Abstract: A method enables olefin compound production with a high productivity, and an enzyme is used in the method. Mutations involving amino acid substitution are introduced into various sites of diphosphomevalonate decarboxylase (MVD) to prepare multiple MVD variants. Then, these variants are evaluated in terms of catalytic activity for producing an olefin compound such as isoprene, and have found as a result that the catalytic activity is improved when serine at position 153 and threonine at position 209 are each substituted with a different amino acid. In addition, the catalytic activity of the variants is further improved when glycine at position 152 is further substituted with a different amino acid.

Abstract: Mutations involving amino acid substitution were introduced into various sites of diphosphomevalonate decarboxylase (MVD), thus preparing a large number of MVD variants. Then, the variants were each evaluated in terms of a catalytic activity for production of olefin compounds such as isoprene. As a result, it was found that substitution of glycine at position with a different amino acid resulted in improvement in the catalytic activity. In addition, it was found that the MVD in which arginine at position and threonine at position in addition to the position were further substituted with different amino acids, respectively, also had the high catalytic activity.

Abstract: A method which enables olefin compound production with a high productivity and an enzyme used in the method, a mutation involving amino acid substitution has been introduced into various sites of diphosphomevalonate decarboxylase (MVD), thus preparing a large number of MVD variants. Next, the result of evaluating the variants for the catalytic activity related to the production of olefin compounds such as isoprene has revealed that MVD whose threonine at position 209 is substituted with a different amino acid has the catalytic activity, and that MVD whose arginine at position 74 is further substituted with a different amino acid in addition to position 209 has the catalytic activity at higher levels.

Abstract: The present technology provides a rubber composition for sidewalls containing, a diene rubber, from 10 to 120 parts by mass of a carbon black, and from 3 to 30 parts by mass of an acid-modified polyolefin having a melting point of from 100 to 150° C. per 100 parts by mass of the diene rubber, a main chain of the acid-modified polyolefin being a homopolymer of an olefin; and a pneumatic tire using the same in sidewalls thereof.

Abstract: A rubber composition includes a diene rubber (A), a silica (B), a silane coupling agent (C), and an acid-modified polyolefin (D); the diene rubber (A) containing not less than 30 mass % of an aromatic vinyl-conjugated diene copolymer rubber; the acid-modified polyolefin (D) having at least one type of repeating unit selected from the group consisting of propylene, 1-butene, and 1-octene; a content of the silica (B) being from 5 to 150 parts by mass per 100 parts by mass of the diene rubber (A); and a total content of the silane coupling agent (C) and the acid-modified polyolefin being from 5 to 30 parts by mass per 100 parts by mass of the diene rubber (A). Such rubber composition is capable of achieving both excellent vulcanization properties and low heat build-up. A pneumatic tire includes such rubber composition.

Abstract: A medical image display device having a touch panel that displays a medical image, includes: a hardware processor that accepts an operation on the touch panel and detects a drag operation on a mark corresponding to a function selected from a plurality of functions; calculates a movement position of the mark according to a rule corresponding to at least one of the selected function, an object, and a user based on coordinates of a touch position in the drag operation; and causes the touch panel to display the medical image and the mark and to move the mark on the medical image based on the calculated movement position, wherein the hardware processor calculates the movement position of the mark such that a movement trajectory of the touch position and a movement trajectory of the mark are different from each other.

Abstract: The present invention is to provide a polymer which has a C—P bond. The present invention can provide a phosphoric acid-modified polymer having a double bond, and a phosphorus substituent containing a phosphorus atom that directly bonds to a carbon atom.

Abstract: In a semiconductor device according to related art, it is impossible to sufficiently correct an input offset of an operational amplifier.

Abstract: A rubber composition includes a sulfur-crosslinkable diene rubber, from 1 to 100 parts by mass of carbon black and/or from 5 to 150 parts by mass of an inorganic filler, from 0.5 to 30 parts by mass of a sulfur-containing compounding agent, and from 0.01 to 20 parts by mass of a phosphine borane compound based on 100 parts by mass of the sulfur-crosslinkable diene rubber. The rubber composition may be applied in at least one type selected from the group consisting of a capped tread, a side wall, a belt, an inner liner, a carcass, and a bead of a pneumatic tire.

Abstract: The present technology provides a rubber composition for sidewalls containing, a diene rubber, from 10 to 120 parts by mass of a carbon black, and from 3 to 30 parts by mass of an acid-modified polyolefin having a melting point of from 100 to 150° C. per 100 parts by mass of the diene rubber, a main chain of the acid-modified polyolefin being a homopolymer of an olefin; and a pneumatic tire using the same in sidewalls thereof.

