Patents by Inventor Yusuke Kono

Yusuke Kono has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10472376
    Abstract: The present invention relates to compound (I) or a salt thereof which has a ROR?t inhibitory action. In the formula (I), each symbol is as defined in the specification.
    Type: Grant
    Filed: July 2, 2014
    Date of Patent: November 12, 2019
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Satoshi Yamamoto, Junya Shirai, Mitsunori Kono, Yoshihide Tomata, Ayumu Sato, Atsuko Ochida, Yoshiyuki Fukase, Shoji Fukumoto, Tsuneo Oda, Hidekazu Tokuhara, Naoki Ishii, Yusuke Sasaki
  • Publication number: 20190283288
    Abstract: Provided is a foamed heat-insulating material which encapsulates therein a low-heat conductivity gas and which yields high heat insulating performance. High-melting point beads that have been foamed up to a prescribed expansion ratio with a gas of low thermal conductivity by using a resin that does not soften at the beads-foaming temperature and that has a low gas transmission rate are mixed with low-temperature foam beads to be foamed within a forming die, and the resultant mixture is filled in a beads forming die cavity and foamed by heating.
    Type: Application
    Filed: November 22, 2017
    Publication date: September 19, 2019
    Applicant: Mitsubishi Electric Corporation
    Inventors: Yusuke NAKANISHI, Yuta KUBO, Masaru IMAIZUMI, Kazushi KONO
  • Publication number: 20190256531
    Abstract: The present invention provides a compound represented by the general formula (Ia) or a pharmacologically acceptable salt thereof. In the general formula (Ia), two R moieties each independently represent a C1-3 alkyl group or the like; and R1, R2 and R3 each independently represent an optionally substituted linear or branched C1-4 alkyl group.
    Type: Application
    Filed: April 3, 2019
    Publication date: August 22, 2019
    Applicant: UBE INDUSTRIES, LTD.
    Inventors: Noriaki IWASE, Yasuhiro AGA, Shigeru USHIYAMA, Shigeyuki KONO, Hidetoshi SUNAMOTO, Takashi MATSUSHITA, Sayaka OGI, Satoshi UMEZAKI, Masahiro KOJIMA, Kazuhiro ONUMA, Yusuke SHIRAISHI, Makoto OKUDO, Tomio KIMURA
  • Publication number: 20190246054
    Abstract: Provided is an apparatus including: first and second photoelectric converting portions; a charge detecting portion; a transistor outputting a pixel signal first and second sampling and holding capacitors; an amplifier; and a controlling unit controlling gain in first and second mode. The pixel signal is one of: a first signal at time of resetting of charge; a second signal including a charge component of the first photoelectric converting portion and a noise component; and a third signal including the first component, a charge component of the second photoelectric converting portion and a noise component. In the first mode, the controlling unit uses a first gain. In the second mode, the controlling unit uses second gain to the first signal, third gain to the third signal of the first sampling and holding capacitor, and second gain to the third signal of the second sampling and holding capacitor.
    Type: Application
    Filed: January 30, 2019
    Publication date: August 8, 2019
    Inventors: Masahiro Kobayashi, Shoji Kono, Yusuke Yamashita
  • Publication number: 20190238774
    Abstract: A photoelectric conversion apparatus includes first and second signal lines, first and second circuits, and a switch. Signals based on electric charges generated in first and second photoelectric conversion portions are to be read out to the first and second signal lines, respectively. The first circuit includes a first input unit to which the first signal line is connected. The first circuit is configured to perform processing of a signal input to the first input unit, with a first gain. The second circuit includes a second input unit to which the second signal line is connected. The second circuit is configured to perform processing of a signal input to the second input unit. The switch is configured to perform switching between a connected state and a disconnected state between the first signal line and the second signal line.
    Type: Application
    Filed: January 23, 2019
    Publication date: August 1, 2019
    Inventors: Shoji Kono, Toru Koizumi, Hiroo Akabori, Yusuke Yamashita
  • Publication number: 20180282679
    Abstract: Provided is a cell culture apparatus capable of constructing cultured cells under an environment closer to that in a living body. The cell culture apparatus includes: a culture substrate (11) having a culture surface (11a) on which cells S are cultured; and a drive unit (12) configured to allow opening and closing of the culture substrate (11) between a closed form and an open form. The closed form is a form in which the culture substrate (11) forms a flow path having an internal volume with the culture surface (11) being an internal surface of the flow path. The open form is a form in which the culture surface (11a) of the culture substrate (11) is opened outward more than the culture surface (11a) of the culture substrate (11) in the closed form.
