Abstract: One of pairs of an exciter and a sensor is selected in accordance with the detection signal which is derived from an exciter waveform induced in an artery transmitted therethrough. The pairs of exciters and sensors are arranged on a substrate in various formations. A/D converters are provided to respective detection signals. A frequency of the oscillation signal supplied to the exciter is controlled by various oscillation signal generation circuits. Bandpass filtering for extracting the exciter waveform, low-pass-filtering for extracting a natural blood pressure waveform, phase difference detection processes are provided by a microprocessor, wherein the bandpass filtering and low-pass-filtering processes may be replaced with a bandpass filter and a low pass filter, and their outputs are selected by a switching circuit and supplied to the microprocessor through one a/d converter.

Abstract: A physical parameter measuring system is provided which measures a physical parameter such as a blood pressure of a person using oscillation transmission. The system includes a phase detector, an A/D converter, an arc center determining circuit, and a phase angle determining circuit. The phase detector detects a phase of a sensor signal produced, in sequence, by monitoring oscillations which are applied by an exciter and transmitted through a living body to map the signal on a two-dimensional plane as a sample point. The A/D converter converts the sample point signal into a digital sample point signal in sequence. The arc center determining circuit determines a center of an arc defined by a distribution of the sample points mapped for a given period of time.

Abstract: One of pairs of an exciter and a sensor is selected in accordance with the detection signal which is derived from an exciter waveform induced in an artery transmitted therethrough. The pairs of exciters and sensors are arranged on a substrate in various formations. A/D converters are provided to respective detection signals. A frequency of the oscillation signal supplied to the exciter is controlled by various oscillation signal generation circuits. Bandpass filtering for extracting the exciter waveform, low-pass-filtering for extracting a natural blood pressure waveform, phase difference detection processes are provided by a microprocessor, wherein the bandpass filtering and low-pass-filtering processes may be replaced with a bandpass filter and a low pass filter, and their outputs are selected by a switching circuit and supplied to the microprocessor through one a/d converter.

Abstract: A blood pressure determining apparatus is provided which applies oscillations to the blood vessel of a subject through an exciter to determine the blood pressure based on the frequency of the oscillations propagated through the blood vessel measured by an oscillation sensor. The apparatus monitors an output of the oscillation sensor when the exciter applies no oscillation to the subject to determine the power spectrum of noise signals contained in the output and sets the frequency of oscillations to be applied to the blood vessel to any value within a band of the power spectrum in which the power of noise is small. This enables the blood pressure to be determined without influence of any electric disturbances from peripheral devices.

Abstract: A mouse-human chimaeric immunoglobulin heavy chain comprising (a) the amino acid sequence of a mouse immunoglobulin heavy chain variable region and (b) the amino acid sequence of a human immunoglobulin heavy chain constant region and reacting specifically with human common acute lympohocytic leukemia antigen and a chimaeric DNA fragment which encodes the amino acid sequence of the above mouse-human chimaeric immunoglobulin heavy chain.

Abstract: A DNA sequence comprising a polynucleotide segment consisting of a DNA sequence (A) shown below and a DNA sequence complementary thereto: ##STR1## wherein A represents deoxyadenosine-5'-phosphate, C represents deoxycytidine-5'-phosphate, G represents deoxyguanosine-5'-phosphate, and T represents deoxythymidine-5'-phosphate.The DNA sequence provided by this invention is derived from a rearranged immunoglobulin heavy chain variable (V.sub.H) region gene taken from the mouse hybridoma NL-1 cells which produce an antibody capable of commonly recognizing surface antigens of various human acute lyphocytic leukemia cells. Accordingly, if, for example, it is combined with a heavy chain constant (C.sub.H) region gene, a heavy chain can be produced which can recognize commonly various human acute lymphocytic leukemia cells in combination with a proper light chain. This would serve for the diagnosis and treatment of human acute lymphocytic leukemia.