Patents by Inventor Yusuke TATENO

Yusuke TATENO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AMIDE DERIVATIVE HAVING ANTIVIRAL ACTIVITY
    Publication number: 20230382893
    Abstract: The present invention provides a compound represented by formula (I): wherein the dashed line indicates the presence or absence of a bond; R1 is carboxy or the like; L is substituted or unsubstituted non-aromatic carbocyclyldiyl or the like; R2 is substituted or unsubstituted alkyl; R3 is a hydrogen atom or the like; X is ?CRX— or ?N—; Y is ?CRY— or ?N—; U is —CRU? or —N?; V is —CRV? or —N?; W is ?CRW— or ?N—; ZA is —C? or —N—; ZB is —CR5R6— or the like; ZC is —CR7R8— or the like; RX, RY, RV and RW are each independently a hydrogen atom or the like; RU is a hydrogen atom or the like; R5 and R6 are each independently a hydrogen atom or the like; R7 and R8 are each independently a hydrogen atom or the like; R4 is substituted or unsubstituted alkyloxy or the like, or a pharmaceutically acceptable salt thereof, having an antiviral activity; and a pharmaceutical composition comprising the same.
    Type: Application
    Filed: October 27, 2021
    Publication date: November 30, 2023
    Applicants: Shionogi & Co., Ltd., UBE Corporation
    Inventors: Azusa OKANO, Yusuke TATENO, Kouhei NODU, Shinji SUZUKI, Toshiyuki AKIYAMA, Masaaki MATOYAMA, Hirota AKAZA, Takashi FUKUDA
  • DIHYDROPYRAZOLOPYRAZINONE DERIVATIVE HAVING MGAT2 INHIBITORY ACTIVITY
    Publication number: 20220135577
    Abstract: The present invention provides a compound represented by a following formula. A compound represented by, wherein R1 is hydrogen, hydroxy, or the like; R2a and R2b may be taken together with an adjacent carbon atom to form ring B, ring B is a substituted or unsubstituted non-aromatic carbocycle or a substituted or unsubstituted non-aromatic heterocycle; R3a is hydrogen, halogen, hydroxy, or the like; R3b is hydrogen, halogen, hydroxy, or the like; R4a is a group represented by formula: L3 is a single bond or substituted or unsubstituted alkylene, R7 is hydrogen, halogen, hydroxy, or the like, and R4b is halogen, cyano, carboxy, or the like, or its pharmaceutically acceptable salt.
    Type: Application
    Filed: January 10, 2020
    Publication date: May 5, 2022
    Applicant: Shionogi & Co., Ltd.
    Inventors: Yusuke TATENO, Manabu KATOU, Toshihiro WADA
  • FUSED RING DERIVATIVE HAVING MGAT-2 INHIBITORY ACTIVITY
    Publication number: 20220073518
    Abstract: The present invention provides the compound represented by the following formula (I): wherein a moiety represented by formula: or the like. The symbols are defined in the specification. The compounds of the present invention have MGAT2 inhibitory activity, and are useful as a medicine for treatment of MGAT2-associated diseases including obesity, metabolic syndrome, hyperlipidemia, hypertriglyceridemia, hyper-VLDL-triglyceridemia, hyperfattyacidemia, diabetes mellitus, and arteriosclerosis.
    Type: Application
    Filed: November 12, 2021
    Publication date: March 10, 2022
    Applicant: Shionogi & Co., Ltd.
    Inventors: Kouhei NODU, Yusuke TATENO, Kengo MASUDA, Yuji NISHIURA, Yoshikazu SASAKI, Yu HINATA
  • Fused ring derivative having MGAT-2 inhibitory activity
    Patent number: 11198695
    Abstract: The present invention provides the compound represented by the following formula (I): wherein a moiety represented by formula: or the like. The symbols are defined in the specification. The compounds of the present invention have MGAT2 inhibitory activity, and are useful as a medicine for treatment of MGAT2-associated diseases including obesity, metabolic syndrome, hyperlipidemia, hypertriglyceridemia, hyper-VLDL-triglyceridemia, hyperfattyacidemia, diabetes mellitus, and arteriosclerosis.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: December 14, 2021
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Kouhei Nodu, Yusuke Tateno, Kengo Masuda, Yuji Nishiura, Yoshikazu Sasaki
  • FUSED RING DERIVATIVE HAVING MGAT-2 INHIBITORY ACTIVITY
    Publication number: 20200291025
    Abstract: The present invention provides the compound represented by the following formula (I): wherein a moiety represented by formula: or the like. The symbols are defined in the specification. The compounds of the present invention have MGAT2 inhibitory activity, and are useful as a medicine for treatment of MGAT2-associated diseases including obesity, metabolic syndrome, hyperlipidemia, hypertriglyceridemia, hyper-VLDL-triglyceridemia, hyperfattyacidemia, diabetes mellitus, and arteriosclerosis.
    Type: Application
    Filed: July 13, 2018
    Publication date: September 17, 2020
    Applicant: Shionogi & Co., Ltd.
