Patents by Inventor Yusong GUO

Yusong GUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Disruption of EGFR-SAR1 interaction for cancer treatment
    Patent number: 10663465
    Abstract: The present invention relates to the discovery that delivery of EGFR to cell surface requires EGFR-SAR1A binding. Thus, the invention provides a method for identifying inhibitors of EGFR-SAR1A binding, which can serve as therapeutic agents for treating conditions involving undesirable EGFR signaling. The invention also provides novel composition and its use that suppresses the specific binding between EGFR and SAR1A for the purpose of treating or preventing a condition involving undesired EGFR signaling.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: May 26, 2020
    Assignee: The Hong Kong University of Science and Technology
    Inventors: Yusong Guo, Pik Ki Lau, Yixin Lin
  • DISRUPTION OF EGFR-SAR1 INTERACTION FOR CANCER TREATMENT
    Publication number: 20190277844
    Abstract: The present invention relates to the discovery that delivery of EGFR to cell surface requires EGFR-SAR1A binding. Thus, the invention provides a method for identifying inhibitors of EGFR-SAR1A binding, which can serve as therapeutic agents for treating conditions involving undesirable EGFR signaling. The invention also provides novel composition and its use that suppresses the specific binding between EGFR and SAR1A for the purpose of treating or preventing a condition involving undesired EGFR signaling.
    Type: Application
    Filed: January 22, 2019
    Publication date: September 12, 2019
    Inventors: Yusong GUO, Pki Ki LAU, Yixin LIN