Abstract: An object of the present invention is to provide a pharmaceutical composition, particularly a compound suitable for preventing and/or treating an inflammatory disease and/or a neurodegenerative disease. The present inventors accomplished the present invention by conducting intensive studies to find a compound having an inhibitory effect on NLRP3 inflammasome activation, with the result that a substituted triazine compound is found to have the inhibitory effect on NLRP3 inflammasome activation. The substituted triazine compound of the present invention is expected to serve as a preventive and/or therapeutic drug for an inflammatory disease and/or a neurodegenerative disease.

Abstract: When a server system detects that a first player character and a second player character have entered a given involved situation in a common game space, the server system performs gameplay control to a player terminal of the first player character and a player terminal of the second player character according to gameplay specs of each of the player terminals in the involved situation. As the gameplay control, the server system generates a special game space including an object model of a grade appropriate for implementing a play experience as pleasant as possible with the highest possible quality allowed by the gameplay specs, and generates and displays a game space image and a gameplay image in the special game space.

Abstract: A vehicle body rear structure includes: a rear wheel house; a rear cross member located on a vehicle width direction inner side of a lower portion of the rear wheel house and extending in a vehicle width direction; a pillar extending upward from an upper portion of the rear wheel house; a wheel house reinforcing member extending along the rear wheel house and connecting between the rear cross member and the pillar; a retractor functioning as a seat belt winding device; and a bracket configured to fix the retractor to a vehicle body. The bracket has one end portion connected to the wheel house reinforcing member. The bracket has another portion extending from the one end portion in the vehicle forward direction or in the vehicle rearward direction and connected to the rear wheel house.

Abstract: A first belt cord made of organic fibers of a spirally wound belt layer extends at an angle of equal to or less than 5° relative to a tire equatorial plane, a second belt cord made of organic fibers of a zigzag belt layer extends at an inclination of an angle of 2° to 45° relative to the tire equatorial plane, to folding back points where the second belt cord is folded back at each width directional end edge of the zigzag belt layer, and a relation of N95>N50 is satisfied. N50 is the number of stacked belt layers of the spirally wound belt layers, at 50% of half the length of a maximum belt width of belt layers from the tire equatorial plane. N95 is the number of stacked belt layers of the spirally wound belt layers, at 95% of half the length of the maximum belt.

Abstract: A first color electrodes and a third color electrodes may be arrayed in an alternating manner following a first direction, and may also be arrayed in an alternating manner following a second direction that is orthogonal to the first direction. A first color electrodes that are situated in a first display region and a second display region may be arrayed at a first pitch following each of the first direction and the second direction. The first color electrodes and the third color electrodes that are situated in the second display region may be arrayed so as to alternate between a second pitch and a third pitch, following each of the first direction and the second direction. The second pitch may differ from the third pitch.

Abstract: The present invention provides epitope peptides which are derived from SARS-CoV-2 proteins and have the ability to induce cytotoxic T cells. The present invention also provides polynucleotides encoding the peptides, antigen-presenting cells that present the peptides, and cytotoxic T cells that target the peptides, and methods of inducing the antigen-presenting cells or CTLs. The present invention further provides compositions and pharmaceutical compositions containing them as active ingredients. Moreover, the present invention provides methods of treating and/or preventing coronavirus infectious diseases, and/or methods of suppressing the aggravation of coronavirus infectious diseases by using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells, or pharmaceutical compositions of the present invention. The present invention also provides methods of inducing an immune response against coronavirus infection.

Abstract: A sensor device includes a sensor element, a substrate, and a bonding wire. Over the substrate, provided is the sensor element. The bonding wire forms at least part of a connection path that electrically connects the sensor element and the substrate together. The bonding wire is provided to connect two connection surfaces that intersect with each other.

Abstract: An electronic device includes a substrate, a plurality of first electrodes located on the substrate, a plurality of organic layers located on the first electrodes, and a second electrode that is located on the organic layers and that spreads so as to overlap the plurality of the first electrodes in planar view. The second electrode located in the second display area has a plurality of apertures formed in such positions as not to overlap the first electrodes in planar view and is divided into a plurality of unit regions on the basis of the plurality of first electrodes. The plurality of unit regions includes aperture regions including the apertures and non-aperture regions not including the apertures.

Abstract: An electrochemical device includes: an electrode body including a positive electrode, a negative electrode, and a separator disposed between the positive electrode and the negative electrode; and an electrolyte containing a lithium salt. The negative electrode includes a negative current collector and a negative electrode mixture layer supported on the negative current collector. The negative electrode mixture layer contains a negative electrode active material that is reversibly doped with lithium ions, and the negative current collector has substantially no through-hole. A specific surface area of the negative electrode mixture layer is in a range from 30 m2/g to 60 m2/g, inclusive, and in a discharged state, a potential of the negative electrode is less than or equal to 0.2 V with respect to a Li counter electrode.

Abstract: The imaging device includes: a modulator configured to modulate a light intensity in accordance with a real pattern; an image sensor configured to create a sensor image in accordance with the modulated light; and a micro lens array including a plurality of micro lenses arranged to correspond to a plurality of pixels of the image sensor. The imaging device has a distribution property of a relative positional difference amount between a center position of a light receiver of each pixel of the plurality of pixels and a center position of each micro lens of the plurality of micro lenses of the micro lens array in a plane of the image sensor. This property has at least one point or more with a changing difference value of the difference amount between the adjacent pixels from a positive value to a negative value or from a negative value to a positive value.

