Patents by Inventor Yutaka Masutomi

Yutaka Masutomi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphoramidite compound and method for producing oligo-RNA
    Patent number: 8691970
    Abstract: An object of the present invention is to provide a useful and novel phosphoramidite compound for the synthesis of oligo-RNA. A phosphoramidite compound represented by general formula (1), wherein: BX represents a nucleobase optionally having a protecting group; and R1 is a substituent represented by general formula (2), wherein: R11, R12 and R13 are the same or different and each represents hydrogen or alkoxy; R2a and R2b are the same or different and each represents alkyl, or R2a and R2b taken together with the adjacent nitrogen atom may form a 5- to 6-membered saturated amino cyclic group, the amino cyclic group optionally having an oxygen or sulfur atom as a ring-composing member in addition to the adjacent nitrogen atom; and WG1 and WG2 are the same or different and each represents an electron-withdrawing group.
    Type: Grant
    Filed: August 25, 2005
    Date of Patent: April 8, 2014
    Assignee: Nippon Shinyaku Co., Ltd.
    Inventors: Tadaaki Ohgi, Kouichi Ishiyama, Yutaka Masutomi
  • Phosphoramidite Compound And Method For Producing Oligo-Rna
    Publication number: 20070282097
    Abstract: An object of the present invention is to provide a useful and novel phosphoramidite compound for the synthesis of oligo-RNA. A phosphoramidite compound represented by general formula (1), wherein: BX represents a nucleobase optionally having a protecting group; and R1 is a substituent represented by general formula (2), wherein: R11, R12 and R13 are the same or different and each represents hydrogen or alkoxy; R2a and R2b are the same or different and each represents alkyl, or R2a and R2b taken together with the adjacent nitrogen atom may form a 5- to 6-membered saturated amino cyclic group, the amino cyclic group optionally having an oxygen or sulfur atom as a ring-composing member in addition to the adjacent nitrogen atom; and WG1 and WG2 are the same or different and each represents an electron-withdrawing group.
    Type: Application
    Filed: August 25, 2005
    Publication date: December 6, 2007
    Applicant: NIPPON SHINYAKU CO., LTD.
    Inventors: Tadaaki Ohgi, Kouichi Ishiyama, Yutaka Masutomi