Abstract: Provided is a substance capable of effectively suppressing cancer metastasis or a pharmaceutical composition that effectively acts on an inflammatory disease. The pharmaceutical composition is a pharmaceutical composition containing, as an active ingredient, an antibody or an antibody fragment thereof having antigen-binding activity for an S100A8/A9 heterodimer, and blocks interaction between S100A8/A9 and a group of receptors therefor, to thereby strongly suppress cancer metastasis both in vitro and in vivo, or alleviate inflammation. That is, the anti-S100A8/A9 antibody or the antibody fragment thereof can strongly suppress cancer metastasis or alleviate inflammation, by virtue of its blocking action on the interaction between S100A8/A9 and the group of receptors therefor.

Abstract: When a controller performs a defrosting operation in which frost on an outdoor heat exchanger is caused to be melted, the controller is configured to perform a first defrosting control in which a switching state of a switching device is set to a first state, after the controller performs the first defrosting control, perform a second defrosting control in which the switching state of the switching device is set to a second state, and after the controller performs the second defrosting control, perform a third defrosting control in which the switching state of the switching device is set to the first state.

Abstract: A refrigeration cycle apparatus includes: a compressor; an indoor heat exchanger; an outdoor heat exchanger including first and second outdoor heat exchangers; a bypass flow passage causing a discharge side of the compressor to communicate with the first or second outdoor heat exchanger; a flow control valve at the bypass flow passage; and a controller performing a heating operation in which the first and second outdoor heat exchangers operate as an evaporator and the indoor heat exchanger operates as a condenser and a simultaneous heating and defrosting operation in which part of refrigerant the compressor discharges is supplied to one of the first and second outdoor heat exchangers through the bypass flow passage, the other of the outdoor heat exchangers operates as an evaporator, the indoor heat exchanger operates as a condenser, and an upper limit frequency of the compressor changes to a value higher than in the heating operation.

Abstract: A vibration damping device including a vibration-damping device main unit inserted into a mounting space of a bracket from a lateral side and securely supported by the bracket. The bracket includes engaging pieces on respective opposed inside faces of the mounting space, and engaging action of the engaging pieces with respect to respective detent engaging faces formed on a fixture member of the vibration-damping device main unit prevents the vibration-damping device main unit from becoming dislodged from the mounting space of the bracket. Opposed walls of the mounting space are each penetrated by an aperture window, and inspection flat surfaces are separately provided to an outside surface of each engaging piece visible from an outside through the aperture window and a corresponding external side surface of the bracket that is off the aperture window. The inspection flat surfaces are parallel to each other.

Abstract: A management device for managing an operation of a cargo transportation vehicle that autonomously travels on a road with no driver and that is able to store cargo in each of a plurality of storages shielded by doors that are opened and closed includes a receiver configured to receive request information about transportation of the cargo from a user, an operation determiner configured to determine the operation of the cargo transportation vehicle so that the cargo transportation vehicle arrives at a delivery destination of the cargo, a registrant configured to register a plurality of users pre-designated as recipients of the cargo, and a processor configured to perform a process of controlling a control mechanism of the storage so that the recipient is able to unload the cargo from the storage when an authentication process on the recipient registered by the registrant has succeeded.

Abstract: A sensor element includes an element body and a porous protective layer arranged to cover a part of a surface of the element body. The protective layer includes an inlet protective layer arranged to cover a gas inlet formed in the surface of the element body, and at least a part of a face included in the surface of the element body, the face on which the gas inlet is opens, and an arithmetic average roughness Rap of an inner peripheral surface of an internal space of the inlet protective layer satisfies at least one of conditions below: the arithmetic average roughness Rap is 8 ?m or more, and the arithmetic average roughness Rap is higher than an arithmetic average roughness Rac of a bonding surface of the protective layer, the bonding surface at which the protective layer is bonded to the element body.

Abstract: An air-conditioning apparatus includes a main circuit in which a compressor, a flow switching device, an indoor heat exchanger, a pressure reducing device, and a plurality of parallel heat exchangers connected in parallel with each other are connected by pipes, a bypass pipe, a flow control device provided to the bypass pipe and configured to adjust a flow rate of refrigerant flowing through the bypass pipe, an evaporating pressure sensor configured to measure an evaporating pressure of the refrigerant, and a controller. The air-conditioning apparatus is configured to operate in a normal heating operation mode and a heating-defrosting operation mode. When an operation associated with the normal heating operation mode is switched to an operation associated with the heating-defrosting operation mode, the controller adjusts an opening degree of the flow control device using the evaporating pressure in the parallel heat exchanger and a driving frequency of the compressor.

Abstract: Motor controller device comprising a position control system that controls the position of a machine end connected to a motor, wherein the motor controller device receiving the first speed directive from the high-level controller, stored in the position control system to output a motor axis position response to the high-level controller, comprising speed controller and vibration controller in speed control system, wherein the vibration controller in speed control system comprising: a position command estimator that calculates an estimate of the location directive based on the first speed directive and the motor axis position response, a parallel vibration damping controller that extracts the frequency components that excite vibration of the machine end included in the first speed directive based on the estimated value of the location directive, and outputs the extracted frequency components.

