Abstract: A nano-fluidic device includes: a first substrate that has a nanoscale groove on one surface; and a second substrate that is integrally provided with the first substrate by bonding one surface of the second substrate to the one surface of the first substrate and forms a nanochannel with the groove of the first substrate, in which either the first substrate or the second substrate includes at least a thin portion in a part of a position overlapping the nanochannel in plan view, and the thin portion is deformed by pressing to open and close the nanochannel.

Abstract: A first proton-donating layer (20a) is a layer having a proton-donative functional group on the surface, for example, a silicon oxide layer. A second proton-donating layer (20b) is also a layer having a proton-donative functional group on the surface, for example, a silicon oxide layer. Negative surface charges are formed on the main surface section of a first base (10a) and the main surface section of a second base (10b), and these negative charges increased the proton conductivity in an aqueous solution fed to a nano channel. Although, in the aqueous solution, proton migration through hopping between water molecules contributes to its diffusion, the negative charges formed on the main surfaces of the bases (10a, 10b) attract protons in the aqueous solution, and the conduction of protons is efficiently achieved in “high-speed transfer regions” formed in the vicinity of the proton-donating layers (20a, 20b).

Abstract: A nano-fluidic device includes: a first substrate that has a nanoscale groove on one surface; and a second substrate that is integrally provided with the first substrate by bonding one surface of the second substrate to the one surface of the first substrate and forms a nanochannel with the groove of the first substrate, in which either the first substrate or the second substrate includes at least a thin portion in a part of a position overlapping the nanochannel in plan view, and the thin portion is deformed by pressing to open and close the nanochannel.

Abstract: A first proton-donating layer (20a) is a layer having a proton-donative functional group on the surface, for example, a silicon oxide layer. A second proton-donating layer (20b) is also a layer having a proton-donative functional group on the surface, for example, a silicon oxide layer. Negative surface charges are formed on the main surface section of a first base (10a) and the main surface section of a second base (10b), and these negative charges increased the proton conductivity in an aqueous solution fed to a nano channel. Although, in the aqueous solution, proton migration through hopping between water molecules contributes to its diffusion, the negative charges formed on the main surfaces of the bases (10a, 10b) attract protons in the aqueous solution, and the conduction of protons is efficiently achieved in “high-speed transfer regions” formed in the vicinity of the proton-donating layers (20a, 20b).