    Inventors: Kouhei NODU, Yusuke TATENO, Kengo MASUDA, Yuji NISHIURA, Yoshikazu SASAKI, Yu HINATA
  • Fused pyrazole derivative having autotaxin inhibitory activity
    Patent number: 10189843
    Abstract: The present invention provides a compound of formula (1), wherein R1, R2, R3, R4a, R4b, R5a and R5b are as defined in the description, which has an autotaxin inhibitory activity, a pharmaceutical composition comprising the compound as an active ingredient, and a method of prevention or treatment of a disease involving autotaxin, which is characterized by administering the compound.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: January 29, 2019
    Assignees: THE UNIVERSITY OF TOKYO, TOHOKU UNIVERSITY, SHIONOGI & CO., LTD.
    Inventors: Tetsuo Nagano, Takayoshi Okabe, Hirotatsu Kojima, Mitsuyasu Kawaguchi, Osamu Nureki, Ryuichiro Ishitani, Hiroshi Nishimasu, Junken Aoki, Chiaki Fujikoshi, Manabu Katou, Masahide Odan, Nobuyuki Tanaka, Yusuke Tateno, Junji Yamane
  • Pyrimidinone derivative having autotaxin-inhibitory activity
    Patent number: 10183949
    Abstract: A compound according to any one of formula (Ia) to (Ic), or its pharmaceutically acceptable salt: wherein R1, R2, R3, R4a, R4c, R5 are as defined in the description.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: January 22, 2019
    Assignees: THE UNIVERSITY OF TOKYO, TOHOKU UNIVERSITY, SHIONOGI & CO., LTD.
    Inventors: Tetsuo Nagano, Takayoshi Okabe, Hirotatsu Kojima, Mitsuyasu Kawaguchi, Osamu Nureki, Ryuichiro Ishitani, Hiroshi Nishimasu, Junken Aoki, Nobuyuki Tanaka, Yasuhiko Kanda, Yoshiyuki Kioi, Yusuke Tateno, Shiro Kida, Junji Yamane
  • PYRIMIDINONE DERIVATIVE HAVING AUTOTAXIN-INHIBITORY ACTIVITY
    Publication number: 20170158704
    Abstract: A compound according to any one of formula (Ia) to (Ic), or its pharmaceutically acceptable salt: wherein R1, R2, R3, R4a, R4c, R5 are as defined in the description.
    Type: Application
    Filed: February 24, 2017
    Publication date: June 8, 2017
    Applicants: The University of Tokyo, TOHOKU UNIVERSITY, Shionogi & Co., Ltd.
    Inventors: Tetsuo NAGANO, Takayoshi OKABE, Hirotatsu KOJIMA, Mitsuyasu KAWAGUCHI, Osamu NUREKI, Ryuichiro ISHITANI, Hiroshi NISHIMASU, Junken AOKI, Nobuyuki TANAKA, Yasuhiko KANDA, Yoshiyuki KIOI, Yusuke TATENO, Shiro KIDA, Junji YAMANE
  • FUSED PYRAZOLE DERIVATIVE HAVING AUTOTAXIN INHIBITORY ACTIVITY
    Publication number: 20160376278
    Abstract: The present invention provides a compound of formula (1), wherein R1, R2, R3, R4a, R4b, R5a and R5b are as defined in the description, which has an autotaxin inhibitory activity, a pharmaceutical composition comprising the compound as an active ingredient, and a method of prevention or treatment of a disease involving autotaxin, which is characterized by administering the compound.
    Type: Application
    Filed: February 26, 2015
    Publication date: December 29, 2016
    Applicants: The University of Tokyo, TOHOKU UNIVERSITY, Shionogi & Co., Ltd.
    Inventors: Tetsuo NAGANO, Takayoshi OKABE, Hirotatsu KOJIMA, Mitsuyasu KAWAGUCHI, Osamu NUREKI, Ryuichiro ISHITANI, Hiroshi NISHIMASU, Junken AOKI, Chiaki FUJIKOSHI, Manabu KATOU, Masahide ODAN, Nobuyuki TANAKA, Yusuke TATENO, Junji YAMANE
  • 8-SUBSTITUTED IMIDAZOPYRIMIDINONE DERIVATIVE HAVING AUTOTAXIN INHIBITORY ACTIVITY
    Publication number: 20160002247
    Abstract: A compound of formula (I) wherein variables are as defined herein having an autotaxin inhibitory effect and a pharmaceutical composition comprising the same.
    Type: Application
    Filed: February 27, 2014
    Publication date: January 7, 2016
    Applicants: THE UNIVERSITY OF TOKYO, TOHOKU UNIVERSITY, Shionogi & Co., Ltd.
    Inventors: Tetsuo NAGANO, Takayoshi OKABE, Hirotatsu KOJIMA, Mitsuyasu KAWAGUCHI, Osamu NUREKI, Ryuichiro ISHITANI, Hiroshi NISHIMASU, Junken AOKI, Nobuyuki TANAKA, Chiaki FUJIKOSHI, Yusuke TATENO, Toshihiro WADA