Yusuke Yokota has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
Abstract: The object of the present invention is to provide a nucleic acid agent that can be efficiently delivered to the nervous system, particularly the central nervous system to which the BBB mechanism prevents drug delivery, and can produce an antisense effect on a target transcriptional product at the delivered site, and a composition comprising the same. Provided is a double-stranded nucleic acid complex formed by annealing a first nucleic acid strand capable of hybridizing to part of a target transcriptional product, and has an antisense effect on the target transcriptional product, to a second nucleic acid strand comprising a base sequence complementary to the first nucleic acid strand, and is bound to tocopherol or an analog thereof, cholesterol or an analog thereof, or a substituted or unsubstituted C1-30 alkyl group, a substituted or unsubstituted C2-30 alkenyl group, or a substituted or unsubstituted C1-30 alkoxy group.
March 22, 2019
June 3, 2021
NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY
Abstract: Provided is a system that enables training for catheter surgery without using radiation. The system offering training for catheter surgery includes: a light source; a blood vessel model to which a catheter having a fluorescent agent applied thereto is inserted; a tank in which the blood vessel model is placed; a filter for rejecting white light that is not transmitted through the blood vessel model, of illuminating light from the light source; a camera for imaging fluorescence transmitted through the filter; a driver for changing the attitude of the light source; and a computer that performs a process of reversing black and white of an image signal output from the camera.
Abstract: A multilayer ceramic electronic component includes a laminate including dielectric ceramic layers and at least a pair of internal electrode layers laminated together, the laminate including a pair of main surfaces that oppose each other in a lamination direction, a pair of side surfaces that oppose each other in a width direction perpendicular or substantially perpendicular to the lamination direction, and a pair of end surfaces that oppose each other in a length direction perpendicular or substantially perpendicular to the lamination direction and the width direction, a pair of side surface layers respectively provided on the side surfaces of the laminate, a pair of main surface layers covering interfaces between the laminate and the side surface layers respectively provided on the main surfaces of the laminate, and a pair of external electrodes respectively connected to the internal electrode layers respectively provided on the end surfaces of the laminate.
Abstract: An antenna device includes an antenna housing and an antenna element. The antenna element is accommodated in the antenna housing and receives signals in a first frequency band and a second frequency band which is lower than the first frequency band. The antenna element includes a first element that receives signals in the first frequency band and a second element that surrounds the first element and receives signals in the second frequency band. The first element includes a conductive plate which has a predetermined area, the second element includes a conductive plate which has a predetermined area, and the conductive plates are provided in an identical plane or a substantially identical plane.
Abstract: A multilayer ceramic electronic component includes a multilayer body including two major surfaces opposite to each other in a layer stacking direction, two side surfaces opposite to each other in a widthwise direction orthogonal or substantially orthogonal to the layer stacking direction, and two end surfaces opposite to each other in a lengthwise direction orthogonal or substantially orthogonal to the layer stacking direction and the widthwise direction, and external electrodes provided on the two end surfaces. A method for manufacturing the multilayer ceramic capacitor component includes preparing a plurality of multilayer bodies, stacking the plurality of multilayer bodies via a binder, rotating the plurality of multilayer bodies by about 90° with the lengthwise direction defining and functioning as an axis of rotation, and providing a side gap portion; and removing the binder from the multilayer body provided with the side gap portion.
Abstract: An antenna device for vehicle that is attached to a roof of a vehicle, the antenna device for vehicle including: an antenna base; an antenna case covering the antenna base from above; and an antenna element provided inside the antenna case, wherein the antenna base has a metal base fixed to the roof, and a metal plate electrically connected to the metal base.
Abstract: A driving handover control device includes a memory and a processor coupled to the memory. In a case in which driving is handed over from a first state in which a vehicle is traveling by remote driving by a first driver from outside the vehicle or by occupant driving by the first driver in the vehicle, to a second state in which the vehicle travels by the remote driving or the occupant driving by a second driver who is different from the first driver, the processor is configured to cause transition from the first state to a third state in which the vehicle is caused to travel by automatic driving, and then cause transition from the third state to the second state.
Abstract: A vehicle controller device includes a first processor. The first processor is configured to acquire biometric information of an occupant, in cases in which the compromised state is determined to have arisen, to communicate check-up information to check the well-being of the occupant using a report device provided inside the vehicle, to receive a response from the occupant whose well-being is being checked, to notify switchover information to an operation device in order to switch the vehicle from manual driving to remote driving in which the vehicle travels based on operation information in cases in which the response has not been received, and to perform the remote driving in cases in which the switchover information has been received by the operation device and operation-ready information indicating that the remote driving is possible has subsequently been received from the operation device.
Abstract: vehicle controller device including: a communication section that is configured to communicate with an operation device external to a vehicle and with another vehicle; a processor being configured to: acquire peripheral information regarding a periphery of the vehicle; generate a travel plan for the vehicle based on the peripheral information of the vehicle; hand over operation authority to the operation device in a case in which a priority vehicle capable of taking priority over the vehicle when traveling on a road approaches the vehicle; acquire remote operation information to operate the vehicle, from the operation device to which operation authority has been handed over; control autonomous driving in which the vehicle travels based on the generated travel plan and also control remote driving in which the vehicle travels based on the acquired remote operation information; and output other-vehicle operation information to operate the other vehicle during remote driving.