Abstract: A resin composition for molding and an electronic component device are provided. The resin composition for molding includes: a curable resin; and an inorganic filler including a calcium titanate particle.

Abstract: An electric circuit cut-off device including a housing, a to-be-cut part, a power source, and a moving body that moves between first and second end portions on opposite sides, a fuse including a fusing portion and an arc-extinguishing material, and a pair of electrode parts connected to terminals on both sides of the fuse. The moving body is configured to cut a piece located between base pieces on both sides of the to-be-cut part and a part of the to-be-cut part and the electrode part come into contact with each other in a state where base pieces on both sides of the to-be-cut part are energized via the cut piece, and the to-be-cut part and the fuse are connected to each other; and thereafter a state in which the base pieces on both sides of the to-be-cut part are energized via the cut piece is cut off.

Abstract: According to one embodiment, a plasma treatment apparatus includes a substrate holder that holds a semiconductor substrate, a gas supply unit that supplies a mixed gas to a gas supply space formed between the semiconductor substrate and the substrate holder, a flow rate adjustment unit that adjusts a flow rate of different gases in the mixed gas, and a flow rate control unit. The mixed gas contains, for example, helium and argon, and the flow rate control that controls the flow rate adjustment unit to change the relative flow rates of helium and argon, or the like, to control a temperature of the substrate.

Abstract: A surface treatment method for preventing adhesion of powder to a powder-contacting member having a surface on which contacted powder flows in the form of a particle layer. The method includes performing surface treatment on the surface such that an arithmetic average peak curvature Spc (1/mm) of the surface is 150 to 400, a peak density Spd (piece/mm2) of the surface is 10000 to 180000, a root mean square gradient Sdq of the surface is 0.05 to 0.30, and an arithmetic average height Sa (?m) of the surface is 0.02 to 3.00, and providing a space where an air layer can exist between the particle layer and the surface.

Abstract: A method for surface treatment of a DLC coated member that includes: taking as a treatment subject a DLC coated member having a DLC film coated on a base material surface; ejecting substantially spherical ejection particles having a median diameter of from 1 ?m to 20 ?m and a falling time through air of not less than 10 s/m against a surface of the film of the member at an ejection pressure of from 0.01 MPa to 0.7 MPa; and forming dimples on the surface of the film without exposing the base material so that a total projected area of the dimples is 50% or more of a treated region and so that the surface of the DLC film is processed to an arithmetic mean height (Sa) of from 0.01 ?m to 0.1 ?m and a texture aspect ratio (Str) of 0.4 or more.

Abstract: A resin composition for molding includes an epoxy resin, a curing agent, and an inorganic filler containing at least one selected from the group consisting of calcium titanate particles and strontium titanate particles, in which a total content of the calcium titanate particles and the strontium titanate particles is 30% by volume or more and less than 60% by volume with respect to the entire inorganic filler.

Abstract: The present invention provides an electric circuit breaker device that can be downsized by reducing the distance the moving body moves.

Abstract: A film forming apparatus includes an electrode, a target holder configured to hold a film forming target so as to face the electrode, and a masking shield holder configured to hold a masking shield between the electrode and the target holder. The masking shield includes a lattice portion having a plurality of openings therein and a frame portion supporting the lattice portion.

Abstract: An electric circuit breaker, including a housing, a cut portion that is arranged in the housing and forms a part of an electric circuit, a cutting member that cuts the cut portion, and a power source arranged on a first end portion side of the housing, the electric circuit breaker including a moving body that allows the cut portion to be inserted and accommodated therein and includes the cutting member and a first arc extinguishing space adjacent to the cutting member, in which the housing includes a cylindrical portion capable of moving the moving body between the first end portion and a second end portion on a side opposite to the first end portion. The moving body is further configured such that the cutting member provided in the moving body cuts the cut portion while the moving body moves from the first end portion toward the second end portion by the power source.

Abstract: According to one embodiment, a method of manufacturing a semiconductor device includes forming a first film on a substrate. The method further includes forming a second film on the first film. The method further includes forming a recess in the first film using the second film as a mask. The second film includes a first layer having carbon and a second layer having carbon formed on the first layer. The second layer has a second carbon density lower than a first carbon density of the first layer.

Abstract: An electric circuit breaker that prevents damage due to increased internal pressure after an electric circuit is cut off and prevents an arc from leaking to the outside. Such a circuit breaker includes a housing, a cut portion that is arranged in the housing and forms a part of an electric circuit, a cutting member that cuts the cut portion, and a power source arranged on a first end portion side of the housing, the electric circuit breaker including a moving body including the cutting member, in which the housing includes a cylindrical portion capable of moving the moving body between the first end portion and a second end portion on a side opposite to the first end portion, in which the moving body is configured such that the cutting member provided in the moving body cuts a separation piece of the cut portion.