Abstract: Provided is an isolation and purification method for isolating and purifying extracellular vesicles. In the method for isolating and purifying extracellular vesicles from a solution containing the extracellular vesicles and unnecessary substances. The isolation and purification method is an adsorbent treatment method in which a solution containing the extracellular vesicles and unnecessary substances is brought into contact with an adsorbent to cause the adsorbent to adsorb and retain the unnecessary substances other than the extracellular vesicles. The adsorbent is a porous granular material having a pore, an interior of the pore being positively charged, and the adsorbent can adsorb and retain, in the interior of the pore, negatively charged unnecessary substances other than the extracellular vesicles.

Abstract: A determination method is provided, which determines a charging reception performance and/or a discharging performance of an energy storage apparatus. The method includes: acquiring an open circuit voltage of the energy storage apparatus after electricity is supplied with an assumed electricity supply pattern based on a charging state of the energy storage apparatus at a point of time of determination; acquiring a change in voltage attributed to the assumed electricity supply pattern after electricity is supplied with the assumed electricity supply pattern based on an internal resistance, a charging state and a temperature at the point of time of determination; acquiring a change in voltage attributed to electricity supply history before the electricity is supplied with the assumed electricity supply pattern based on a polarization component before the electricity is supplied with the assumed electricity supply pattern.

Abstract: [Object] To provide an isolation and purification method for isolating and purifying extracellular vesicles. [Solution] An isolation and purification method of extracellular vesicles is disclosed. A hollow fiber membrane has an inner diameter of 0.2 mm to 1.4 mm and a molecular weight cut-off of 100000 to 1000000. Filtering includes a first filtration process of press-fitting the culture supernatant of the mesenchymal stem cells from a first opening on one end side of the hollow fiber membrane and filtering the culture supernatant to separate the culture supernatant into a permeate and a first concentrate, and a second filtration process of press-fitting the first concentrate from a second opening on the other end side of the hollow fiber membrane and filtering the first concentrate to separate the first concentrate into a permeate and a second concentrate.

Abstract: A method of examining a possibility of a subject having pancreatic cancer, including measuring GPRC5C (G protein-coupled receptor family C group 5 member C) present in an exosome in a specimen collected from the subject.

Abstract: A service providing system, a service providing method, and a program stored in a non-transitory recording medium, each controls execution of a workflow defining a plurality of processes; in response to an occurrence of an authentication error in a predetermined process authenticated by an authentication server among the plurality of processes of the workflow, controlling updating of authentication information corresponding to the predetermined process, while suspending the execution of the workflow; and resumes the execution of the workflow based on completion of the updating of the authentication information.

Abstract: A service providing system includes a device; and an information processing system. The information processing system stores each user of the information processing system and each user of an external service system in association with each other. The device accepts a specification of a first application and a user of the information processing system; acquires data for which a user of the external service system, associated with the user of the information processing system, has an authority, among data relating to the first application included in the external service system; displays a screen to accept a selection of one piece of data from the acquired data; accepts the one piece of data for which the selection is accepted via the screen; and requests the external service system to store information acquired by the device in association with the accepted one piece of data.

Abstract: An information processing system including an information processing apparatus and a service providing system mutually communicating through a network, wherein the information processing apparatus includes a display process unit to cause a screen of a display device to display a process flow that defines an execution order of processes executed by the service providing system, and a setup reception unit to receive a setup, in which predetermined processes related to first and second external services are associated, and the display process unit displays the processes to be executed in the execution order, and an issue that the setup reception unit has received the predetermined processes related to the first and second external services in association with each other, the service providing system includes a process flow execution unit to execute the processes included in the process flow transmitted from the information processing apparatus in the defined execution order.

Abstract: A service providing system includes a device; and an information processing system. The information processing system stores each user of the information processing system and each user of an external service system in association with each other. The device accepts a specification of a first application and a user of the information processing system; acquires data for which a user of the external service system, associated with the user of the information processing system, has an authority, among data relating to the first application included in the external service system; displays a screen to accept a selection of one piece of data from the acquired data; accepts the one piece of data for which the selection is accepted via the screen; and requests the external service system to store information acquired by the device in association with the accepted one piece of data.

Abstract: An information processing system having an information processing apparatus and programs includes an application memory unit storing applications executing a series of processes using electronic data, in which program identification information, parameter setup information, and flow identification information are defined, a use screen memory unit storing use screen information of defining a form; a first receiving unit receiving a first request including the application identification information; a first sending unit sending the use screen information; a second receiving unit, an acquiring unit acquiring the flow information identified by the flow identification information included in the second request, and an executing unit causing the program identified by the flow information to be executed using the parameter included in the second request in conformity with the execution order to execute the series of processes using the electronic data based on the information related to the electronic data.