    Type: Application
    Filed: July 26, 2016
    Publication date: October 4, 2018
    Applicant: The Ritsumeikan Trust
    Inventors: Satoshi KONISHI, Takuya FUJITA, Koji HATTORI, Yusuke KONO
  • Publication number: 20180215782
    Abstract: The present invention has an object of providing a peptide synthesis method using a carrier capable of reversibly repeating the dissolved state and the insolubilized state, wherein the problem of an amino acid active species existing in the reaction system in de-protection reaction can be easily solved. The present invention provides a peptide synthesis method comprising the following steps: a step of condensing an N-Fmoc protected amino acid with a peptide having a C-terminal protected with a carrier which is crystallized according to a change of a composition of a dissolving solvent, in the presence of a condensing agent, to obtain an N-Fmoc-C-carrier protected peptide, a step of adding an alkylamine having 1 to 14 carbon atoms or hydroxyl amine to the reaction system, a step of de-protecting the N-terminal, and a step of changing the composition of the solvent dissolving the C-carrier protected peptide, to crystallize and separate the peptide.
    Type: Application
    Filed: March 2, 2016
    Publication date: August 2, 2018
    Inventors: Yusuke KONO, Hideaki SUZUKI, Susumu MUTO
  • Publication number: 20160333052
    Abstract: The purpose of the present invention is to provide a cross-linked peptide containing a novel non-peptide cross-linked structure, and a method for synthesizing the same. A cross-linked peptide having a novel non-peptide cross-linked structure, a useful intermediate for synthesizing the cross-linked peptide, and a method for synthesizing the novel cross-linked peptide and the intermediate are provided. The cross-linked peptide is characterized by having an —NR— bond in the cross-linked structure. By using the method for synthesizing the cross-linked peptide, a cross-link can be freely designed and an change can be freely made to a cross-link.
    Type: Application
    Filed: May 17, 2016
    Publication date: November 17, 2016
    Inventors: Yusuke KONO, Shuji Fujita, Hideaki Suzuki, Mari Okumoto, Takashi Nakae, Kazuhiro Chiba
  • Publication number: 20160333050
    Abstract: The purpose of the present invention is to provide a cross-linked peptide containing a novel non-peptide cross-linked structure, and a method for synthesizing the same. A cross-linked peptide having a novel non-peptide cross-linked structure, a useful intermediate for synthesizing the cross-linked peptide, and a method for synthesizing the novel cross-linked peptide and the intermediate are provided. The cross-linked peptide is characterized by having an —NR— bond in the cross-linked structure. By using the method for synthesizing the cross-linked peptide, a cross-link can be freely designed and an change can be freely made to a cross-link.
    Type: Application
    Filed: May 17, 2016
    Publication date: November 17, 2016
    Inventors: Yusuke KONO, Shuji FUJITA, Hideaki SUZUKI, Mari OKUMOTO, Takashi NAKAE, Kazuhiro CHIBA
  • Patent number: 9376467
    Abstract: The purpose of the present invention is to provide a cross-linked peptide containing a novel non-peptide cross-linked structure, and a method for synthesizing the same. A cross-linked peptide having a novel non-peptide cross-linked structure, a useful intermediate for synthesizing the cross-linked peptide, and a method for synthesizing the novel cross-linked peptide and the intermediate are provided. The cross-linked peptide is characterized by having an —NR— bond in the cross-linked structure. By using the method for synthesizing the cross-linked peptide, a cross-link can be freely designed and an change can be freely made to a cross-link.
    Type: Grant
    Filed: February 28, 2012
    Date of Patent: June 28, 2016
    Assignee: JITSUBO CO., LTD.
