Abstract: A method for producing a brain organoid having an aggregated tau protein including (a) culturing pluripotent stem cells in the presence of a SMAD inhibitor to form an embryoid body, (b) embedding the embryoid body in an extracellular matrix and three-dimensionally culturing the embryoid body in the presence of a SMAD inhibitor and a GSK3? inhibitor to form an organoid that includes neural precursor cells, (c) extracting the organoid from the extracellular matrix and suspension-culturing the organoid in the presence of LIF to form a brain organoid, (d) forcing the brain organoid to express a mutant MAPT gene, and (e) further suspension-culturing the brain organoid after (d) to obtain a brain organoid having an aggregated tau protein.

Abstract: A detection device detecting collapse of PM collected in a filter provided in an exhaust system flow path of an internal combustion engine includes: a differential pressure sensor configured to acquire a differential pressure between an exhaust inlet side and an exhaust outlet side of the filter; a water generation determination unit configured to determine whether water is generated in the exhaust system flow path; and a PM collapse determination unit configured to determine that at least a part of the PM collected in the filter has collapsed when a PM accumulation amount estimated based on the acquired differential pressure has increased by a predetermined amount or more within a predetermined period in a state where the PM accumulation amount estimated based on the acquired differential pressure is equal to or larger than a predetermined first threshold and the water generation determination unit has determined that water is generated.

Abstract: A metal-supported material including a transition metal excluding Group 4 elements supported on a binary composite oxide. The composite oxide includes a metal element expressed by AnXy, where A represents a lanthanoid that is in a partially or entirely trivalent state, X represents an element that is a Group-2 element in a periodic table selected from the group consisting of Ca, Sr, and Ba, or a lanthanoid, and that is different from A, n satisfies 0<n<1, y satisfies 0<y<1, m satisfies 0?m<1, and n+y=1. The composite oxide includes a solid solution that is a tetragonal crystal or a cubic crystal, and a ratio of a value (Dads) of a dispersion degree of the transition metal obtained by an H2 pulse chemical adsorption method to a value (DTEM) of the dispersion degree predicted from an average particle diameter of particles of the transition metal obtained from a TEM image satisfies 0<Dads/DTEM<1.

Abstract: Provided is an electronic pen that includes a body portion housing of an electronic pen body portion has housed therein a refill body and a circuit board having a side switch formed by a push button switch mounted thereon, and has a pen-point opening portion through which a pen point of the refill body protrudes. A pressing member is provided in a side opening portion of the body portion housing such that the pressing member is disposed on the side switch in such a manner as to be prevented by an engagement portion from protruding outwardly from a side surface of the body portion housing. The side switch of the circuit board is operated through the pressing member of the electronic pen body portion when an operation unit of the outer housing having the electronic pen body portion installed therein is pressed.

Abstract: A semiconductor device of an embodiment includes a substrate, a first electrode, a second electrode, the first electrode provided between the substrate and the second electrode, the oxide semiconductor layer in contact with the first electrode, an oxide semiconductor layer between the first electrode and the second electrode, the oxide semiconductor layer contains Zn and at least one first element selected from In, Ga, Si, Al, and Sn; a conductive layer between the oxide semiconductor layer and the second electrode, the conductive layer in contact with the second electrode, the conductive layer contains O and at least one second element selected from the group consisting of In, Ga, Si, Al, Sn, Zn, and Ti, a gate electrode; and a gate insulating layer between the oxide semiconductor layer and the gate electrode.

Abstract: A semiconductor device that can be miniaturized or highly integrated is provided. The semiconductor device includes a transistor and a capacitor. The transistor includes a metal oxide and a first conductor that is electrically connected to the metal oxide. The capacitor includes a first insulator which is provided over the metal oxide and which the first conductor penetrates; a second insulator provided over the first insulator and including an opening reaching the first insulator and the first conductor; a second conductor in contact with an inner wall of the opening, the first insulator, and the first conductor; a third insulator provided over the second conductor; and a fourth conductor provided over the third insulator. The first insulator has higher capability of inhibiting the passage of hydrogen than the second insulator.

Abstract: Provided is an electronic pen stylus including a front-end part which, in operation, comes into contact with a position pointing input surface, and a rod-shaped axial center part formed integrally with the front-end part, in which at least the front-end part is made of a filler-mixed resin of which a base resin is mixed with a fibrous material as the filler having a hardness that is higher than a hardness of the base resin.

Abstract: To provide a controller that can reduce a sense of discomfort felt by a user. A pen-type controller with a grip according to the present disclosure includes a pen part that is formed in a pen shape, a grip part that intersects an axial direction of the pen part, and a battery that is arranged in the grip part.

Abstract: A terminal which is included in a printing system including the terminal device and a printer separately or integrally, the terminal device includes an image generation determination unit configured to determine, when the printer used for printing has a page mode function, an approach for generating a print image for the printing such that use of the page mode function of the printer is given priority; and a command conversion unit configured to convert, when the image generation determination unit determines that the approach for generating the print image uses the page mode function of the printer, print target data to be printed into a command corresponding to the page mode function of the printer.

Abstract: Provided is an electronic pen that includes a body portion housing of an electronic pen body portion has housed therein a refill body and a circuit board having a side switch formed by a push button switch mounted thereon, and has a pen-point opening portion through which a pen point of the refill body protrudes. A pressing member is provided in a side opening portion of the body portion housing such that the pressing member is disposed on the side switch in such a manner as to be prevented by an engagement portion from protruding outwardly from a side surface of the body portion housing. The side switch of the circuit board is operated through the pressing member of the electronic pen body portion when an operation unit of the outer housing having the electronic pen body portion installed therein is pressed.

