Abstract: A display device includes a light-emitting element layer on the substrate and having a display area for displaying images, and a sealing layer covering the light-emitting element layer. The sealing layer includes a first inorganic film, an organic film on the first inorganic film, a second inorganic film on the organic film, and a third inorganic film. The first inorganic film and the second inorganic film are in contact with each other around the organic film. The third inorganic film, without overlapping with the display area, covers a peripheral portion of the organic film.

Abstract: The development of a new, targeted drug delivery paradigm coupled to improved PI3K inhibitors (e.g., PI3K? inhibitors) represents a significant advance in cancer therapy. Provided herein are compounds, such as compounds of Formula (I) and (II), and pharmaceutically acceptable salts, hydrates, solvates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof. The compounds provided herein are PI3K (e.g., PI3K?) inhibitors and are therefore useful for the treatment and/or prevention of various diseases (e.g., proliferative diseases such as cancer). Also provided herein are nanoparticles and nanogels (e.g., P-selectin targeting nanoparticles) comprising PI3K inhibitors, such a compound described herein. In certain embodiments, a nanoparticle or nanogel described herein encapsulates a compound described herein for targeting delivery to cancer cells or tumors.

Abstract: According to an embodiment, a structure is detachably attached to a bed apparatus. The bed apparatus includes a holder and a first frame that includes a portion extending in a first direction. The structure includes: a first portion of a columnar shape extending in a second direction that intersects the first direction; and a second portion continuous to the first portion and including a portion extending in a third direction that intersects the second direction. The first portion is inserted in the holder so that the holder holds the structure. When the structure is attached to the bed apparatus, an angle between the first direction and the third direction is variable. The structure that can facilitate aid of bed departure can be provided.

Abstract: A display device includes a light-emitting element layer on the substrate and having a display area for displaying images, and a sealing layer covering the light-emitting element layer. The sealing layer includes a first inorganic film, an organic film on the first inorganic film, a second inorganic film on the organic film, and a third inorganic film. The first inorganic film and the second inorganic film are in contact with each other around the organic film. The third inorganic film, without overlapping with the display area, covers a peripheral portion of the organic film.

Abstract: The present invention relates to compound (I) or a salt thereof which has a ROR?t inhibitory action. In the formula (I), each symbol is as defined in the specification.

Abstract: According to an embodiment, a bed apparatus includes a frame, a side rail, and a holder. The holder is secured to the frame. The holder holds the side rail to make the side rail switchable between a first position state where the side rail is in a first position and a second position state where the side rail is in a second position lower than the first position. The holder includes: a lock portion to lock the side rail in the first position state; a cover portion to cover at least part of the lock portion; a lever portion to be operated to release lock of the lock portion; and a stopper portion to make it difficult for the lever portion to operate to release the lock. The bed apparatus that can prevent erroneous release of the lock can be provided.

Abstract: A firewall device comprises a storage unit that stores therein one or more rules related to blocking a request for each of a plurality of WEB servers independently of the rule for another WEB server; a feature-amount calculating unit that calculates a feature amount for each of the WEB servers based on a number of detections with regard to each index in each of the WEB servers; and a rule updating unit that updates a rule stored in the storage unit for each of the WEB servers based on the feature amount calculated by the feature-amount calculating unit.

Abstract: The present invention relates to compound (I) or a salt thereof which has a ROR?t inhibitory action. In the formula (I), each symbol is as defined in the specification.

Abstract: An image blur correction device capable of reducing its size in a direction orthogonal to an optical axis. A holding frame holding an image capture device is held movable in an X-axis direction, a Y-axis direction, and a rotational direction about an axis extending in a Z-axis direction. A first guide member, a second guide member, and a third guide member guide the holding frame in the X-axis direction, Y direction-axis, and in the rotational direction, respectively. A first vibration actuator drives the first guide member, a second vibration actuator drives the second guide member, and a third vibration actuator drives the third guide member. The third vibration actuator is arranged at a location more remote from the rotation center of the third guide member than at least one of the first and second vibration actuators, as viewed from the Z-axis direction.

