Patents by Inventor Yutaka Inoki

Yutaka Inoki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triazole derivative or salt thereof
    Patent number: 7776897
    Abstract: There is provided a compound which can be used for therapy of diseases in which 11?-hydroxysteroid dehydrogenase type 1 (11?-HSD1) participates, in particular diabetes, insulin resistance. It has been found that a triazole derivative wherein the triazole ring is substituted with a trisubstituted methyl group in the 2-position or a pharmaceutically acceptable salt thereof has a strong 11?-HSD1 inhibitory activity. Moreover, the triazole derivative of the invention exhibits an excellent blood-glucose level-lowering action and hence can be used for therapy of diabetes, insulin resistance.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: August 17, 2010
    Assignee: Astellas Pharma Inc.
    Inventors: Takeshi Murakami, Tomoaki Kawano, Ryota Shiraki, Hirofumi Ishii, Seiji Yoshimura, Takehiko Ohkawa, Mitsuru Hosaka, Hiroki Fukudome, Yutaka Inoki
  • Triazole Derivative or Salt Thereof
    Publication number: 20070259854
    Abstract: [Problem] There is provided a compound which can be used for therapy of diseases in which 11?-hydroxysteroid dehydrogenase type 1 (11?-HSD1) participates, in particular diabetes, insulin resistance. [Means for Solution] It has been found that a triazole derivative wherein the triazole ring is substituted with a trisubstituted methyl group in the 2-position or a pharmaceutically acceptable salt thereof has a strong 11?-HSD1 inhibitory activity. Moreover, the triazole derivative of the invention exhibits an excellent blood-glucose level-lowering action and hence can be used for therapy of diabetes, insulin resistance.
    Type: Application
    Filed: September 14, 2005
    Publication date: November 8, 2007
    Applicant: ASTELLAS PHARMA INC.
    Inventors: Takeshi Murakami, Tomoaki Kawano, Ryota Shiraki, Hirofumi Ishii, Seiji Yoshimura, Takehiko Ohkawa, Mitsuru Hosaka, Hiroki Fukudome, Yutaka Inoki