Patents by Inventor Yusuke Ayata

Yusuke Ayata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DRUG SUBSTANCE OF LEMBOREXANT AND MEDICINAL COMPOSITION COMPRISING SAME
    Publication number: 20230103250
    Abstract: There is provided a pharmaceutical composition comprising lemborexant exhibiting a favorable dissolution profile by using a granular material having a 90% cumulative diameter (D90) of 64 ?m or less as a lemborexant active pharmaceutical ingredient.
    Type: Application
    Filed: January 14, 2021
    Publication date: March 30, 2023
    Inventors: Taichi ABE, Yusuke AYATA, Nobuya SUZUKI, Yurie AKIMOTO, Futoshi SHIKATA, Yasuhiro Zaima, Nobuo YOSHIDA
  • METHOD AND COMPOUND USEFUL IN PREPARATION OF OREXIN-2 RECEPTOR ANTAGONIST, AND LEMBOREXANT HAVING FEW IMPURITIES
    Publication number: 20220194925
    Abstract: The present application discloses a method and a compound that are useful for preparation of a compound of Formula (XI). Furthermore, the present application discloses the compound of Formula (XI) comprising a small amount of impurities.
    Type: Application
    Filed: May 13, 2020
    Publication date: June 23, 2022
    Inventors: Taichi Abe, Kazuhiro Yoshizawa, Yuzo Watanabe, Takeshi Miura, Yusuke Ayata, Yoshinori Yasuda
  • High-Purity Quinoline Derivative and Method for Manufacturing Same
    Publication number: 20220048862
    Abstract: Provided is a compound represented by formula (IV) or a salt thereof, wherein the content of the compound represented by formula (I) is 350 ppm by mass or less.
    Type: Application
    Filed: October 27, 2021
    Publication date: February 17, 2022
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Taiju Nakamura, Taichi Abe, Yusuke Miyashita, Hirofumi Kuroda, Yusuke Ayata, Atsushi Akao
  • High-purity quinoline derivative and method for manufacturing same
    Patent number: 11186547
    Abstract: Provided is a compound represented by formula (IV) or a salt thereof, wherein the content of the compound represented by formula (I) is 350 ppm by mass or less.
    Type: Grant
    Filed: September 16, 2020
    Date of Patent: November 30, 2021
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Taiju Nakamura, Taichi Abe, Yusuke Miyashita, Hirofumi Kuroda, Yusuke Ayata, Atsushi Akao
  • High-Purity Quinoline Derivative and Method for Manufacturing Same
    Publication number: 20200407322
    Abstract: Provided is a compound represented by formula (IV) or a salt thereof, wherein the content of the compound represented by formula (I) is 350 ppm by mass or less.
    Type: Application
    Filed: September 16, 2020
    Publication date: December 31, 2020
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Taiju Nakamura, Taichi Abe, Yusuke Miyashita, Hirofumi Kuroda, Yusuke Ayata, Atsushi Akao
  • High-purity quinoline derivative and method for manufacturing same
    Patent number: 10822307
    Abstract: Provided is a compound represented by formula (IV) or a salt thereof, wherein the content of the compound represented by formula (I) is 350 ppm by mass or less.
    Type: Grant
    Filed: September 3, 2019
    Date of Patent: November 3, 2020
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Taiju Nakamura, Taichi Abe, Yusuke Miyashita, Hirofumi Kuroda, Yusuke Ayata, Atsushi Akao
  • High-Purity Quinoline Derivative and Method for Manufacturing Same
    Publication number: 20190389804
    Abstract: Provided is a compound represented by formula (IV) or a salt thereof, wherein the content of the compound represented by formula (I) is 350 ppm by mass or less.
    Type: Application
    Filed: September 3, 2019
    Publication date: December 26, 2019
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Taiju Nakamura, Taichi Abe, Yusuke Miyashita, Hirofumi Kuroda, Yusuke Ayata, Atsushi Akao
  • High-purity quinoline derivative and method for manufacturing same
    Patent number: 10407393
    Abstract: Provided is a compound represented by formula (IV) or a salt thereof, wherein the content of the compound represented by formula (I) is 350 ppm by mass or less.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: September 10, 2019
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Taiju Nakamura, Taichi Abe, Yusuke Miyashita, Hirofumi Kuroda, Yusuke Ayata, Atsushi Akao
  • HIGH-PURITY QUINOLINE DERIVATIVE AND METHOD FOR MANUFACTURING SAME
    Publication number: 20190185432
    Abstract: Provided is a compound represented by formula (IV) or a salt thereof, wherein the content of the compound represented by formula (I) is 350 ppm by mass or less.
    Type: Application
    Filed: December 21, 2018
    Publication date: June 20, 2019
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Taiju Nakamura, Taichi Abe, Yusuke Miyashita, Hirofumi Kuroda, Yusuke Ayata, Atsushi Akao
  • High-purity quinoline derivative and method for manufacturing same
    Patent number: 10259791
    Abstract: Provided is a compound represented by formula (IV) or a salt thereof, wherein the content of the compound represented by formula (I) is 350 ppm by mass or less.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: April 16, 2019
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Taiju Nakamura, Taichi Abe, Yusuke Miyashita, Hirofumi Kuroda, Yusuke Ayata, Atsushi Akao
  • HIGH-PURITY QUINOLINE DERIVATIVE AND METHOD FOR MANUFACTURING SAME
    Publication number: 20170233344
    Abstract: Provided is a compound represented by formula (IV) or a salt thereof, wherein the content of the compound represented by formula (I) is 350 ppm by mass or less.
    Type: Application
    Filed: August 26, 2015
    Publication date: August 17, 2017
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Taiju Nakamura, Taichi Abe, Yusuke Miyashita, Hirofumi Kuroda, Yusuke Ayata, Atsushi Akao
  • Crystalline form of the salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide or the solvate of the salt and a process for preparing the same
    Patent number: 7612208
    Abstract: A crystal of a 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide hydrochloride, hydrobromide, p-toluenesulfonate, sulfate, methanesulfonate or ethanesulfonate, or a solvate thereof.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: November 3, 2009
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Tomohiro Matsushima, Taiju Nakamura, Kazuhiro Yoshizawa, Atsushi Kamada, Yusuke Ayata, Naoko Suzuki, Itaru Arimoto, Takahisa Sakaguchi, Masaharu Gotoda