Abstract: The present invention aims to provide an electrophoresis apparatus which makes it possible to execute protein analysis with a high throughput. The electrophoresis apparatus according to the present invention is equipped with a capillary array which is configured by arraying a plurality of capillaries, a measurement light irradiation unit which irradiates with measurement light, a first lens array which includes a plurality of first lenses which are arrayed in correspondence with the plurality of capillaries, a second lens array which includes a plurality of second lenses which are arrayed in correspondence with the plurality of capillaries, and a light receiving unit which receives light which is incident upon the capillaries via the first lens array from the measurement light irradiation unit via the second lens array.

Abstract: An imaging processing apparatus according to one embodiment of the disclosure includes an extractor that extracts a feature quantity included in a captured image, and an object identifier that identifies an object on the basis of the feature quantity. The extractor extracts the feature quantity by executing, on the basis of the captured image, a convolution calculation using a filter including multiple filter values that are arranged two-dimensionally. The multiple filter values in the filter are set at respective values that are line-symmetric with respect to an axis of symmetry along a predetermined direction.

Abstract: The present invention aims to provide an electrophoresis apparatus which makes it possible to execute protein analysis with a high throughput. The electrophoresis apparatus according to the present invention is equipped with a capillary array which is configured by arraying a plurality of capillaries, a measurement light irradiation unit which irradiates with measurement light, a first lens array which includes a plurality of first lenses which are arrayed in correspondence with the plurality of capillaries, a second lens array which includes a plurality of second lenses which are arrayed in correspondence with the plurality of capillaries, and a light receiving unit which receives light which is incident upon the capillaries via the first lens array from the measurement light irradiation unit via the second lens array.

Abstract: A vehicle exterior environment recognition apparatus includes a stereo speed derivation unit, a monocular speed derivation unit, a predicted speed derivation unit, a mixture ratio derivation unit, and an object speed derivation unit. The stereo speed derivation unit derives a stereo speed indicating a speed of a three-dimensional object extracted from a distance image derived from luminance images of two image-capturing units. The monocular speed derivation unit derives a monocular speed indicating a speed of the three-dimensional object extracted from the luminance image of one of the image-capturing units. The predicted speed derivation unit derives a predicted speed based on a past speed of the three-dimensional object. The mixture ratio derivation unit derives a mixture ratio of the stereo, monocular, and predicted speeds. The object speed derivation unit mixes the stereo, monocular, and predicted speeds at the mixture ratio, to derive an object speed.

Abstract: Provided is a method for generating a trained model for classifying blocking event data representing nanopore blocking events in a biomolecule measurement device. The method includes generating a first trained model by executing machine learning of a training model using first teacher data, the first teacher data includes teacher blocking event data and a teacher label, the teacher label indicates whether the teacher blocking event data is classified as Good data or bad data, and the first trained model is configured to classify the blocking event data into good data or bad data. In addition, a method for determining a base sequence a biomolecule and a biomolecule measurement device are provided.

Abstract: The present invention aims to provide an electrophoresis apparatus which makes it possible to execute protein analysis with a high throughput. The electrophoresis apparatus according to the present invention is equipped with a capillary array which is configured by arraying a plurality of capillaries, a measurement light irradiation unit which irradiates with measurement light, a first lens array which includes a plurality of first lenses which are arrayed in correspondence with the plurality of capillaries, a second lens array which includes a plurality of second lenses which are arrayed in correspondence with the plurality of capillaries, and a light receiving unit which receives light which is incident upon the capillaries via the first lens array from the measurement light irradiation unit via the second lens array.

Abstract: A biomolecule is more easily and reliably reciprocated in a nanopore. An adapter molecule that directly or indirectly binds to a biomolecule to be analyzed comprises a three-dimensional structure formation domain consisting of a single-stranded nucleotide.

Abstract: An image processing apparatus includes an extractor and an object identifier. The extractor extracts a left feature quantity included in a left image of a stereo image and a right feature quantity included in a right image of the stereo image by executing a convolution calculation multiple times on the basis of the left and right images with securing horizontal symmetry between the left feature quantity and the right feature quantity, and executes, at the convolution calculation, a concatenation process of concatenating pixel values between the left feature quantity and the right feature quantity using a calculation process to secure the horizontal symmetry. The object identifier performs object identification of an object on the basis of the left feature quantity and the right feature quantity.

Abstract: In a base sequence determination system that performs a complementary strand synthesis reaction of a template DNA strand using DNA polymerase, a complementary strand synthesized by DNA polymerase is degraded by exonuclease in a solution.

Abstract: An apparatus for storing a thin film device, the apparatus including: a thin film device 3 having an insulating thin film containing Si and having a thickness of 100 nm or less; a solution in contact with the thin film; and a container having a tank that seals the solution, wherein the solution is a solution that satisfies any of the following conditions (1) to (3). (1) A solution containing water in a volume ratio of 0% or more to 30% or less (2) A solution cooled and maintained at a temperature equal to or higher than a solidification point and lower than 15° C. (3) A solution that contains a salt with a concentration of 1 mol/L or more and a saturation concentration or less and is cooled and maintained to a temperature equal to or higher than a solidification point and lower than 25° C.

