Abstract: Provided is a means for imparting hydrophilicity to a surface of a sanitary facility by means other than hydrophilic particles. A sanitary facility having a hydrophilized organic surface, wherein the hydrophilized organic surface has at least an organic cationic group, and a zeta potential at pH=7 of the hydrophilized organic surface is more than ?40 mV.

Abstract: The present invention addresses the problem of providing a lipid nanoparticle in which a nucleic acid, etc., required in genome editing is encapsulated and which can be produced by an alcohol dilution method using flow channels and contributes to high genome editing efficiency. The present invention pertains to a lipid nanoparticle which comprises a lipid component, a DNA nuclease, a guide RNA and a single-stranded oligonucleotide, wherein: the lipid component comprises a pH-sensitive cationic lipid, a neutral phospholipid and a polyalkylene glycol-modified lipid; the ratio of the pH-sensitive cationic lipid relative to the total lipids constituting the lipid nanoparticle is 30-50 mol %; the ratio of the neutral phospholipid relative to the total lipids constituting the lipid nanoparticle is 20-50 mol %; and the ratio of the polyalkylene glycol-modified lipid relative to the total lipids constituting the lipid nanoparticle is 1-4 mol %.

Abstract: The present invention provides lipid nanoparticles each containing a pH-sensitive cationic lipid represented by formula (I) [wherein a represents an integer of 3 to 5; b represents 0 or 1; R1 and R2 each independently represent a group represented by general formula (A) (wherein R11 and R12 each independently represent a linear or branched C1-15 alkyl group; c represents an integer of 1 to 7; and e represents an integer of 4 to 12); and X represents a group represented by general formula (B) (wherein d represents an integer of 0 to 3; and R3 and R4 each independently represent a C1-4 alkyl group or a C2-4 alkenyl group, in which R3 and R4 may be bonded to each other to form a 5- to 7-membered nonaromatic hetero ring) or a 5- to 7-membered nonaromatic hetero ring group]. (R1)(R2)C(OH)—(CH2)a-(O—CO)b-X (I) (R11)(R12)HC—(CH2)c-(CO—O)—(CH2)e-(A) —(CH2)d-N(R3)(R4) (B) [Chem.

Abstract: A display device is provided. The display device displays an image captured by a first camera of a plurality of cameras, the captured image representing a situation around a shovel, and when a predetermined object is detected within an imaging range of a second camera that is different from the first camera, the display device displays an image representing that the predetermined object is detected outside a range of the displayed captured image of the first camera.

Abstract: Provided is a dielectric thin film including a metal oxide. The metal oxide includes bismuth, sodium, barium, and titanium, at least a part of the metal oxide is a tetragonal crystal having a perovskite structure, and a (100) plane of at least a part of the tetragonal crystal is oriented in a normal direction of a surface of the dielectric thin film.

Abstract: Provided is a multilayer imaging device capable of both securing a wide sensitive region and securing an accumulated amount of charges. An imaging device according to an embodiment comprises a pixel, the pixel including a photoelectric conversion layer (15); a first electrode (11) positioned close to a first surface of the photoelectric conversion layer and electrically connected to the photoelectric conversion layer; a second electrode (16) positioned on a second surface opposite to the first surface of the photoelectric conversion layer; a charge accumulation electrode (12) disposed close to the first surface of the photoelectric conversion layer and spaced apart from the first electrode in a direction parallel to the first surface; and a third electrode (200) disposed at a position to have a portion overlapping a gap between the first electrode and the charge accumulation electrode in a direction perpendicular to the first surface.

Abstract: A first reading unit reads member identification information for uniquely identifying each of customers and a second reading unit reads commodity identification information of a commodity carried into the fitting area by the customer and commodity information of a commodity carried out of the fitting area. A collection and storage unit collects and stores, together with date-and-time information, membership information indicated by the member identification information when the customer enters the fitting area in association with commodity information indicated by the commodity identification information at the time of entering, and collects and stores, together with date-and-time information, membership information indicated by the member identification information when the customer exits the fitting area in association with commodity information indicated by the commodity identification information at the time of exiting.

Abstract: A system includes a distribution control server and a management server. The distribution control server controls data accumulation to make data related to a service that is provided to a user from a data accumulator a target for data distribution. The distribution control server controls data sharing for a data sharing destination to acquire the accumulated data. The distribution control server controls data providing for a data providing destination to acquire the accumulated data. The management server charges an accumulation platform usage fee related to the data accumulation to the data accumulator. The management server charges a sharing platform usage fee related to data sharing to the data sharing destination. The management server charges a providing platform usage fee related to data providing to the data providing destination.

Abstract: Provided are: a flow channel structure with which lipid particles or micelles, which are useful as nano-sized carriers, for example, in drug delivery systems, are produced with good control of particle size; and a method for forming lipid particles or micelles using the same. Said flow channel structure has a two-dimensional structure such as one in which multiple structural elements (baffles) of a specified width are alternately disposed from the two side faces in a micro-sized flow channel through which feedstock solutions are flowed.