Abstract: An object of the invention is to provide a technique of performing alignment with high accuracy between a plurality of sensors even when a visual field overlapping region at the time of installation of the sensors is small in a case of imaging a subject using the plurality of sensors. An integrated image generation apparatus according to the invention generates a first pseudo visual field image that is able to be acquired by a first sensor in a first pseudo visual field generated by moving a relative position between the subject and the first sensor, and performs the alignment between the first pseudo visual field image and a second sensor image.

Abstract: A three-dimensional data processing device according to the present invention detects each of a first area at a first time and a second area at a second time as an area including a subject in three-dimensional data, and calculates a difference of the three-dimensional data between the first time and the second time using coordinate transformation between the first area and the second area.

Abstract: The present invention provides epitope peptides which are derived from SARS-CoV-2 proteins and have the ability to induce cytotoxic T cells. The present invention also provides polynucleotides encoding the peptides, antigen-presenting cells that present the peptides, and cytotoxic T cells that target the peptides, and methods of inducing the antigen-presenting cells or CTLs. The present invention further provides compositions and pharmaceutical compositions containing them as active ingredients. Moreover, the present invention provides methods of treating and/or preventing coronavirus infectious diseases, and/or suppressing the aggravation of coronavirus infectious diseases by using the peptides, polynucleotides, antigen-presenting cells, cytotoxic T cells, or pharmaceutical compositions of the present invention. The present invention also provides methods of inducing an immune response against coronavirus infection.

Abstract: An imaging device includes a modulator, a first grating pattern constituted by a plurality of lines, and a second grating pattern having a phase deviating from a phase of the first grating pattern, and modulates light intensity. The imaging device receives a first image signal output by the first grating pattern and a second image signal output by the second grating pattern, calculates difference data and a range of a difference between the first image signal and the second image signal, generates and sets a data conversion parameter at a regular interval from the difference data that is continuously input on the basis of the range of the difference and the difference data, generates compression image data by using the difference data and the data conversion parameter, compresses the generated compression image data, and includes information indicating the range of the difference into the compressed data.

Abstract: Provided is a cosmetic liquid applicator that allows easy determination as to the completion state of replacement of an application liquid tank. The cosmetic liquid applicator includes a front barrel to which an application liquid tank for storing a liquid cosmetic to be fed to an applying part is attached and a rear barrel attached to the front barrel to cover the application liquid tank. The front barrel has on its peripheral surface a male threaded portion and a first engagement portion formed in the circumferential direction and located in the rear of the male threaded portion while the rear barrel has on its inner circumferential surface a female threaded portion to mate with the male threaded portion and a second engagement portion to be engaged with the first engagement portion.

Abstract: Provided is a charged particle beam device that can impart a function of an energy filter to even a small BSE detector. The charged particle beam device includes a fluorescent substance that converts charged particles generated by irradiation of a sample with a charged particle beam into light; a detector that detects the light emitted from the fluorescent substance; a light guide element for guiding the light from the fluorescent substance to the detector; a light amount adjuster that adjusts the amount of light that is received by the detector through the fluorescent substance and the light guide element; and a control unit that controls the light amount adjuster.

Abstract: An electronic device may include a substrate, a plurality of first electrodes located on a first surface of the substrate, a plurality of organic layers located on top of the first electrodes, and a second electrode, located on top of the organic layers, that spreads so as to overlap the plurality of first electrodes in planar view. The second electrode may include a plurality of unit regions demarcated based on the plurality of first electrodes and a plurality of apertures, located in the unit regions, that do not overlap the first electrodes in planar view. Each unit region includes a unit region center point located in a center of the unit region in planar view. Each aperture includes an aperture center point located in a center of the aperture in planar view.

Abstract: An interframe difference processor 206 generates a difference image between frames of a sensor image, and an image processor 208 generates distance information indicating a distance to a photographic subject on the basis of calculation of a difference image and a developing pattern 1101. Thus, since a video display apparatus 101 generates the difference image between the frames of the sensor image, it is possible to realize a distance measuring apparatus capable of reducing an influence of a background and generating distance information with high accuracy.

Abstract: A modulator has a first grating pattern, and a second grating pattern having a phase shifted from the first grating pattern; a sensor processor receives a first image signal outputted by the first grating pattern, and a second image signal outputted by the second grating pattern; a difference processor calculates a difference between the first image signal and the second image signal; and a compression processor 3005 contains information that indicates a range of the difference to first compression image data. Those make it possible to reduce a data amount of images capable of focus adjustment etc. from later, and to lead to reduction in costs of a storage apparatus.

Abstract: A negative electrode for an electrochemical device includes a negative electrode core material and a negative electrode material layer supported on the negative electrode core material. The negative electrode material layer contains a carbon material. A surface layer portion of the negative electrode material layer includes a first layer containing lithium carbonate and a second layer containing a solid electrolyte. At least a portion of the second layer covers at least a portion of the surface of the carbon material with the first layer interposed therebetween.