Abstract: Provided herein are spirolactone compounds of Formula I that are useful as inhibitors of ACC1 and/or ACC2. The spirolactone compounds described herein can be used for treating a disease or disorder associated with aberrant ACC1 and/or ACC2 activities, for example, non-alcoholic steatohepatitis (NASH), acne, obesity, diabetes, and cancer. Also provided herein are pharmaceutical compositions comprising the spirolactone compound of Formula I, or pharmaceutically acceptable salt thereof.

Abstract: A pixel matrix driving device and a display device are provided. The pixel matrix driving device includes a pixel matrix, a timing controller and a driving circuit. The pixel matrix includes a plurality of sub-pixels, an i-th column of sub-pixels in the plurality of sub-pixels and an (i+1)-th column of sub-pixels in the plurality of sub-pixels have different polarity inversion positions. The timing controller is configured for obtaining an initial pixel value, and obtaining a first grayscale value and a second grayscale value according to the initial pixel value. The driving circuit is configured for obtaining a first driving voltage according to the first grayscale value, obtaining a second driving voltage according to the second grayscale value, and applying the first driving voltage and the second driving voltage into the pixel matrix. The disclosure can improve the horizontal equidistant horizontal stripes and improve the washout phenomenon of the display panel.

Abstract: An electrostatic discharge (ESD) device applied to a liquid crystal display (LCD) panel includes: an electrostatic concentration structure, protruded on a color film substrate of the LCD panel; and an electrostatic discharge structure, being disposed on an array substrate of the LCD panel, positionally corresponding to the electrostatic concentration structure and having an interval relative to the electrostatic concentration structure satisfying a preset interval. Or, the ESD device includes an electrostatic discharge structure disposed on an array substrate of the LCD panel and having an interval relative to a color film substrate of the LCD panel satisfying a preset interval. Therefore, the ESD device can effectively reduce damage caused by static electricity to the LCD panel, and carry out electrostatic protection on the side of color film substrate as well as on the surroundings of the display panel, so that a strong anti-static protection ability is achieved.

Abstract: A method for driving a pixel matrix is provided, and the pixel matrix includes multiple sub-pixels arranged in a matrix. Voltages applied along any one of data lines change in polarity once every four sub-pixels or every two sub-pixels, any one of the data lines controls voltage inputs of sub-pixel respectively connected to two sides thereof or controls voltage inputs of two sub-pixels both connected to one side thereof. The method includes: receiving an image data and acquiring original pixel data according to the image data; generating a first driving voltage and a second driving voltage according to the original pixel data; and loading the first driving voltage or the second driving voltage to the pixel matrix along any one of the data lines. The invention also provides a display device corresponding to the method. The invention can avoid crosstalk, bright dark lines and improve display effect.

Abstract: The invention provides a driving method for a pixel matrix. The pixel matrix includes a plurality of sub-pixels arranged in a matrix, the polarity of data lines is inverted once every two columns, the polarity of the voltage loaded in the direction of the data lines is exchanged once every N sub-pixels, and each data line alternately loads the voltage to the lth column and (I+2)th column of sub-pixels every N sub-pixels. The driving method includes: acquiring original pixel data; generating a first driving voltage and a second driving voltage according to the original pixel data; and loading the first driving voltage or the second driving voltage to the pixel matrix along the data lines within one frame, where I?1, N?2. In addition, the invention further provides a display device.

Abstract: A method for driving a pixel matrix is provided, and the pixel matrix includes multiple sub-pixels arranged in a matrix. Voltages applied along any one of data lines change in polarity once every four sub-pixels or every two sub-pixels, any one of the data lines controls voltage inputs of sub-pixel respectively connected to two sides thereof or controls voltage inputs of two sub-pixels both connected to one side thereof. The method includes: receiving an image data and acquiring original pixel data according to the image data; generating a first driving voltage and a second driving voltage according to the original pixel data; and loading the first driving voltage or the second driving voltage to the pixel matrix along any one of the data lines. The invention also provides a display device corresponding to the method. The invention can avoid crosstalk, bright dark lines and improve display effect.

