Abstract: A pH management system of a liquid chromatograph includes a pH meter that measures a pH value of a mobile phase in the liquid chromatograph, and a warner that presents a warning in a case where it is determined that a pH value measured in the pH meter is different from a set pH value, or that the pH value measured in the pH meter deviates from the set pH value and an error rate exceeds a predetermined error rate, when the pH value measured in the pH meter and the set pH are compared to each other.

Abstract: A pH management system of a liquid chromatograph includes a pH meter that measures a pH value of a mobile phase in the liquid chromatograph, and a warner that presents a warning in a case where it is determined that a pH value measured in the pH meter is different from a set pH value, or that the pH value measured in the pH meter deviates from the set pH value and an error rate exceeds a predetermined error rate, when the pH value measured in the pH meter and the set pH are compared to each other.

Abstract: A chromatographic data processing device, data processing method, and chromatographic analysis system. When chromatographic analysis is performed, the data processing device obtains 3D data for time, wavelength, and strength from the PDA, and finds the assay value for the target component in the liquid sample by processing said data. If the peak top strength of the target component falls outside of the dynamic range, a dilution ratio for the liquid sample is determined by calculating the peak top strength of the target component using the ratio of the strength at the peak top wavelength on the spectrum for each point in time belonging to the peak to the strength of a separate wavelength.

Abstract: A chromatographic data processing device, data processing method, and chromatographic analysis system. When chromatographic analysis is performed, the data processing device obtains 3D data for time, wavelength, and strength from the PDA, and finds the assay value for the target component in the liquid sample by processing said data. If the peak top strength of the target component falls outside of the dynamic range, a dilution ratio for the liquid sample is determined by calculating the peak top strength of the target component using the ratio of the strength at the peak top wavelength on the spectrum for each point in time belonging to the peak to the strength of a separate wavelength.

Abstract: A mobile phase supply device comprises an aqueous path including a first delivery pump for delivering an aqueous mobile phase, an organic solvent path including a second delivery pump for delivering an organic solvent mobile phase, and a mixer for mixing mobile phases from the aqueous path and the organic solvent path, and supplying the mixture to an analysis path of a liquid chromatograph. A flow resistance between the second delivery pump and the mixer is greater than a flow resistance between the first delivery pump and the mixer.

Abstract: An screening method and apparatus for online identification of a reactive compound bonding with a target compound includes a first dimension analysis step whereby a sample including a target compound and a reactive compound are injected together into a sample injection port. The sample is led to a first dimension column using a first dimension mobile phase and is separated into components. An isolation step isolates the sample portion into a loop passage. A reactive compound concentration step includes leading the reaction products into a trap column that selectively traps the reactive compound while dissociating it from the reaction products isolated by the isolation step. A second dimension analysis step leads the sample trapped in the trap column to a second dimension column using a second dimension mobile phase.

Abstract: A two-dimensional liquid chromatograph includes a first-dimension separation channel for guiding a sample injected from a sample injection part to a first-dimension analysis column using a first-dimension analysis mobile phase for separation; two trap columns; an analysis channel for guiding components retained in the trap columns to a second-dimension analysis column using a second-dimension analysis mobile phase for analysis; and a channel switching mechanism. The switching mechanism connects the first-dimension separation channel to one of the trap columns and connecting the analysis channel to the other of the trap columns, and also switches connections between the trap columns and the channels.

Abstract: A reaction tank 15 for heating a sample solution containing glycoprotein in an alkali solution to separate sugar chains, and two cartridges 17a and 17b filled with ion exchange resin are provided, and the sample solution transported from the reaction tank 15 is subjected to neutralization treatment by passing the sample solution through the cartridges. The cartridges 17a and 17b are connected in parallel by two flow channel switching valves 16a and 16b. By switching the valves 16a and 16b, selection of a cartridge to be used for the neutralization treatment is made, and at the same time, acid and water are passed through the cartridge which is not in use, in order to allow regeneration of the ion exchange resin in the cartridge.

Abstract: Different lectins are immobilized in four columns, respectively. A sample containing a sugar chain is injected from a sample injection section, sent to one of the columns through a first flow path switching valve and a second or third flow path switching valve. Then, an eluate of the column is sent to a detector through a fourth flow path switching valve and is detected. Simultaneously, a cleaning solution is sent to one of columns, which differs from the column performing the analysis, through the first flow path switching valve and the second or third flow path switching valve. After the column is cleaned, the cleaning solution is discharged to a drain through the fourth flow path switching valve. Measurements are performed in the four columns sequentially, and measurement data are inputted into an arithmetic control device. Subsequently, data representing interactions between the sugar chain and the lectins are obtained.

Abstract: A two-dimensional liquid chromatograph includes a first-dimension separation channel for guiding a sample injected from a sample injection part to a first-dimension analysis column using a first-dimension analysis mobile phase for separation; two trap columns; an analysis channel for guiding components retained in the trap columns to a second-dimension analysis column using a second-dimension analysis mobile phase for analysis; and a channel switching mechanism. The switching mechanism connects the first-dimension separation channel to one of the trap columns and connecting the analysis channel to the other of the trap columns, and also switches connections between the trap columns and the channels.