Abstract: A droplet discharge device for discharging a droplet into recess parts of a storage vessel includes a storage vessel, a discharge head configured to insert a discharge surface into a recess part and discharge droplets while moving in two horizontal directions, a mounting table, a vertical position adjusting part configured to change a relative vertical position between the head and table, a vertical position adjustment control part configured to control the adjusting part, a horizontal position detecting part configured to detect a horizontal position of the storage vessel, and a target position detecting part configured to detect, before starting discharge, a distance from a vertical reference height to a discharge target surface, wherein the control part controls, based on the detected distance, the vertical position of the head or table during the discharge such that a discharge height of the discharge surface relative to the discharge target surface stays constant.

Abstract: An object of the present invention is to provide a technique for precisely arranging nerve cells on a substrate while suppressing the migration of nerve cells. A manufacturing method for a substrate on which nerve cells are arranged is provided, the method including a step of arranging, on a substrate, a plurality of liquid droplets containing nerve cells by an inkjet method to form one or a plurality of liquid pools, the substrate having a region in which a cell adhesive material is arranged and a region in which a cell non-adhesive material is arranged; and a step of incubating the liquid pool until the nerve cells sediment and temporarily adhere onto the substrate to form a cell aggregate. The diameter per one liquid pool is 500 ?m or less, and the density of nerve cells per one liquid pool is 105 cells/cm2 or more.

Abstract: Provided is an in vivo liquid flow promotion device capable of safely and effectively promoting a liquid flow in a desired direction. The in vivo liquid flow promotion device includes an ultrasonic oscillator that generates an ultrasonic wave, and an acoustic flow generator that adjusts the phase of an ultrasonic wave generated by an ultrasonic oscillator to focus the ultrasonic wave on a predetermined position, and that allows to generate an acoustic flow in in vivo fluid at a focused position by a pressure distribution generated in accordance with the phase.

Abstract: What is provided is a liquid droplet forming apparatus capable of stably ejecting dispersion liquid, as liquid droplets, containing settling particles having constant concentration. A liquid droplet forming apparatus includes an ejection head that has a liquid chamber storing liquid containing settling particles and that ejects a liquid droplet of the liquid, stirrer for stirring the liquid held in the liquid chamber, posture controller for controlling a posture of the stirrer, and a control unit that controls operations of the ejection head, the stirrer, and the posture controller, in which the stirrer includes a tube-like member inserted into the liquid chamber, and a liquid feeding portion that sucks or discharges the liquid stored in the liquid chamber via the tube-like member, and the posture controller controls one or both of the position and the direction in which the stirrer sucks and discharges the liquid in the liquid chamber.

Abstract: A gel precursor composition causative of no apprehension about exhibiting cytotoxicity can be made. A method for producing a gel causative of no apprehension about exhibiting cytotoxicity, using the gel precursor composition can be performed. One of the present embodiments is a gel precursor composition including: a biocompatible polymer; a crosslinking agent to be activated by a specific substance; and a photoresponsive compound bound to the specific substance, or encompassing the specific substance.

Abstract: A liquid droplet forming device for stably forming and ejecting a liquid droplet of a dispersion liquid containing settling particles includes an ejection head that ejects a liquid droplet of a liquid containing settling particles, and a control unit. The control unit controls a behavior of the ejection head by supplying an electrical signal. The ejection head includes a liquid holding portion that holds the liquid, a film-like member that has an ejection hole for ejecting the liquid droplet and that forms a liquid chamber, which holds the liquid, together with the liquid holding portion, and vibration applying means for vibrating the film-like member based on the electrical signal. The electrical signal includes an ejection signal for forming the liquid droplet by vibrating the film-like member, a stirring signal for vibrating the film-like member and a micro-vibration signal.

Abstract: A liquid droplet forming device for stably forming and ejecting a liquid droplet of a dispersion liquid containing settling particles includes an ejection head that ejects a liquid droplet of a liquid containing settling particles, and a control unit. The control unit controls a behavior of the ejection head by supplying an electrical signal. The ejection head includes a liquid holding portion that holds the liquid, a film-like member that has an ejection hole for ejecting the liquid droplet and that forms a liquid chamber, which holds the liquid, together with the liquid holding portion, and vibration applying means for vibrating the film-like member based on the electrical signal. The electrical signal includes an ejection signal for forming the liquid droplet by vibrating the film-like member, a stirring signal for vibrating the film-like member and a micro-vibration signal.

Abstract: A method for manufacturing a cell culture substrate in which cells are fixed via a hydrogel on a surface of a substrate includes forming a film of a first liquid on the surface of the substrate, and ejecting droplets of a second liquid onto the film.

Abstract: A droplet discharge device for discharging a droplet into recess parts of a storage vessel includes a storage vessel, a discharge head configured to insert a discharge surface into a recess part and discharge droplets while moving in two horizontal directions, a mounting table, a vertical position adjusting part configured to change a relative vertical position between the head and table, a vertical position adjustment control part configured to control the adjusting part, a horizontal position detecting part configured to detect a horizontal position of the storage vessel, and a target position detecting part configured to detect, before starting discharge, a distance from a vertical reference height to a discharge target surface, wherein the control part controls, based on the detected distance, the vertical position of the head or table during the discharge such that a discharge height of the discharge surface relative to the discharge target surface stays constant.

