Abstract: A pharmaceutical composition for anti-viral treatment for papillomavirus associated diseases in mammals, comprising a therapeutically effective amount of Ovatodiolide or Ovatodiolide related substances or an enriched plant extract containing anisomelic acid and ovatiodiolide. The pharmaceutical composition may comprise Ovatodiolide or Ovatodiolide related substances or the enriched extract in an oil-in-water emulsion, for example in an isotropic mixture of at least one oil and at least one surfactant or, alternatively, in a hydrophilic solvent and a co-solvent or surfactant or a combination thereof. A method of treating or preventing papillomavirus associated diseases in a mammal is also provided.

Abstract: A compound of Formula 1 wherein, X represents an alkyl, alkylene, alkenyl, alkenylene, alkynyl or alkynylene group, optionally having at least one substituent selected from the group of —OR1 and —NR1R2, or Y represents —OTBS, —OR1, —NR1R2; Z represents —OR3 or ?O; and R1, R2 and R3 each independently stand for H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, or heterocyclyl, optionally in the form of enantiomers racemic mixtures, or pharmaceutically acceptable salts thereof, for use as a medicament, in particular for use in anti-viral cancer treatment in mammals and for use in treatment of benign or neoplastic genital Human Papilloma Virus associated diseases and for use in treatment of non-genital warts.

Abstract: A compound of Formula 1 wherein, X represents an alkyl, alkylene, alkenyl, alkenylene, alkynyl or alkynylene group, optionally having at least one substituent selected from the group of —OR1 and —NR1R2, or Y represents —OTBS, —OR1, —NR1R2; Z represents —OR3 or ?O; and R1, R2 and R3 each independently stand for H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, or heterocyclyl, optionally in the form of enantiomers racemic mixtures, or pharmaceutically acceptable salts thereof, for use as a medicament, in particular for use in anti-viral cancer treatment in mammals and for use in treatment of benign or neoplastic genital Human Papilloma Virus associated diseases and for use in treatment of non-genital warts.