    Inventors: Yusuke Kono, Shuji Fujita, Hideaki Suzuki, Mari Okumoto, Takashi Nakae, Kazuhiro Chiba
  • Patent number: 9365615
    Abstract: The purpose of the present invention is to provide a cross-linked peptide containing a novel non-peptide cross-linked structure, and a method for synthesizing the same. A cross-linked peptide having a novel non-peptide cross-linked structure, a useful intermediate for synthesizing the cross-linked peptide, and a method for synthesizing the novel cross-linked peptide and the intermediate are provided. The cross-linked peptide is characterized by having an —NR— bond in the cross-linked structure. By using the method for synthesizing the cross-linked peptide, a cross-link can be freely designed and an change can be freely made to a cross-link.
    Type: Grant
    Filed: September 9, 2013
    Date of Patent: June 14, 2016
    Assignee: JITSUBO CO., LTD.
    Inventors: Yusuke Kono, Shuji Fujita, Hideaki Suzuki, Mari Okumoto, Takashi Nakae, Kazuhiro Chiba
  • Patent number: 9284348
    Abstract: Disclosed are a carrier for use for separation purpose and a method for separation of a compound which enable a chemical reaction to be performed in a liquid phase, enable a compound of interest to be separated from the liquid phase after the completion of the reaction readily, enable the separated compound to be evaluated by structural analysis or the like while the compound being bound to the carrier, and enable the compound to be separated from the carrier readily. A carrier for separation which has a reaction site capable of reacting with other compound on a benzene ring, and a long-chain group having a specified carbon atom(s) at each of the ortho-position and the para-position of the reaction site through an oxygen atom.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: March 15, 2016
    Assignee: JITSUBO Co., Ltd.
    Inventors: Kazuhiro Chiba, Shokaku Kim, Yusuke Kono
  • Publication number: 20150073121
    Abstract: The purpose of the present invention is to provide a cross-linked peptide containing a novel non-peptide cross-linked structure, and a method for synthesizing the same. A cross-linked peptide having a novel non-peptide cross-linked structure, a useful intermediate for synthesizing the cross-linked peptide, and a method for synthesizing the novel cross-linked peptide and the intermediate are provided. The cross-linked peptide is characterized by having an —NR— bond in the cross-linked structure. By using the method for synthesizing the cross-linked peptide, a cross-link can be freely designed and an change can be freely made to a cross-link.
    Type: Application
    Filed: September 9, 2013
    Publication date: March 12, 2015
    Applicant: JITSUBO Co., Ltd.
    Inventors: Yusuke Kono, Shuji Fujita, Hideaki Suzuki, Mari Okumoto, Takashi Nakae, Kazuhiro Chiba
  • Publication number: 20140107319
    Abstract: Disclosed are a carrier for use for separation purpose and a method for separation of a compound which enable a chemical reaction to be performed in a liquid phase, enable a compound of interest to be separated from the liquid phase after the completion of the reaction readily, enable the separated compound to be evaluated by structural analysis or the like while the compound being bound to the carrier, and enable the compound to be separated from the carrier readily. A carrier for separation which has a reaction site capable of reacting with other compound on a benzene ring, and a long-chain group having a specified carbon atom(s) at each of the ortho-position and the para-position of the reaction site through an oxygen atom.
    Type: Application
    Filed: December 20, 2013
    Publication date: April 17, 2014
    Applicants: JITSUBO Co., Ltd., National University Corporation, Tokyo University of Agriculture and Technology
    Inventors: Kazuhiro Chiba, Shokaku Kim, Yusuke Kono
  • Patent number: 8633298
    Abstract: A carrier for use for separation purpose and a method for separation of a compound enable a chemical reaction to be performed in a liquid phase, a compound of interest to be separated from the liquid phase after the completion of the reaction readily, the separated compound to be evaluated by structural analysis or the like while the compound is being bound to the carrier, and the compound to be separated from the carrier readily. A carrier for separation is also provided which has a reaction site capable of reacting with other compound(s) on a benzene ring, and a long-chain group having a specified carbon atom(s) at each of the ortho-position and the para-position of the reaction site through an oxygen atom.
    Type: Grant
    Filed: September 20, 2006
    Date of Patent: January 21, 2014
    Assignee: Jitsubo Co., Ltd.
