Patents by Inventor Yury V. Golstev

Yury V. Golstev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulators of the function of FAS receptors and other proteins
    Patent number: 7799901
    Abstract: The present invention provides proteins capable of modulating or mediating the FAS receptor ligand or TNF effect on cells carrying FAS receptor or p55 receptor by binding or interacting with MORT-1 protein, which in turn binds to the intracellular domain of the FAS receptor or to another protein TRADD which binds to the p55 receptor. In addition, peptide inhibitors that interfere with the proteolytic activity of MORT-1-binding proteins having proteolytic activity are provided, as well as a method of designing them.
    Type: Grant
    Filed: September 18, 2006
    Date of Patent: September 21, 2010
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: David Wallach, Mark Boldin, Tanya Goncharov, Yury V. Golstev
  • Modulators of the function of FAS receptors and other proteins
    Publication number: 20030219411
    Abstract: The present invention provides proteins capable of modulating or mediating the FAS receptor ligand or TNF effect on cells carrying FAS receptor or p55 receptor by binding or interacting with MORT-1 protein, which in turn binds to the intracellular domain of the FAS receptor or to another protein TRADD which binds to the p55 receptor. In addition, peptide inhibitors that interfere with the proteolytic activity of MORT-1-binding proteins having proteolytic activity are provided, as well as a method of designing them.
    Type: Application
    Filed: February 20, 2003
    Publication date: November 27, 2003
    Applicant: Yeda Research and Development Co., LTD
    Inventors: David Wallach, Mark Boldin, Tanya Goncharov, Yury V. Golstev
  • Modulators of the function of FAS receptors and other proteins
    Patent number: 6586571
    Abstract: The present invention provides proteins capable of modulating or mediating the FAS receptor ligand or TNF effect on cells carrying FAS receptor or p55 receptor by binding or interacting with MORT-1 protein, which in turn binds to the intracellular domain of the FAS receptor or to another protein TRADD which binds to the p55 receptor. In addition, peptide inhibitors which interfere with the proteolytic activity of MORT-1-biding proteins having proteolytic activity are provided as well as a method of designing them.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: July 1, 2003
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: David Wallach, Mark Boldin, Tanya Goncharov, Yury V. Golstev
  • Modulators of the function of FAS receptors and other proteins
    Patent number: 6399327
    Abstract: The present invention provides proteins capable of modulating or mediating the FAS receptor ligand or TNF effect on cells carrying FAS receptor or p55 receptor by binding or interacting with MORT-1 protein, which in turn binds to the intracellular domain of the FAS receptor or to another protein TRADD which binds to the p55 receptor. In addition, peptide inhibitors which interfere with the proteolytic activity of MORT-1-biding proteins having proteolytic activity are provided as well as a method of designing them.
    Type: Grant
    Filed: April 10, 1998
    Date of Patent: June 4, 2002
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: David Wallach, Mark Boldin, Tanya Goncharov, Yury V. Golstev