Abstract: It is an object to provide an antibody specifically binding to CD37-positive tumor cells such as malignant B-cell lymphoma, an antibody-drug conjugate comprising the antibody, a pharmaceutical composition having therapeutic effects on a tumor using the antibody, a method for treating a tumor using the aforementioned pharmaceutical composition, a method for producing the antibody, and a method for producing the antibody-drug conjugate, and the like. The present invention provides an anti-CD37 antibody-drug conjugate in which an antibody is conjugated to a drug linker represented by the following formula (wherein A represents a connecting position to the antibody) by a thioether bond, specifically, a humanized anti-CD37 antibody having internalization ability and an antibody-drug conjugate containing the antibody.

Abstract: A parking assist method performs a parking assist control of a host vehicle based on a target travel path when a distance between a self-position and a target parking position is determined to be equal to or less than a first predetermined distance, a parking assist permission condition is satisfied, and a shift operation for switching direction has been detected. The parking assist permission condition is satisfied where either a condition in which a predetermined time or longer has elapsed since the host vehicle departed from the target parking position, or a condition in which the distance between the self-position and the target parking position since the host vehicle departed from the target parking position exceeds a second predetermined distance that is equal to or less than the first predetermined distance. The parking assist control is suppressed when the parking assist permission condition is not satisfied.

Abstract: A tofu product production device includes a grinding device that grinds raw soybeans to obtain ground soybeans; an immersion device that immerses the ground soybeans in water to obtain swollen soybeans swollen to at least 1.2 to 2.4 times; and a crushing device that crushes the swollen soybeans to obtain raw soybean paste. The ground soybeans are immersed for a short period of time in the immersion device.

Abstract: A chemically strengthened glass has a thickness of more than 2 mm, a surface compressive stress CS0 of 400 MPa to 1200 MPa, a depth of compressive stress layer DOL-tail of 2.7 ?m to 30.0 ?m, an absolute value of an average slope of a stress profile from a surface to the DOL-tail of 20 MPa/?m to 500 MPa/?m, and a tensile stress CT of 1.0 MPa to 16 MPa.

Abstract: A driving force transmission mechanism is capable of preventing breakage of an oil chamber when the internal pressure in the oil chamber rises by impact when replacing work rolls and the like. The driving force transmission mechanism transmits power of a driving source to a work roll through a spindle and includes a first gear portion disposed on one end portion of the spindle, a second gear part disposed on the driving source or the work roll and fitted to the first gear part and an oil chamber for supplying a lubricating oil to the first gear part and the second gear part, where the oil chamber is provided with a first valve for discharging inner air in the oil chamber to an outside of the oil chamber and a second valve for introducing outer air into the oil chamber.

Abstract: A cleaning blade includes an elastic member that includes a front edge surface extending in the longitudinal direction of the elastic member and the thickness direction orthogonal to the longitudinal direction and a bottom surface extending in the depth direction orthogonal to the longitudinal direction and the thickness direction, the bottom surface sharing a front edge ridge part with the front edge surface and facing a cleaning target, and a coating layer coating the front edge surface, the front edge ridge part, and the bottom surface, wherein the front edge ridge part coated with the coating layer is in contact with a surface of the cleaning target, and the coating layer has an average thickness that increases with an increase in a distance from the front edge ridge part in the thickness direction on the front edge surface.

Abstract: An encoder includes: memory; and circuitry coupled to the memory and configured to generate an encoded bitstream. In the encoder, when a multi-layer structure is to be included in the encoded bitstream to be generated, the circuitry generates the encoded bitstream by including in the encoded bitstream (i) a sequence parameter set that refers to a video parameter set and (ii) a network abstraction layer (NAL) unit having a layer identification (ID) greater than zero in the multi-layer structure, and when the multi-layer structure is not to be included in the encoded bitstream to be generated, the circuitry generates the encoded bitstream by including in the encoded bitstream a sequence parameter set that does not refer to the video parameter set.

Abstract: A nudge management device includes: a storage unit configured to store information of a nudge which is a mechanism for prompting a user to voluntarily adopt a desirable behavior; an acquisition unit configured to acquire nudge intervention information which is information associated with intervention of a nudge; and an abrasion deriving unit configured to derive nudge abrasion information indicating a degree of decrease in effect of the nudge associated with the nudge intervention information based on the nudge intervention information and to output the derived nudge abrasion information.

Abstract: An imaging device according to an embodiment of the present disclosure includes: a plurality of pixel blocks each including a plurality of light-receiving pixels including color filters of same color, the plurality of light-receiving pixels being divided into a plurality of first pixel pairs each including two light-receiving pixels adjacent to each other in a first direction; a plurality of lenses provided at respective positions corresponding to the plurality of first pixel pairs; and a plurality of floating diffusion layers each disposed at a boundary between the two light-receiving pixels, of the plurality of first pixel pairs, adjacent to each other in the first direction, the plurality of floating diffusion layers each shared in the plurality of first pixel pairs.

Abstract: A medical device is disclosed, which is capable of preventing a maintenance treatment element imparting energy to biological tissue from being displaced from a treatment target site and a treatment method performed on a heart failure patient. A medical device is disclosed, which includes a shaft portion, an expandable and contractible expansion body provided on a distal side of the shaft portion, and a maintenance treatment element disposed in the expansion body and imparting energy to biological tissue. The expansion body includes a concave portion recessed in a direction intersecting with an axial direction of the shaft portion. The maintenance treatment element is disposed in the concave portion.