Abstract: The present technology provides a rubber composition including: a diene rubber; at least one type selected from the group consisting of carbon black and a white filler; an acid-modified polyolefin; and a polyamide polyether elastomer. The content of the at least one type selected from the group consisting of carbon black and a white filler is from 1 to 100 parts by mass per 100 parts by mass of the diene rubber. The total content of the acid-modified polyolefin and the polyamide polyether elastomer is from 3 to 35 parts by mass per 100 parts by mass of the diene rubber. The present technology also provides a pneumatic tire which uses the rubber composition.

Abstract: Provided are a rubber composition containing from 1 to 30 parts by mass of an acid-modified polyolefin and from 0.3 to 20 parts by mass of at least one type selected from the group consisting of terpene resins and petroleum resins per 100 parts by mass of a diene rubber; and a pneumatic tire using the same.

Abstract: The present technology provides a rubber composition comprising: a diene rubber, an acid-modified polyolefin (A), and a polyolefin (B). The mass ratio of the acid-modified polyolefin (A) to the polyolefin (B) is from 1:5 to 5:1. The total amount of the acid-modified polyolefin (A) and the polyolefin (B) is from 3 to 60 parts by mass per 100 parts by mass of the diene rubber. The present technology also provides a pneumatic tire that uses the rubber composition.

Abstract: The present technology provides a rubber composition wherein from 1 to 100 parts by mass of carbon black and/or from 10 to 150 parts by mass of inorganic filler, from 1 to 30 parts by mass of sulfur-containing compounding agent, and from 0.1 to 20 parts by mass of tin oxide compound, are blended per 100 parts by mass of sulfur-crosslinkable diene rubber; and a pneumatic tire that uses this rubber composition in a cap tread.

Abstract: The present technology provides a rubber composition comprising 100 parts by mass of (A) diene rubber, from 10 to 120 parts by mass of (B) carbon black, from 1 to 50 parts by mass of a (C) polyamide elastomer, and from 0.01 to 1.2 parts by mass of a (D) sulfenamide-based vulcanization retarder.

Abstract: A polyamide elastomer-containing rubber composition according to the present technology comprises, 100 parts by mass of (A) a diene rubber, from 30 to 80 parts by mass of (B) carbon black having a nitrogen adsorption specific surface area (N2SA) of at least 35 m2/g and from 1 to 30 parts by mass of (C) a polyamide elastomer, the mass ratio of the (B) carbon black to the (C) polyamide elastomer being 1:0.35 to 1:1.

Abstract: Provided is a rubber composition having an intramolecular double bond capable of sulfur cross-linking, comprising at least one of 1 to 100 parts by mass of carbon black and 10 to 150 parts by mass of an inorganic filler other than carbon black, 0.1 to 50 parts by mass of a sulfur-containing compounding agent and 0.1 to 30 parts by mass of a hydrocarbon compound with both terminal groups thioesterified, per 100 parts by mass of the rubber having an intramolecular double bond capable of sulfur cross-linking. This rubber composition can provide a vulcanized substance having excellent toughness, for example, as a part of at least one of a cap tread, a side wall, a belt, an inner liner, a carcass and a bead of a pneumatic tire without substantially reducing processability of an unvulcanized substance and vulcanizate physical properties of the vulcanized substance.

Abstract: Provided is a rubber composition having an intramolecular double bond capable of sulfur cross-linking, comprising at least one of 1 to 100 parts by mass of carbon black and 10 to 150 parts by mass of an inorganic filler other than carbon black, 0.1 to 50 parts by mass of a sulfur-containing compounding agent and 0.1 to 30 parts by mass of a hydrocarbon compound with both terminal groups thioesterified, per 100 parts by mass of the rubber having an intramolecular double bond capable of sulfur cross-linking. This rubber composition can provide a vulcanized substance having excellent toughness, for example, as a part of at least one of a cap tread, a side wall, a belt, an inner liner, a carcass and a bead of a pneumatic tire without substantially reducing processability of an unvulcanized substance and vulcanizate physical properties of the vulcanized substance.

Abstract: The present technology provides a rubber composition wherein from 1 to 100 parts by mass of carbon black and/or from 10 to 150 parts by mass of inorganic filler, from 1 to 30 parts by mass of sulfur-containing compounding agent, and from 0.1 to 20 parts by mass of tin oxide compound, are blended per 100 parts by mass of sulfur-crosslinkable diene rubber; and a pneumatic tire that uses this rubber composition in a cap tread.

Abstract: Provided is a terminal borinic acid group-modified polymer having a borinic acid group at least at a molecular terminus thereof, comprising a polymer of at least one of a styrene monomer and a diene monomer. The above terminal borinic acid group-modified polymer may be manufactured by performing a polymerization reaction of at least one of a styrene monomer and a diene monomer in the presence of an anionic polymerization initiator, and then adding a cyclic boronic anhydride to quench the polymerization reaction. When the resulting terminal borinic acid group-modified polymer is added to a silica-containing rubber composition for automobile pneumatic tires as a component thereof, the dispersibility of silica compounded therein can be improved, fully achieving a performance of a good balance between reduced rolling resistance inherent in silica and stability on a wet road.