Abstract: An image processing apparatus includes an extractor and an object identifier. The extractor is configured to extract a feature quantity included in a captured image. The object identifier is configured to perform identification of an object on the basis of the feature quantity. The extractor is configured to extract the feature quantity by performing, on the captured image, a convolution calculation multiple times using a filter including multiple filter values that are two-dimensionally arranged. The multiple filter values are initially set at values that are line-symmetric with respect to an axis of symmetry along a predetermined direction. Augmentation batch data of learning data to be used in an update process of the filter by machine learning is configured to include any unflipped image extracted and a flipped image as paired images, the flipped image resulting from applying image-flipping to the unflipped image with respect to the axis of symmetry.

Abstract: A double-stranded DNA to be analyzed is analyzed without subjecting it to a modification treatment. An adapter molecule to be bound to the double-stranded DNA to be analyzed has a double-stranded nucleic acid region having base sequences complementary to each other, a pair of single-stranded nucleic acid regions having base sequences non-complementary to each other, and a block molecule placed in one of the single-stranded nucleic acid regions.

Abstract: A first modulation voltage is applied to a thin film. An amount of a change in the phase of a current carried through the thin film with respect to the phase of the first modulation voltage is compared with a threshold. Upon detecting that the amount of the change in the phase exceeds the threshold is detected, the application of the first modulation voltage is stopped. Thus, a nanopore is formed on the thin film at high speed.

Abstract: An object of the present invention is to provide a biomolecule measuring device that can decrease the influence of crosstalk between chambers. A biomolecule measuring device according to the present invention supplies, to electrodes equipped on chambers, voltages modulated differently to each other.

Abstract: An electrophoresis data correction device or a post-color-call data correction device selects specific wavelength data from first data, performs filtering processing to cut some or all of components on a high frequency side, compares peak intensities of the specific wavelength data before and after the filtering processing for each cutoff frequency, calculates, as a first cutoff frequency, the minimum cutoff frequency at which a decrease in peak intensity of the specific wavelength data falls within a predetermined allowable range, and corrects the first data or post-color-call data of the first data by performing filtering processing with the first cutoff frequency.

Abstract: Provided are a first tank; a second tank; a thin film having a nanopore, which communicates the first tank to the second tank, and disposed between the first and second tanks; a first electrode provided in the first tank; and a second electrode provided in the second tank. A wall surface of the nanopore has an ion adsorption preventing structure to prevent desorption/adsorption of an ion contained in a solution filling the first tank and/or the second tank, and a voltage is applied between the first and second electrodes to measure an ion current flowing through the nanopore.

Abstract: A biopolymer analysis device includes an insulating thin film that is made of an inorganic material, a first liquid tank and a second liquid tank that are separated by the thin film, a plurality of first electrodes that is arranged in the first liquid tank, and a second electrode that is disposed in the second liquid tank. A water-repellent liquid and a plurality of liquid droplets are introduced into the first liquid tank, the plurality of first electrodes is configured to be able to convey the plurality of droplets introduced into the first liquid tank by electro wetting on dielectric by applying a certain voltage, and the plurality of droplets is conveyed to portions coming into contact with the plurality of first electrodes, and is insulated from each other by the water-repellent liquid.

Abstract: The purpose of the present invention is to provide a method for treating biomolecules and a method for analyzing biomolecules with which it is possible to effectively suppress the clog of nanopores. The present invention is a method for treating biomolecules for analysis in which nanopores are used, wherein the method includes a step for preparing a sample solution that includes ammonium cations represented by a prescribed formula and biomolecules in which at least a portion of the higher-order structure has been fused.

Abstract: To slow down the speed of a biopolymer passing through a nanopore during electrophoresis to such a speed that enables a monomer sequence analysis to be performed. A biopolymer analysis device includes two tanks 101a and 101b each capable of storing a solution containing a biopolymer and an electrolyte, a pair of electrodes 105a and 105b, a thin film 104 with a nanopore, and a three-dimensional structure 103 disposed on the thin film. The three-dimensional structure has a void that can store a solution, and the void forms a flow channel, the flow channel being adapted to allow the solution to pass therethrough from the nanopore to a portion above the three-dimensional structure, and having on its surface a functional group capable of adsorbing the biopolymer. Thus, when a voltage is applied, the three-dimensional structure is not re-dispersed in the solution at least in the range of a hemisphere having the nanopore as the center and having a biopolymer trapping length r as the radius.

Abstract: Provided is a technique for moving all of a droplet from a microchannel in which the droplet have been introduced to another layer. The droplet transport device of the present disclosure includes a substrate having a through-hole or a recess, a first electrode provided on the substrate along the surface of the substrate and arranged at a position adjacent to the through-hole or the recess, a plurality of second electrodes provided on the substrate along a surface of the substrate and to which a voltage for moving the droplet introduced on the substrate is applied, and a dielectric layer covering the surface of the substrate, the first electrode, and the second electrodes, and a water-repellent film provided on the inner wall surface of the through-hole or the recess, and on the dielectric layer.