Abstract: To provide an edge and the like that improve sound quality. The edge includes an edge-shaped portion that is formed from an inner peripheral portion to an outer peripheral portion, and a groove portion that is formed in the edge-shaped portion and has a peak portion and a valley portion, wherein a ridge line of the valley portion of the groove portion extends from a start point on the inner peripheral portion side to an end point on the outer peripheral portion side so as to draw a continuously changing curve.

Abstract: A pen-type controller includes a pen portion having a pen shape, a grip portion that intersects an axis direction of the pen portion, and a first light emitting part disposed at an end part of the grip portion, wherein the end part is closer to the axis of the pen portion than another end part of the grip portion.

Abstract: A negative electrode for an all-solid-state secondary battery according to the present invention includes a molded body made of a negative-electrode mixture containing a solid electrolyte and a negative-electrode material that contains a negative-electrode active material. The negative-electrode material contains a carbon material as the negative-electrode active material, and an argyrodite-type sulfide-based solid electrolyte is contained as the solid electrolyte. An AB value is 0.1 or more and 0.8 or less where a percentage of the area of the carbon material to the area of a surface of the molded body is A(%) and a percentage of the area of the carbon material to the area of a cross-section of the molded body is B(%). Also, an all-solid-state secondary battery according to the present invention includes the negative electrode for an all-solid-state secondary battery according to the present invention as the negative electrode.

Abstract: Disclosed herein is an electronic pen including a cylindrical casing, a first circuit assembly housed in the cylindrical casing, a second circuit assembly housed in the cylindrical casing, and a cable connected to the first circuit assembly and extending from the first circuit assembly toward the second circuit assembly. The cable includes a portion that is bent and folded back toward the first circuit assembly over the second circuit assembly and connected to the second circuit assembly. The portion of the cable that is bent and folded is housed in a housing space between the second circuit assembly and the casing when the first circuit assembly and the second circuit assembly are housed at a fixed position in the cylindrical casing.

Abstract: A current sensor is configured to detect a current flowing through an electrical conductor. The current sensor includes a core and a coil wound around the core. The core has a hollow therein configured to allow the electrical conductor to pass through the hollow. The core substantially has a C-shape having a gap connected to the hollow. The core has a pair of end surfaces facing each other in a facing direction across the gap. The core includes plural split cores joined to one another. Each pair of split cores of the plural split cores adjacent to each other have respective joining surfaces joined to each other. The respective joining surfaces of the each pair of split cores being parallel to the facing direction. This current sensor has a desired sensitivity characteristic.

Abstract: A current sensor is configured to detect a current flowing through an electrical conductor. The current sensor includes a core and a coil wound around the core. The core has a hollow configure to allow the electrical conductor to pass through the hollow. The core substantially has a C-shape haying a gap connected to the hollow. At least a part of the gap of the core is located inside the coil. This current sensor suppresses the influence of external noise.

Abstract: A negative electrode for an all-solid-state secondary battery according to the present invention includes a molded body made of a negative electrode mixture containing a solid electrolyte and a negative-electrode material that contains a negative-electrode active material, in which the negative-electrode material contains a carbon material as the negative-electrode active material, a layer containing an oxide having lithium-ion conductivity is formed on a surface of the negative-electrode material, the amount of the oxide is 1 part by mass or more with respect to 100 parts by mass of the carbon material, and the negative electrode contains a sulfide-based solid electrolyte as the solid electrolyte. Also, an all-solid-state secondary battery according to the present invention includes the negative electrode for an all-solid-state secondary battery according to the present invention as the negative electrode.

Abstract: Provided is an electrochemical element having excellent load characteristics and charge-discharge cycle characteristics, an electrode active material that can constitute the electrochemical element, a method for manufacturing the electrode active material, an electrode material, an electrode, and a movable body including the electrochemical element. The electrode active material for an electrochemical element according to the present invention includes an oxide that has a monoclinic crystal structure and satisfies the following general formula (1): AyM1?Alx??Nb12?x?zM2zO29?? (1). In the general formula (1), A is at least one element selected from Li and Na, M1 is at least one element selected from the group consisting of Fe, Mn, Zn Cu, Ag, Mg Ca, Sr, Ba, Co, Eu, Y, Bi, La, Ce, Nd, Sm, and Gd, M2 is specific element, awl x, y, z, ?, and ? satisfy 0<x?1.1, 0?y?24, 0?z?2, ?1???2, and 0<??0.4x.

Abstract: Provided is an electronic pen that includes a body portion housing of an electronic pen body portion has housed therein a refill body and a circuit board having a side switch formed by a push button switch mounted thereon, and has a pen-point opening portion through which a pen point of the refill body protrudes. A pressing member is provided in a side opening portion of the body portion housing such that the pressing member is disposed on the side switch in such a manner as to be prevented by an engagement portion from protruding outwardly from a side surface of the body portion housing. The side switch of the circuit board is operated through the pressing member of the electronic pen body portion when an operation unit of the outer housing having the electronic pen body portion installed therein is pressed.

Abstract: A driving assist apparatus for a vehicle includes a front-side-environment recognition camera, a front-side-environment recognition sensor, and a control device. The front-side-environment recognition camera is configured to recognize a driving environment ahead of the vehicle. The front-side-environment recognition sensor is configured to recognize the driving environment ahead of the vehicle. In a case where image recognition of the front-side-environment recognition camera for a leading vehicle for adaptive cruise control has deteriorated during execution of the adaptive cruise control, the control device is configured to continue executing the adaptive cruise control based on a distance from the vehicle to the leading vehicle obtained by the front-side-environment recognition sensor.