Abstract: A nutrient intake amount estimation system according to an embodiment includes: a sensor that is disposed in a toilet space, and configured to detect an excretion smell related to excretion of a user of the toilet space; an estimation unit configured to estimate an estimated nutrient intake amount that is an amount of nutrients taken by the user by using an output of an estimation model that outputs information indicating an amount of nutrients estimated to be taken by the user in accordance with an input based on an output value of the sensor; and an output unit configured to output information based on the estimated nutrient intake amount.

Abstract: A sputtering target comprised of a plurality of members including a target material and a base material, wherein the plurality of members includes a first member and a second member laminated to each other, wherein the first member contains Al, and the second member contains Cu, wherein at least one of the first member and the second member contains Mg, wherein the sputtering target includes an alloy layer containing Al and Cu between the first member and the second member, the alloy layer being in contact with the first member and the second member, and wherein the alloy layer further includes an Mg-containing layer containing 5.0 at % or more of Mg in at least a part of the alloy layer.

Abstract: A piezoelectric thin film contains a metal oxide having a perovskite structure. The metal oxide contains bismuth, potassium, titanium, magnesium, iron, and an element M. The element M is at least one element selected from the group consisting of gallium and cobalt. At least a part of the metal oxide is at least one crystal selected from the group consisting of a tetragonal crystal and an orthorhombic crystal. A (001) plane of the crystal is oriented in a normal direction of a surface of the piezoelectric thin film.

Abstract: An evacuation guidance apparatus includes a server and one or a plurality of information terminals capable of moving in a commercial facility and capable of communicating with the server. The information terminal includes an emitting unit configured to emit specifying information for specifying a position of the information terminal including the emitting unit.

Abstract: The present invention provides a therapeutic agent for refractory viral infections, etc., which is capable of reducing or eliminating cccDNA from hepatocytes. The therapeutic agent for refractory viral infections according to the present invention is characterized by comprising a complex encapsulating poly-I or a poly-I analog and poly-C or a poly-C analog within a drug carrier useful for drug delivery into cells, wherein the surface of the carrier is conjugated with a molecule imparting the ability to accumulate in hepatocytes.

Abstract: The control unit includes a wiring board on which a connector is disposed. The connector is disposed on a back surface of the wiring board, the back surface being a back surface on a back side of a facing surface facing a body of the control unit. The wiring board includes legs protruding from the back surface on the back side of the facing surface facing the body.

Abstract: There is provided an imaging element includes a photoelectric conversion unit that includes a first electrode, a photoelectric conversion layer, and a second electrode, in which the photoelectric conversion unit further includes a charge storage electrode that has an opposite region opposite to the first electrode via an insulating layer, and a transfer control electrode that is opposite to the first electrode and the charge storage electrode via the insulating layer, and the photoelectric conversion layer is disposed above at least the charge storage electrode via the insulating layer.

Abstract: There is provided a Cu—Al binary alloy sputtering target with a high Al content while suppressing occurrence of cracks on the sputtering target, and a method for manufacturing the same. A sputtering target is composed of a sintered body containing a binary alloy of Cu and Al, the rest being inevitable impurities, wherein a content (at %) of Cu and Al satisfies a relational expression of 0.48?Al/(Cu+Al)?0.70, and wherein a relative density is 95% or more.

Abstract: A solid-state imaging device, an electronic device, and a distance measurement system for miniaturization of pixels in a device that outputs a luminance signal and an event signal. A device includes: a pixel array unit in which an event pixel that detects that a luminance change exceeds a predetermined threshold and a gradation pixel that outputs a luminance signal of a gradation level according to a light amount of incident light are mixed, in which a color filter of the same color is formed in units of two or more pixels in the gradation pixel, and the event pixel is disposed with a region size in which at least two of the gradation pixels are arranged in a row direction or a column direction. The present disclosure can be applied to, for example, a distance measurement system or the like that generates image information and distance measurement information.

Abstract: An information transaction device is connected to an information holding device including a storage unit storing personal information and includes a sharing approval reception unit configured to receive approval of sharing of the personal information by an information sharing destination device from a user associated with the personal information, a provision approval reception unit configured to receive approval of provision which is transmission of the personal information to an information provision destination device, from the user associated with the personal information, a sharing instruction unit configured to, in a case where the sharing approval reception unit receives the approval of the sharing, instruct the information holding device to perform the sharing, and a provision instruction unit configured to, in a case where the provision approval reception unit receives the approval of the provision, instruct the information holding device to perform the provision.

Abstract: A wafer grinding method includes a first grinding step of grinding a first wafer for testing held on a chuck table to a finishing thickness, a thickness measuring step of measuring, at a plurality of locations in a radial direction, a thickness of the first wafer ground in the first grinding step, a nozzle positioning step of positioning a jetting nozzle directly above a portion of the first wafer having a thickness that is one of the thicknesses of the first wafer measured at the plurality of locations in the thickness measuring step and that is either greater or smaller than a reference thickness set beforehand, and a second grinding step of grinding a second wafer that is next held on the chuck table, while jetting cold water or warm water from the jetting nozzle to the second wafer.