    Inventors: Kazuhiro Chiba, Shokaku Kim, Yusuke Kono
  • Publication number: 20130345393
    Abstract: The purpose of the present invention is to provide a cross-linked peptide containing a novel non-peptide cross-linked structure, and a method for synthesizing the same. A cross-linked peptide having a novel non-peptide cross-linked structure, a useful intermediate for synthesizing the cross-linked peptide, and a method for synthesizing the novel cross-linked peptide and the intermediate are provided. The cross-linked peptide is characterized by having an —NR— bond in the cross-linked structure. By using the method for synthesizing the cross-linked peptide, a cross-link can be freely designed and an change can be freely made to a cross-link.
    Type: Application
    Filed: February 28, 2012
    Publication date: December 26, 2013
    Applicant: JITSUBO Co., Ltd.
    Inventors: Yusuke Kono, Shuji Fujita, Hideaki Suzuki, Mari Okumoto, Takashi Nakae, Kazuhiro Chiba
  • Patent number: 8344103
    Abstract: A solvent system which comprises two or more single organic solvents or two or more mixed organic solvents, characterized in that the state of the solvent system can be reversibly changed, with changing temperature conditions, from one state which is a homogeneously compatibilized mixed solvent system in which the two or more single or more mixed organic solvents constituting the solvent system have been homogeneously compatibilized and mixed to the other state which is a separated solvent system made up of two or more separated phases respectively consisting mainly of the two or more single or mixed organic solvents constituting solvent system, and that when the solvent system is the homogeneously mixed solvent system, a chemical component which is soluble in only one of the single or mixed organic solvents can be evenly dissolved in the system; and a process for producing a compound with the solvent system.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: January 1, 2013
    Assignee: Japan Science and Technology Agency
    Inventors: Kazuhiro Chiba, Yusuke Kono
  • Patent number: 8293948
    Abstract: A reagent for organic synthesis with which a chemical reaction can be conducted in a liquid phase and unnecessary compound(s) can be easily separated at low cost from the liquid phase after completion of the reaction. The reagent for organic synthesis reversibly changes from a liquid-phase state to a solid-phase state with changes in solution composition and/or solution temperature, and is for use in organic synthesis reactions. This reagent for organic syntheses facilitates process development. With the reagent, research on and development of, e.g., medicines through, e.g., compound library synthesis, etc. can be accelerated. It can hence contribute to technical innovations in the biochemical industry and chemical industry.
    Type: Grant
    Filed: January 9, 2012
    Date of Patent: October 23, 2012
    Assignee: Jitsubo Co., Ltd.
    Inventors: Kazuhiro Chiba, Shokaku Kim, Yusuke Kono
  • Publication number: 20120108788
    Abstract: A reagent for organic synthesis with which a chemical reaction can be conducted in a liquid phase and unnecessary compound(s) can be easily separated at low cost from the liquid phase after completion of the reaction. The reagent for organic synthesis reversibly changes from a liquid-phase state to a solid-phase state with changes in solution composition and/or solution temperature, and is for use in organic synthesis reactions. This reagent for organic syntheses facilitates process development. With the reagent, research on and development of, e.g., medicines through, e.g., compound library synthesis, etc. can be accelerated. It can hence contribute to technical innovations in the biochemical industry and chemical industry.
    Type: Application
    Filed: January 9, 2012
    Publication date: May 3, 2012
    Applicant: JITSUBO Co., Ltd.
    Inventors: Kazuhiro Chiba, Shokaku Kim, Yusuke Kono
  • Patent number: 8093435
    Abstract: A reagent for organic synthesis with which a chemical reaction can be conducted in a liquid phase and unnecessary compound(s) can be easily separated at low cost from the liquid phase after completion of the reaction. The reagent for organic synthesis reversibly changes from a liquid-phase state to a solid-phase state with changes in solution composition and/or solution temperature, and is for use in organic synthesis reactions. This reagent for organic syntheses facilitates process development. With the reagent, research on and development of, e.g., medicines through, e.g., compound library synthesis, etc. can be accelerated. It can hence contribute to technical innovations in the biochemical industry and chemical industry.
    Type: Grant
    Filed: February 19, 2007
    Date of Patent: January 10, 2012
    Assignee: JITSUBO Co., Ltd.
    Inventors: Kazuhiro Chiba, Shokaku Kim, Yusuke Kono