Abstract: A roll electrode is provided with a core, an electrode, a fixing part and a regulating part. The core extends in an axial direction and has a substantially circular outer circumference. The electrode has an expansion coefficient lower than that of the core. The electrode wound into a roll shape on the outer circumference of the core. The fixing part is fixed to an end portion from which the electrode starts being wound around the core. The regulating part regulates the axial movement of the electrode wound into the roll shape with respect to the core.

Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.

Abstract: A display device includes a display area configured by pixels including a light emitting area, and a frame area provided outside the display area. The display device includes a substrate, ribs formed separately in the display area and the frame area and arranged around the light emitting area in the display area and a mask support section that is disposed in the frame area and supports a film formation mask for forming a film at least above the ribs. A top portion of the mask support section is at least 10 ?m higher than a top portion of the ribs arranged in the display area in a thickness direction of the substrate.

Abstract: Provided is a heterocyclic amide compound that may have a PRS inhibitory action and is expected to be useful as a prophylactic or therapeutic agent for PRS associated diseases and the like including cancer. A compound represented by the following formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.

Abstract: Provided is a heterocyclic amide compound that may have a PRS inhibitory action and is expected to be useful as a prophylactic or therapeutic agent for PRS associated diseases and the like including cancer. A compound represented by the following formula (I): wherein a group represented by is a group represented by the following formula (II) or the following formula (III): and other symbols are as described in the DESCRIPTION, or a salt thereof.

Abstract: An image blur correction device capable of reducing its size in a direction orthogonal to an optical axis. A holding frame holding an image capture device is held movable in an X-axis direction, a Y-axis direction, and a rotational direction about an axis extending in a Z-axis direction. A first guide member, a second guide member, and a third guide member guide the holding frame in the X-axis direction, Y direction-axis, and in the rotational direction, respectively. A first vibration actuator drives the first guide member, a second vibration actuator drives the second guide member, and a third vibration actuator drives the third guide member. The third vibration actuator is arranged at a location more remote from the rotation center of the third guide member than at least one of the first and second vibration actuators, as viewed from the Z-axis direction.

Abstract: A solid electrolytic capacitor that comprises an anode that comprises a porous anode body and a dielectric layer is provided. The anode body is formed from a pressed and sintered valve metal powder having a specific charge of about 200,000 ?F*V/g or more and a phosphorous content of about 150 parts per million or less. A solid electrolyte overlies the anode.

Abstract: An apparatus tests specific processing performed by plural computing machine resources provided by one or plural computers. The apparatus adds an instruction request command to request an instruction from the apparatus at a predetermined position in a source code of the specific processing performed by each computing machine resource, and generates the source code with an additional command.

Abstract: An information processing system includes a management apparatus that includes a first processor configured to store first information on an access token indicating that a right to call an application programming interface exists and second information on the application programming interface in a memory, and execute an exchange for a different access token by using the first information and the second information stored in the memory; and a client apparatus that includes a second processor configured to provide the application programming interface or use the application programming interface by utilizing the exchange for the different access token by the management apparatus.

Abstract: A multicore fiber includes: a first core having a first propagation loss of a first light beam in a mode one order higher than a mode of a second light beam that transmits information. The first propagation loss is 0.02 dB/m or more and 1 dB/m or less, in a wavelength band of light beams including the second light beam that transmit the information when a bend having a diameter of 280 mm is applied to the multicore fiber.

Abstract: A multicore fiber for communication 10 which allows propagation of an optical signal includes: a clad 12; a core 11a which is arranged in a center of the clad 12; and seven to ten cores 11b which are arranged at equal intervals surrounding the core 11a, and the cladding diameter is 230 ?m, distances between centers of the mutually neighboring cores 11a and 11b are 30 ?m or more, distances between the centers of the cores 11b and an outer peripheral surface of the clad 12 are 35 ?m or more and a mode field diameter of light propagating in the cores 11a and 11b is 9 ?m to 13 ?m.