Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.

Abstract: A toner cartridge includes a chamber containing toner, a feeding portion configured to feed the toner toward an opening in the toner cartridge, and a pump configured to discharge the toner through the opening to outside of the toner cartridge, the pump being configured to move the toner by changing pressure inside of the toner cartridge relative to pressure outside of the toner cartridge. A rotatable coupling is configured to receive a rotational force from outside of the toner cartridge, the coupling being operatively connected to the feeding portion and the pump so as to transmit the rotational force to the feeding portion and the pump to thereby rotate the feeding portion and drive the pump.

Abstract: The invention provides a production process allowing more high-yield and efficient synthesis of key intermediates (compound (2i) or a salt thereof, and compound (1g)) for production of E7090, which is useful as an FGFR inhibitor.

Abstract: Provided is compound (3d) or a salt thereof, wherein the content of compound (IM-7) is 0.48 mass % or lower.

Abstract: A control unit of an information processing device acquires a request to add an item to a vehicle, acquires first information that is information according to whether the vehicle has a structure for adding an item, determining a fee for adding the item to the vehicle based on the one piece of information and the information about the item, and outputting the information about the fee.

Abstract: A motor control method that can suppress a mover from vibrating when the mover is stopped is provided. A motor control method includes a command step of generating and outputting a second operation command for operating motor, based on the vibration cycle of mover and on the timing when the operation of motor based on the first operation command for operating motor that moves mover ends, and a drive step of generating and outputting a drive signal for operating motor based on the first operation command and the second operation command.

Abstract: An information processing device includes a control unit that executes: obtaining a request to add an item to a vehicle; obtaining first information that is information depending on whether the vehicle has a structure for adding an item; determining a factory that provides a service for adding the item to the vehicle based on the first information and information about the item; and outputting information about the factory.

Abstract: A fluorine-containing elastomer composition comprising 0.4 to 4.0 parts by weight of a pigment that is a perylene-based compound, a naphthalenecarboxamide-based compound, a pyrimidinetrione-based compound, or a benzimidazolone-based compound, and 0.2 to 5.0 parts by weight of a bisamidoxime compound or 2,2-bis(3-amino-4-hydroxyphenyl)hexafluoropropane, based on 100 parts by weight of a fluorine-containing elastomer having a copolymer composition of (A) 60.0 to 80.0 mol % of tetrafluoroethylene, (B) 19.8 to 39.8 mol % of perfluoro(lower alkyl vinyl ether) or perfluoro(lower alkoxy lower alkyl vinyl ether), and (C) 0.2 to 5.0 mol % of a perfluoro unsaturated nitrile compound.

Abstract: An aqueous developer for a flexographic printing plate capable of maintaining good developability and suppressing aggregation of a dispersion in the developer diluted with water after repeated use, and a manufacturing method of a flexographic printing plate using the same, are provided.

Abstract: Motor control system (10) includes position detection device (14), controller (12), and motor control device (16). Motor control device (16) includes a shift amount calculation unit that calculates a predicted arrival position of moving unit (50) based on positional information indicating a position of moving unit (50) detected by using position detection device (14) and distance information indicating a future moving distance of moving unit (50) based on an operation command, calculates a shift amount between the predicted arrival position and a target position of moving unit (50), and outputs information indicating the shift amount between the predicted arrival position and the target position.

Abstract: A component supply device includes: a picker base on which a component is to be loaded; a supplier that picks up the component loaded on the picker base and supplies the component to a predetermined position; a detector that detects the component loaded on the picker base; and a hardware processor that determines a state of the component loaded on the picker base, on a basis of information detected by the detector, wherein the hardware processor determines whether the component is a component that is pickable or a component that is unpickable by the supplier on a basis of the state of the component, and calculates an operation amount for adjusting the component that is unpickable to a pickable state and adjusts only a state of the component that is unpickable by an adjuster on a basis of the calculated operation amount.

Abstract: The present invention provides a pharmaceutical composition comprising an antibody which binds specifically to human TLR7 or monkey TLR7 and does not bind to mouse TLR7 or rat TLR7, and has an activity of inhibiting a function of human TLR7 or monkey TLR7, and the like.

Abstract: A picking device includes: a workpiece holder in which a plurality of workpieces is stacked; a light receiver that receives reflected light from a workpiece stacked in the workpiece holder; a mover that relatively moves the light receiver with respect to the workpiece in such a manner that a distance between the light receiver and the workpiece is adjustable; an arm that picks the workpiece; a first hardware processor that calculates a distance between the light receiver and at least one workpiece among the plurality of workpieces; a second hardware processor that specifies a workpiece as a picking target among the plurality of workpieces or a region where the workpiece exists; and a third hardware processor that adjusts a distance between the light receiver and the workpiece calculated by the first hardware processor by controlling the mover in the region specified by the second hardware processor.

Abstract: The present invention provides a pharmaceutical composition comprising an antibody which binds specifically to human TLR7 or monkey TLR7 and does not bind to mouse TLR7 or rat TLR7, and has an activity of inhibiting a function of human TLR7 or monkey TLR7, and the like.

Abstract: An object is captured in an image taken by the camera. An external shape of the object is recognized from the image. An internal shape of the object is recognized from the image. Parts information of the object is then determined, using a result of the recognition of the external shape and/or a result of recognition of the internal shape.

Abstract: The present invention is intended to provide a novel biomarker for detecting arteriosclerosis-related disease or for evaluating the stage of progression of arteriosclerosis, and specifically, the present invention relates to a marker for detecting arteriosclerosis-related disease or for evaluating the stage of progression of arteriosclerosis, comprising an NPC2 (Niemann-Pick disease type C2) protein and/or an IGFBP7 (Insulin-like growth factor-binding protein 7) protein.

Abstract: The present invention is intended to provide a novel biomarker capable of detecting aortic aneurysm with high sensitivity, and specifically, the present invention relates to a detection marker of aortic aneurysm, comprising an NPC2 (Niemann-Pick disease type C2) protein and/or an IGFBP7 (Insulin-like growth factor-binding protein 7) protein.

Abstract: The present invention provides a novel antibody targeting TLR9.

Abstract: The present invention provides a pharmaceutical composition comprising an antibody which binds specifically to human TLR7 or monkey TLR7 and does not bind to mouse TLR7 or rat TLR7, and has an activity of inhibiting a function of human TLR7 or monkey TLR7, and the like.

Abstract: An image forming apparatus includes: a photoconductor; a transfer portion; a photoconductor cleaner that removes residual toner from a surface of the photoconductor; and a first processor that forms a toner patch on the surface of the photoconductor. When the toner patch passes the transfer portion, the transfer portion makes the toner patch stay on the surface of the photoconductor such that toner of the toner patch is able to be supplied to the photoconductor cleaner. The first processor further determines an amount of toner for the toner patch with reference to a circumferential distance the photoconductor travels for a predetermined period of time.