Patents by Inventor Yushi Xiao

Yushi Xiao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminoquinazoline compounds as Aantagonist
    Patent number: 10138212
    Abstract: The present invention is directed to compounds of generic formula I: or pharmaceutically acceptable salts thereof that are believed to be useful as an A2A-receptor antagonist.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: November 27, 2018
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Amjad Ali, Rongze Kuang, Yeon-Hee Lim, Michael Man-Chu Lo, Pauline C. Ting, Purakkattle Biju, Manuel de Lera Ruiz, Sylvia J. Degrado, Alexander L. Tung, Timothy J. Henderson, Liwu Hong, Jae-Hun Kim, Dong Won-Shik Kim, Joe Lee, Jie Wu, Heping Wu, Yushi Xiao, Tao Yu, Gang Zhou, Xiaohong Zhu, Kevin D. McCormick, Jayaram R. Tagat, Dong Xiao, Tanweer Khan, Jianhua Cao, Michael Berlin, Yonglian Zhang
  • AMINOQUINAZOLINE COMPOUNDS AS A2A ANTAGONIST
    Publication number: 20180037554
    Abstract: The present invention is directed to compounds of generic formula I: or pharmaceutically acceptable salts thereof that are believed to be useful as an A2A-receptor antagonist.
    Type: Application
    Filed: February 1, 2016
    Publication date: February 8, 2018
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Amjad Ali, Rongze Kuang, Yeon-Hee Lim, Michael Man-Chu Lo, Pauline C. Ting, Purakkattle Biju, Manuel de Lera Ruiz, Sylvia J. Degrado, Alexander L. Tung, Timothy J. Henderson, Liwu Hong, Jae-Hun Kim, Dong Won-Shik Kim, Joe Lee, Jie Wu, Heping Wu, Yushi Xiao, Tao Yu, Gang Zhou, Xiaohong Zhu, Kevin D. McCormick, Jayaram R. Tagat, Dong Xiao, Tanweer Khan, Jianhua Cao, Michael Berlin, Yonglian Zhang
  • Compounds for inhibiting KSP Kinesin activity
    Publication number: 20060281778
    Abstract: The present invention provides compounds of Formula I (wherein R1, R3, X, W, Z and ring Y are as defined herein). The present invention also provides compositions comprising these compounds that are useful for treating cellular proliferative diseases or disorders associated with KSP kinesin activity and for inhibiting KSP kinesin activity.
    Type: Application
    Filed: March 7, 2006
    Publication date: December 14, 2006
    Inventors: Jayaram Tagat, Timothy Guzi, Marc Labroli, Cory Poker, Angela Kerekes, Tao Yu, Hon-Chung Tsui, Neng-Yang Shih, Yushi Xiao, Sunil Paliwal
  • Compounds for inhibiting KSP kinesin activity
    Publication number: 20060247320
    Abstract: The present invention provides compounds of Formula I (wherein R1, R3, X, W, Z and ring Y are as defined herein). The present invention also provides compositions comprising these compounds that are useful for treating cellular proliferative diseases or disorders associated with KSP kinesin activity and for inhibiting KSP kinesin activity.
    Type: Application
    Filed: March 7, 2006
    Publication date: November 2, 2006
    Inventors: Jayaram Tagat, Timothy Guzi, Marc Labroli, Cory Poker, Yushi Xiao, Angela Kerekes, Tao Yu, Sunil Paliwal, Hon-Chung Tsui, Neng-Yang Shih, Stuart McCombie, Vincent Madison, Charles Lesburg, Jose Duca