Abstract: A vehicle controller device is provided including a travel control section configured to control autonomous driving and remote driving, a biometric information acquisition section configured to acquire biometric information of an occupant, a state determination section configured to determine, based on the biometric information acquired by the biometric information acquisition section, whether or not an abnormality predicted state has arisen in which manual driving by operation by the occupant is predicted to become compromised and also whether or not an abnormal state has arisen in which manual driving is compromised, a notification section configured to notify an operation device of a determined state in cases in which either the abnormality predicted state or the abnormal state is determined to have arisen, and a reception section capable of receiving operation-ready information indicating that operation by a remote operator is possible from the operation device in response to the notification.
Abstract: An operation device including: an operation section configured to receive operation by a remote operator conferred with operation authority to operate a vehicle capable of autonomous driving; a communication section configured to transmit, to the vehicle, operation information for remote driving based on the operation received by the operation section; a memory; and a processor coupled to the memory, the processor being configured to: acquire biometric information regarding the remote operator, determine whether or not a compromised state, in which operation of the vehicle by the remote operator is compromised, has arisen based on the acquired biometric information, and transfer operation authority of the vehicle to another remote operator in a case in which the compromised state has been determined to have arisen.
Abstract: A vehicle controller device includes a processor. The processor is configured to control autonomous driving in which the vehicle travels based on a travel plan, and to control remote driving in which the vehicle travels based on operation information received by a communication section. The processor is further configured to output information relating to a driving state corresponding to manual driving by operation by an occupant of the vehicle, autonomous driving, or remote driving, and information relating to a transitional state corresponding to a transition from one driving state to another driving state, to a notification unit configured to perform notification of the driving state and the transitional state.
Abstract: A vehicle controller device including: a communication section configured to perform communication between an operation device external to a vehicle and another vehicle; a memory; and a processor that is coupled to the memory, the processor being configured to: acquire peripheral information regarding a periphery of the vehicle from a peripheral information detection section, generate a travel plan for the vehicle based on the peripheral information of the vehicle, acquire operation information to operate the vehicle from the operation device, control autonomous driving in which the vehicle travels based on the generated travel plan and also control remote driving in which the vehicle travels based on the acquired operation information, acquire peripheral information from the other vehicle in a case in which the processor is unable to acquire peripheral information, and hand over operation authority to the operation device when peripheral information is being acquired by the processor.
Abstract: A vehicle controller device including: a communication section configured to receive operation information to operate a vehicle from an operation device located externally to the vehicle; a first memory; and a first processor, the first processor being configured to: acquire peripheral information regarding a periphery of the vehicle from a peripheral information detection section; generate a travel plan for the vehicle based on the peripheral information of the vehicle; control autonomous driving in which the vehicle travels based on the generated travel plan and also control remote driving in which the vehicle travels based on the received operation information; predict that a compromised state in which autonomous driving of the vehicle becomes compromised will arise based on environmental information including meteorological information received by the communication section; and notify the operation device of the compromised state in a case in which the compromised state has been predicted to arise.
Abstract: An inspection jig may include: an electrode; a probe, the probe having a rear end portion and a tip portion to contact a bump; and a support member supporting the probe. The probe may include: an outer tubular body that is electrically conductive; and an inner tubular body that is electrically conductive, the inner tubular body being inserted into the outer tubular body. The outer tubular body may include outer spring parts to bias the rear end portion. The inner tubular body may include inner spring parts. The tip portion may be a first end of the inner tubular body, and protrudes from a first end of the outer tubular body. The support member may hold the outer tubular body such that the rear end portion is brought into contact with the electrode by the biasing force of the outer spring parts.
Abstract: The present invention relates to a device maintainer, a device maintenance system, a device maintenance method, a device maintenance program, and a recording medium, which are capable of supporting an accurate operation and improving an operation efficiency in the maintenance operation of the device or a recording operation of the maintenance result. A device maintainer having a maintenance information display for displaying maintenance information regarding a maintenance of a device; a list display for displaying a maintenance list listing a maintenance item for the device to be a maintenance target together with the displayed maintenance information and enabling designation of the maintenance item; and a maintainer for performing the maintenance based on the designated maintenance item for the device to be the maintenance target.
Abstract: A calibration work support device includes a calibration target setter configured to set a target value of a simulation signal that is input to a device in calibration of the device and an input order of the target value in the calibration, a simulation signal acquirer configured to acquire an input value based on the simulation signal input to the device, a graph generator configured to generate a graph indicating a transition of the target value set by the calibration target setter and the input value acquired by the simulation signal acquirer, and a data output unit configured to output the graph generated by the graph generator.
Abstract: A data generating apparatus according to the one aspect of the present invention may include a converter configured to acquire conversion information in which a conversion rule is defined for converting first data acquired by performing a maintenance operation into second data processable by a facility maintenance management system and to convert the first data in accordance with the conversion rule defined in the acquired conversion information to generate the second data.
Abstract: A vehicular antenna device capable of preventing reception trouble in a radio, a TV receiver, or the like due to noise by suppressing electromagnetic noise radiated from an electronic device or the like is provided. A vehicular antenna device is equipped with an antenna base 2 which is fixed to a vehicle body via an attaching member, an antenna case which covers the antenna base, and an antenna element 5 and a camera module 10 as an electronic device which are disposed in an internal space surrounded by the antenna base 2 and the antenna case. A camera module case 40 surrounds a circuit board 50 of the camera module 10 and thereby shields it.