Abstract: The present invention is to provide a compound that further improves the performance of an organic EL device, an organic electroluminescent device having further improved device performance, and an electronic device including such an organic electroluminescent device. Provided is a compound represented by the following formula (1) (the signs in the formula are as defined in the description), an organic electroluminescent device containing the compound, and an electronic device including such an organic electroluminescent device.

Abstract: A simulator capable of communicating with an energy management system (EMS), the simulator including a simulator unit configured to execute a simulation of an algorithm program to be evaluated for the EMS, a performance determination unit configured to determine performance of the algorithm program to be evaluated based on a result of operations of the simulator unit, and a quality determination unit for the simulation unit, wherein an interface for when the algorithm program to be evaluated is incorporated into the simulator and an interface for when the algorithm program to be evaluated is incorporated into the EMS are commonalized.

Abstract: Embodiments provide a pressure sensor capable of surely filling inside of a housing in which an adjustment member is provided with insulating liquid. A base includes a first flow path to be filled with a first fluid and a first recess communicating with the first flow path. A first diaphragm seals the first recess. A sensor unit is provided in the first recess. An adjustment member is arranged around the sensor unit in the first recess, communicates with the first flow path, and includes a hole introducing the first fluid in the first flow path into the first recess. The first diaphragm includes a plurality of grooves arranged concentrically, and the hole is opposed to one of the plurality of grooves.

Abstract: An information processing apparatus for determining an evaluator to evaluate a product or service provided by one of providers from among a plurality of evaluators, the information processing apparatus comprises a controller configured to execute: training a user model, with first data about the providers and second data about the plurality of evaluators who have made evaluations of products or services provided by the providers in past as input data, and third data indicating degrees of usefulness of the evaluations made by the plurality of evaluators in the past as output data; and selecting the evaluator suitable for the one of the providers from among the plurality of evaluators by using the user model.

Abstract: A controlling apparatus capable of controlling radiation imaging by using auto exposure control of a radiation, the controlling apparatus comprising an estimating unit that estimates a radiation dose to be irradiated before the radiation is irradiated from a radiation generating apparatus, and a output unit that outputs information on an estimated radiation dose based on an output from estimating unit, wherein the information on the estimated radiation dose includes: in a case where the auto exposure control is used, information indicating that the auto exposure control is used; and, in a case where the auto exposure control is not used, at least one of the estimated radiation dose and a warning about the radiation.

Abstract: Provided is a testing method using a biomarker for prediction of success or failure of induction of labor, prediction of preterm birth, and prediction of preterm labor, which can be performed with high reliability, simply, and non-invasively. The testing method of the present invention is a testing method using an expression level of 15-PGDH as an index for success or failure of induction of labor, the testing method including a step of detecting the expression level of 15-PGDH in a specimen, the specimen being a vaginal secretion.

Abstract: A film forming method according to one aspect of the present disclosure includes: forming an adsorption-inhibiting region by supplying an adsorption-inhibiting gas to the substrate; adsorbing a silicon-containing gas onto a region excluding the adsorption-inhibiting region; and forming a silicon nitride film by exposing the substrate, onto which the silicon-containing gas has been adsorbed, to plasma generated from a nitriding gas, wherein the nitriding gas includes a nitrogen-containing gas and an inert gas, and the nitrogen-containing gas has a flow rate greater than a flow rate of the inert gas.

Abstract: A silane crosslinkable silicone rubber composition including: with respect to 100 parts by mass of a base rubber containing a millable silicone rubber, 1 to 15 parts by mass of a silane coupling agent graft-bonded to the base rubber; 0.5 to 300 parts by mass of an inorganic filler; and 0.01 to 0.5 parts by mass of a silanol condensation catalyst, a method of producing the same, a silane crosslinked silicone rubber formed body obtained by using the silane crosslinkable silicone rubber composition, and a method of producing the same, and a silane crosslinked silicone rubber formed article including the silane crosslinked silicone rubber formed body.

Abstract: A medical apparatus includes a bendable medical device including a bendable body and a held portion, and an insertion unit including a moving body and a driving portion. The insertion unit is tiltable. The moving body includes a recess portion configured to accommodate the held portion in a case where the bendable medical device is attached to the moving body, a locking member that is movable between a locking position and a release position, and a restriction surface facing the recess portion. In a state in which the held portion is positioned within the recess portion and the tilt angle is maximized, the restriction surface extends upward such that an upper end of the restriction surface is positioned above a lower end of the held portion, and the upper end of the restriction surface forms a lower edge of an opening of the recess portion.

Abstract: A communication device that determines a backoff time of multiband transmission is provided. A communication device includes: a communication unit that transmits and receives wireless signals in a plurality of bands; and a control unit that controls an operation in the communication unit. The control unit sets, for each band, a first random standby time for performing transmission in each of the plurality of bands, sets a second random standby time for performing simultaneous transmission of data in two or more of the plurality of bands, and controls countdown of the second random standby time or the first random standby time of each band on the basis of a comparison between the first random standby time of each band and the second random standby time.