Abstract: An electrostatic discharge (ESD) device applied to a liquid crystal display (LCD) panel includes: an electrostatic concentration structure, protruded on a color film substrate of the LCD panel; and an electrostatic discharge structure, being disposed on an array substrate of the LCD panel, positionally corresponding to the electrostatic concentration structure and having an interval relative to the electrostatic concentration structure satisfying a preset interval. Or, the ESD device includes an electrostatic discharge structure disposed on an array substrate of the LCD panel and having an interval relative to a color film substrate of the LCD panel satisfying a preset interval. Therefore, the ESD device can effectively reduce damage caused by static electricity to the LCD panel, and carry out electrostatic protection on the side of color film substrate as well as on the surroundings of the display panel, so that a strong anti-static protection ability is achieved.

Abstract: The invention provides a display panel, including a color filter substrate and a thin film transistor array substrate disposed oppositely, and a liquid crystal layer filled between the color filter substrate and the thin film transistor array substrate, wherein the thin film transistor array substrate includes a display area, a non-display area, and a plurality of photo sensors are disposed in the display area; the color filter substrate is formed with a plurality of light transmissive passages; the thin film transistor array substrate is disposed with a plurality of sub-pixels; and the photo sensor is configured for detecting position information corresponding to an external photoelectric signal when receiving the external photoelectric signal. The display panel is provided with a plurality of photo sensors, when the incident laser light is irradiated onto the photo sensor, the photo sensor can be triggered to work, and the laser projection position is determined.

Abstract: A method for driving a pixel matrix is provided, and the pixel matrix includes multiple sub-pixels arranged in a matrix. Voltages applied along any one of data lines change in polarity once every four sub-pixels or every two sub-pixels, any one of the data lines controls voltage inputs of sub-pixel respectively connected to two sides thereof or controls voltage inputs of two sub-pixels both connected to one side thereof. The method includes: receiving an image data and acquiring original pixel data according to the image data; generating a first driving voltage and a second driving voltage according to the original pixel data; and loading the first driving voltage or the second driving voltage to the pixel matrix along any one of the data lines. The invention also provides a display device corresponding to the method. The invention can avoid crosstalk, bright dark lines and improve display effect.

Abstract: The present invention discloses a liquid crystal display panel and a liquid crystal display device, the liquid crystal display panel includes: a plurality of data lines and a plurality of scan lines, wherein the plurality of data lines intersect with the plurality of scan lines to define X rows and Y columns of pixel units arranged in a matrix, S types of different polarity inversion positions are existed from an i-th column of pixel unit to an [i+(U?1)]-th column of pixel unit, where 0<i<Y, U?4, S?2, and U is a polarity inversion repetition period in a scan line direction. The liquid crystal display panel and the liquid crystal display device provided by the present invention can alleviate the phenomenon of horizontal equidistant horizontal stripes, and can reduce the problem of excessive power consumption and temperature increase caused by driving.

Abstract: The invention provides a pixel matrix display device, which includes a timing controller, a data driving unit, a scan driving unit and a pixel matrix; the pixel matrix includes a plurality of sub-pixels arranged in a matrix; the timing controller is configured to acquire an original signal input data, and convert the original signal input data into a first grayscale data and a second grayscale data; the scan driving unit is configured to load a scan signal to the pixel matrix; and within a frame, the data driving unit is configured to load a first grayscale driving voltage corresponding to the first grayscale data or a second grayscale driving voltage corresponding to the second grayscale data to the pixel matrix along a direction of each data line; wherein, an aspect ratio a/b of the sub-pixel satisfies the relationship: 0.675?a/b?1.48.

Abstract: A pixel matrix driving device and a display device are provided. The pixel matrix driving device includes a pixel matrix, a timing controller and a driving circuit. The pixel matrix includes a plurality of sub-pixels, an i-th column of sub-pixels in the plurality of sub-pixels and an (i+1)-th column of sub-pixels in the plurality of sub-pixels have different polarity inversion positions. The timing controller is configured for obtaining an initial pixel value, and obtaining a first grayscale value and a second grayscale value according to the initial pixel value. The driving circuit is configured for obtaining a first driving voltage according to the first grayscale value, obtaining a second driving voltage according to the second grayscale value, and applying the first driving voltage and the second driving voltage into the pixel matrix. The disclosure can improve the horizontal equidistant horizontal stripes and improve the washout phenomenon of the display panel.

Abstract: The invention provides a display panel, including a color filter substrate and a thin film transistor array substrate disposed oppositely, and a liquid crystal layer filled between the color filter substrate and the thin film transistor array substrate, wherein the thin film transistor array substrate includes a display area, a non-display area, and a plurality of photo sensors are disposed in the display area; the color filter substrate is formed with a plurality of light transmissive passages; the thin film transistor array substrate is disposed with a plurality of sub-pixels; and the photo sensor is configured for detecting position information corresponding to an external photoelectric signal when receiving the external photoelectric signal. The display panel is provided with a plurality of photo sensors, when the incident laser light is irradiated onto the photo sensor, the photo sensor can be triggered to work, and the laser projection position is determined.

