Abstract: In an aeration method for an isolator system, an incubator is connected to an isolator through a chamber. After closing a door at each sidewall of the chamber, a decontaminating gas is supplied to the chamber through gas supply passages to decontaminate the inside thereof. Next, air is supplied into the chamber through the gas supply passages and an initial aeration is carried out by discharging the decontamination gas through a gas discharge passage. Then, after a door between the isolator and the chamber is opened, and blowers are stopped, gas at a positive pressure in the isolator is introduced into the chamber. The decontaminating gas in the chamber is rapidly discharged to an outside through the gas supply passages and the gas discharge passage, and aeration in the chamber is completed. The time required for aeration of the chamber can be drastically reduced as compared with conventional aeration processes.

Abstract: In a state where an incubator 3 is connected to an isolator 2 through a chamber 4 and opening/closing doors 11B and 12 are closed, a decontaminating gas G is supplied to the chamber 4 through gas supply passages 16 and 26, and an inside thereof is decontaminated (FIGS. 2(a), (b)). Subsequently, an air is supplied into the chamber 4 through the gas supply passages 16 and 26 and initial aeration is carried out by discharging a gas in the chamber 4 through a gas discharge passage 27 (FIG. 2(b)). Subsequently, after the opening/closing door 11B is opened, when both blowers B1 and B4 are stopped, the gas at a positive pressure in the isolator 2 is introduced into the chamber 4 (FIG. 2(c)). Thus, the gas containing the decontaminating gas G in the chamber 4 is rapidly discharged to an outside through the gas supply passages 26 and 16 and the gas discharge passage 27, and aeration in the chamber 4 is completed. Time required for the aeration of the chamber 4 can be drastically reduced as compared with before.

Abstract: An electron beam cap-sterilizer radiates an electron beam onto caps while the caps are continuously conveyed. The caps are conveyed in the restricting conveying section while the movements of the caps are restricted, so that the caps roll down freely and separately from each other in the free conveying section. The electron beam radiating device emits electron beams onto the inside of the caps in the lateral direction while the caps are conveyed in the free conveying section. A deflecting device is provided in the free conveying section. The deflecting device is located at the opposite side of the electron beam radiating device to deflect the electron beams emitted by the electron beam radiating device onto the outside of the caps.

Abstract: A sterilized connection apparatus 4 includes a sealing unit 9 which forms a decontamination space S1 between an isolator 2 provided with a first cover body 11 and an incubator 3 provided with a second cover body 21, a decontamination medium supplying unit 10 which supplies a decontamination medium to the decontamination space S1 via a supply pipe line 41, and a discharge pipe line 43 which discharges the decontamination medium of the decontamination space S1. Since the decontamination space is formed as a circular decontamination space of a small capacity surrounding the cover bodies, decontamination can be efficiently performed.

Abstract: A sterilized connection apparatus 4 includes a sealing unit 9 which forms a decontamination space S1 between an isolator 2 provided with a first cover body 11 and an incubator 3 provided with a second cover body 21, a decontamination medium supplying unit 10 which supplies a decontamination medium to the decontamination space S1 via a supply pipe line 41, and a discharge pipe line 43 which discharges the decontamination medium of the decontamination space S1. Since the decontamination space is formed as a circular decontamination space of a small capacity surrounding the cover bodies, decontamination can be efficiently performed.