Abstract: A droplet discharge device for discharging a droplet into one or more droplet storage parts of a storage vessel; the droplet discharge device including: a droplet discharge part configured to discharge the droplet in a predetermined amount from a nozzle hole of the droplet discharge part; a storage vessel holding part configured to hold the storage vessel; a mover part configured to move the droplet discharge part relative to the storage vessel that is held by the storage vessel holding part; and a detecting part configured to detect a shape of a surface of the storage vessel that is held by the storage vessel holding part.

Abstract: (Object) To improve the accuracy of the placement of liquid droplets. (Means of Achieving the object) A liquid droplet discharging method is performed by a liquid droplet discharging apparatus configured to discharge a liquid droplet from a nozzle hole formed in a film-like member, the liquid droplet discharging method including positioning the nozzle hole inside a recessed portion provided in a container; and discharging the liquid droplet from the nozzle hole positioned inside the recessed portion.

Abstract: Provided is a liquid droplet discharging apparatus that can maintain stable discharging even when a liquid containing particles or cells adheres to a nozzle surface.

Abstract: A liquid discharge apparatus includes a liquid discharge unit. The liquid discharge unit includes a liquid chamber member defining a liquid holding portion to hold a liquid, a film having a nozzle hole from which the liquid is discharged and a surface facing the liquid holding portion, and a holder supporting the film. The surface of the film has a contact angle with water of less than 90 degrees.

Abstract: An object of the present invention is to provide a technique for precisely arranging nerve cells on a substrate while suppressing the migration of nerve cells. A manufacturing method for a substrate on which nerve cells are arranged is provided, the method including a step of arranging, on a substrate, a plurality of liquid droplets containing nerve cells by an inkjet method to form one or a plurality of liquid pools, the substrate having a region in which a cell adhesive material is arranged and a region in which a cell non-adhesive material is arranged; and a step of incubating the liquid pool until the nerve cells sediment and temporarily adhere onto the substrate to form a cell aggregate. The diameter per one liquid pool is 500 ?m or less, and the density of nerve cells per one liquid pool is 105 cells/cm2 or more.

Abstract: A liquid discharge head includes a nozzle plate including a plurality of nozzles from each of which a liquid is discharged, and a channel member including a plurality of pressure chambers respectively communicating with the plurality of nozzles. The channel member includes a side wall in each of the plurality of pressure chambers, the side wall is perpendicularly bonded to the nozzle plate, a thickness of the side wall increases toward the nozzle plate, and the nozzle plate includes a flat surface in a periphery of each of the plurality of nozzles on a surface of the nozzle plate facing one of the plurality of pressure chambers.

Abstract: A liquid discharging device includes: a recording head that has nozzles discharging liquid, and forms an image on a target surface with the liquid while performing scanning of the target surface for multiple times; a moving unit that moves the recording head in main-scanning direction while making the head discharge liquid, and moves the head in sub-scanning direction after the head has discharged liquid; a drive waveform applying unit that applies a drive waveform to the respective nozzles; a temperature detecting unit that detects temperature about the head; a correcting unit that corrects drive waveform based on detected temperature; and a control unit that, when temperature about the head changes from first temperature to second temperature, performs control in such a way that, during the multiple scans, use of second-type drive waveform corresponding to the second temperature gradually increases against use of first-type drive waveform corresponding to the first temperature.

Abstract: A liquid discharging device includes: a recording head that has nozzles discharging liquid, and forms an image on a target surface with the liquid while performing scanning of the target surface for multiple times; a moving unit that moves the recording head in main-scanning direction while making the head discharge liquid, and moves the head in sub-scanning direction after the head has discharged liquid; a drive waveform applying unit that applies a drive waveform to the respective nozzles; a temperature detecting unit that detects temperature about the head; a correcting unit that corrects drive waveform based on detected temperature; and a control unit that, when temperature about the head changes from first temperature to second temperature, performs control in such a way that, during the multiple scans, use of second-type drive waveform corresponding to the second temperature gradually increases against use of first-type drive waveform corresponding to the first temperature.

Abstract: A liquid droplet ejecting head is disclosed, including a nozzle hole which ejects liquid droplets; an ejecting liquid chamber which is in communication with outside via the nozzle hole and which contains an ejecting liquid to be the liquid droplets; a pressure generating unit which generates pressure within the ejecting liquid chamber; a temperature detecting unit which detects temperature at a location at which is arranged a temperature measuring resistive body; and a pressure control unit which controls an output of the pressure generating unit based on detected results of the temperature detecting unit, wherein the pressure generating unit is configured to increase pressure within the ejecting liquid chamber, so that the ejecting liquid within the ejecting liquid chamber is ejected from the nozzle hole as the liquid droplets, and wherein the temperature measuring resistive body is arranged at the ejecting liquid chamber forming member.

Abstract: A liquid droplet ejecting head is disclosed, including a nozzle hole which ejects liquid droplets; an ejecting liquid chamber which is in communication with outside via the nozzle hole and which contains an ejecting liquid to be the liquid droplets; a pressure generating unit which generates pressure within the ejecting liquid chamber; a temperature detecting unit which detects temperature at a location at which is arranged a temperature measuring resistive body; and a pressure control unit which controls an output of the pressure generating unit based on detected results of the temperature detecting unit, wherein the pressure generating unit is configured to increase pressure within the ejecting liquid chamber, so that the ejecting liquid within the ejecting liquid chamber is ejected from the nozzle hole as the liquid droplets, and wherein the temperature measuring resistive body is arranged at the ejecting liquid chamber forming member.