sulfate having a desired molecular weight, by partially N-deacetylating a heparosan followed by depolymerizing the heparosan by heparinase III, and converting the produced low molecular weight product into heparan sulfate having an anticoagulant activity.
    Type: Application
    Filed: June 26, 2018
    Publication date: October 18, 2018
    Applicant: AJINOMOTO CO., INC.
    Inventor: Yuriko Tokura