Abstract: An information processing system includes a device including a browser; and a service providing system including an information processing apparatus. The service providing system includes a manager configured to manage first flow information of a first flow, second flow information of a second flow associated with the first flow, and parameter setting information; and a provider configured to provide, to the device, flow image screen data based on the first and second flow information, and parameter setting screen data based on the parameter setting information of the first and second flow information. The device includes a renderer configured to display a flow image screen based on the flow image screen data and to display a parameter setting screen based on the parameter setting screen data, and accept, from a user at the parameter setting screen, an operation for setting the parameter of the first and second flow information.

Abstract: An information processing system including an information processing apparatus and a service providing system mutually communicating through a network, wherein the information processing apparatus includes a display process unit to cause a screen of a display device to display a process flow that defines an execution order of processes executed by the service providing system, and a setup reception unit to receive a setup, in which predetermined processes related to first and second external services are associated, and the display process unit displays the processes to be executed in the execution order, and an issue that the setup reception unit has received the predetermined processes related to the first and second external services in association with each other, the service providing system includes a process flow execution unit to execute the processes included in the process flow transmitted from the information processing apparatus in the defined execution order.

Abstract: A method of examining a possibility of a subject having pancreatic cancer, including measuring GPRC5C (G protein-coupled receptor family C group 5 member C) present in an exosome in a specimen collected from the subject.

Abstract: An information processing system having an information processing apparatus and programs includes an application memory unit storing applications executing a series of processes using electronic data, in which program identification information, parameter setup information, and flow identification information are defined, a use screen memory unit storing use screen information of defining a form; a first receiving unit receiving a first request including the application identification information; a first sending unit sending the use screen information; a second receiving unit, an acquiring unit acquiring the flow information identified by the flow identification information included in the second request, and an executing unit causing the program identified by the flow information to be executed using the parameter included in the second request in conformity with the execution order to execute the series of processes using the electronic data based on the information related to the electronic data.

Abstract: An information processing system having an information processing apparatus and programs includes an application memory unit storing applications executing a series of processes using electronic data, in which program identification information, parameter setup information, and flow identification information are defined, a use screen memory unit storing use screen information of defining a form; a first receiving unit receiving a first request including the application identification information; a first sending unit sending the use screen information; a second receiving unit, an acquiring unit acquiring the flow information identified by the flow identification information included in the second request, and an executing unit causing the program identified by the flow information to be executed using the parameter included in the second request in conformity with the execution order to execute the series of processes using the electronic data based on the information related to the electronic data.

Abstract: An exosome secretion inhibitor containing a substance suppressing expression of NAPG, HINT3 or GXYLT1 gene, or a substance suppressing activity of NAPG, HINT3 or GXYLT1 protein. It is possible to suppress secretion of exosome, thereby making it possible to suppress proliferation or metastasis of cancer cells, so that the substance suppressing expression of the gene or activity of the protein can be used as an active ingredient of a pharmaceutical composition suitably used in treatment of cancer or suppression of cancer metastasis, and also the substance can provide a carcinostatic agent having a new action mechanism which specifically suppresses expression of the gene or activity of the protein.

Abstract: An information processing system having an information processing apparatus and programs includes an application memory unit storing applications executing a series of processes using electronic data, in which program identification information, parameter setup information, and flow identification information are defined, a use screen memory unit storing use screen information of defining a form; a first receiving unit receiving a first request including the application identification information; a first sending unit sending the use screen information; a second receiving unit, an acquiring unit acquiring the flow information identified by the flow identification information included in the second request, and an executing unit causing the program identified by the flow information to be executed using the parameter included in the second request in conformity with the execution order to execute the series of processes using the electronic data based on the information related to the electronic data.

Abstract: An information processing system having an information processing apparatus and programs includes an application memory unit storing applications executing a series of processes using electronic data, in which program identification information, parameter setup information, and flow identification information are defined, a use screen memory unit storing use screen information of defining a form; a first receiving unit receiving a first request including the application identification information; a first sending unit sending the use screen information; a second receiving unit, an acquiring unit acquiring the flow information identified by the flow identification information included in the second request, and an executing unit causing the program identified by the flow information to be executed using the parameter included in the second request in conformity with the execution order to execute the series of processes using the electronic data based on the information related to the electronic data.

Abstract: An information processing system having an information processing apparatus and programs includes an application memory unit storing applications executing a series of processes using electronic data, in which program identification information, parameter setup information, and flow identification information are defined, a use screen memory unit storing use screen information of defining a form; a first receiving unit receiving a first request including the application identification information; a first sending unit sending the use screen information; a second receiving unit, an acquiring unit acquiring the flow information identified by the flow identification information included in the second request, and an executing unit causing the program identified by the flow information to be executed using the parameter included in the second request in conformity with the execution order to execute the series of processes using the electronic data based on the information related to the electronic data.