Abstract: The present invention discloses a liquid crystal display panel and a liquid crystal display device, the liquid crystal display panel includes: a plurality of data lines and a plurality of scan lines, wherein the plurality of data lines intersect with the plurality of scan lines to define X rows and Y columns of pixel units arranged in a matrix, S types of different polarity inversion positions are existed from an i-th column of pixel unit to an [i+(U?1)]-th column of pixel unit, where 0<i<Y, U?4, S?2, and U is a polarity inversion repetition period in a scan line direction. The liquid crystal display panel and the liquid crystal display device provided by the present invention can alleviate the phenomenon of horizontal equidistant horizontal stripes, and can reduce the problem of excessive power consumption and temperature increase caused by driving.

Abstract: The invention provides a driving method for a pixel matrix. The pixel matrix includes a plurality of sub-pixels arranged in a matrix, the polarity of data lines is inverted once every two columns, the polarity of the voltage loaded in the direction of the data lines is exchanged once every N sub-pixels, and each data line alternately loads the voltage to the lth column and (l+2)th column of sub-pixels every N sub-pixels. The driving method includes: acquiring original pixel data; generating a first driving voltage and a second driving voltage according to the original pixel data; and loading the first driving voltage or the second driving voltage to the pixel matrix along the data lines within one frame, where l?, N?2. In addition, the invention further provides a display device.

Abstract: The invention provides a pixel matrix display device, which includes a timing controller, a data driving unit, a scan driving unit and a pixel matrix; the pixel matrix includes a plurality of sub-pixels arranged in a matrix; the timing controller is configured to acquire an original signal input data, and convert the original signal input data into a first grayscale data and a second grayscale data; the scan driving unit is configured to load a scan signal to the pixel matrix; and within a frame, the data driving unit is configured to load a first grayscale driving voltage corresponding to the first grayscale data or a second grayscale driving voltage corresponding to the second grayscale data to the pixel matrix along a direction of each data line; wherein, an aspect ratio a/b of the sub-pixel satisfies the relationship: 0.675?a/b?1.48.

Abstract: A peering relationship among two or more network appliances is established through an exchange of control messages among the network appliances. The peering relationship defines a cluster of peered network appliances, and at each network appliance of the cluster traffic flow state information for all the network appliances of the cluster is maintained. Network traffic associated with traffic flows of the network appliances of the cluster is managed according to the state information for the traffic flows. This managing of the network traffic may include forwarding among the network appliances of the cluster (i.e., to those of the appliances handling the respective flows) at least some of the network traffic associated with one or more of the traffic flows according to the state information for the one or more traffic flows. The traffic flows may be TCP connections or UDP flows.

Abstract: A peering relationship among two or more network appliances is established through an exchange of control messages among the network appliances. The peering relationship defines a cluster of peered network appliances, and at each network appliance of the cluster traffic flow state information for all the network appliances of the cluster is maintained. Network traffic associated with traffic flows of the network appliances of the cluster is managed according to the state information for the traffic flows. This managing of the network traffic may include forwarding among the network appliances of the cluster (i.e., to those of the appliances handling the respective flows) at least some of the network traffic associated with one or more of the traffic flows according to the state information for the one or more traffic flows. The traffic flows may be TCP connections or UDP flows.

Abstract: A peering relationship among two or more network appliances is established through an exchange of control messages among the network appliances. The peering relationship defines a cluster of peered network appliances, and at each network appliance of the cluster traffic flow state information for all the network appliances of the cluster is maintained. Network traffic associated with traffic flows of the network appliances of the cluster is managed according to the state information for the traffic flows. This managing of the network traffic may include forwarding among the network appliances of the cluster (i.e., to those of the appliances handling the respective flows) at least some of the network traffic associated with one or more of the traffic flows according to the state information for the one or more traffic flows. The traffic flows may be TCP connections or UDP flows.

Abstract: In one embodiment, an intermediary device situated along a communication path between two endpoint devices may receive communication packets sent along the communication path. If the intermediary device receives a connection-initiating packet having a customization indicator and a connection-acknowledgement packet having a customization indicator, then the intermediary device may install a bypass rule.