Patents by Inventor Yutaka Nakayama
Yutaka Nakayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20060052371Abstract: As prophylactic and/or therapeutic agents for cardiovascular diseases, bone or joint diseases, infectious diseases, inflammatory diseases, kidney diseases, etc. having safe and excellent effects of cell death inhibition, MIF binding, etc., there are provided compounds represented by formula: [wherein, R1 represents a halogen atom, etc., R2 represents a group represented by formula: (wherein, R3 represents hydrogen atom, an optionally substituted alkoxy, etc., R4 represents hydrogen atom, bromine atom, cyano, etc., R5 represents hydrogen atom, hydroxy, etc., R6 represents hydrogen atom, etc., R7 represents hydrogen atom, etc.) etc., and n represents an integer of 0 to 4] or salts thereof.Type: ApplicationFiled: December 4, 2003Publication date: March 9, 2006Inventors: Masahiro Kajino, Yutaka Nakayama, Haruhide Kimura
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Publication number: 20050032786Abstract: This invention provides a compound represented by the formula (I): wherein R1 is a hydrogen atom, a halogen atom, hydroxy, nitro, optionally halogenated alkyl, alkoxy optionally having substituents, acyl or amino optionally having substituents; R2 is pyridyl, furyl, thienyl, pyrrolyl, quinolyl, pyrazinyl, pyrimidinyl, pyridazinyl, indolyl, tetrahydroquinolyl or thiazolyl, each of which may have substituents; n is 1 or 2; or a salt. And this invention provides a safe pharmaceutical comprising the compound of the formula (I), which has an excellent apoptosis inhibitory effect and MIF binding effect, for preventing and/or treating heart disease, nervous degenerative disease, cerebrovascular disease, central nervous infectious disease, traumatorathy, demyelinating disease, bone and articular disease, kidney disease, liver disease, osteomyelodysplasia, AIDS, cancer, and the like.Type: ApplicationFiled: September 2, 2002Publication date: February 10, 2005Inventors: Masahiro Kajino, Akira Kawada, Yutaka Nakayama, Haruhide Kimura
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Patent number: 6308024Abstract: It is a purpose of the invention to provide a dust protector for an image exposure device capable of preventing particles from sticking to windows or the like of the image exposure device and free from moisture condensation on the windows or the like of the image exposure device as a result of direct exposure of the same to the atmosphere and an image forming apparatus utilizing the same. The purpose is achieved by providing a dust protector for an image exposure device for performing image exposure on a member to be exposed from below with a dust protective member for preventing particles from sticking to at least a member located above an optical path of the image exposure device by covering the image exposure device from above without blocking the optical path of the image exposure device and an air flow generating unit for generating an air flow that prevents particles from entering the region covered by the dust protective member.Type: GrantFiled: June 6, 2000Date of Patent: October 23, 2001Assignee: Fuji Xerox Co., Ltd.Inventors: Yutaka Nakayama, Yoshihiko Ichikawa, Masayoshi Nishida, Tomonori Ishikawa, Tohru Hisano, Naoyuki Egusa
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Patent number: 6265586Abstract: A process for producing indolmycin or a salt thereof which comprises reacting a compound of the formula: or a salt thereof with methylamine or a salt thereof, can be produced in an optically active form in a high yield and high quality, and is advantageous from the industrial point of view.Type: GrantFiled: September 25, 2000Date of Patent: July 24, 2001Assignee: Takeda Chemical Industries, Ltd.Inventors: Keiji Kamiyama, Yutaka Nakayama
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Patent number: 6028121Abstract: The present invention provides pre-expanded noncrosslinked polyethylene resin beads which are made of a mixed resin, as a base resin, comprising a high-pressure-process low-density polyethylene, a linear low-density polyethylene, and a linear high-density polyethylene and, when analyzed with a differential scanning calorimeter (DSC), give a fusion endothermic curve which is a mountain-shaped curve having a single peak and in which, when the peak point of the mountain-shaped curve is referred to as A, the point of intersection of the perpendicular line drawn to the temperature axis from A and the base line of the fusion endothermic curve is referred to as B, and the two points at which the straight line drawn through the point C interiorly dividing segment AB in the perpendicular line in a ratio of 9:1 and parallel to the temperature axis intersects the fusion endothermic curve are referred to as D and E, then that temperature width of the mountain-shaped curve part which is the length of segment DE is 15.Type: GrantFiled: May 15, 1998Date of Patent: February 22, 2000Assignee: Asahi Kasei Kogyo Kabushiki KaishaInventors: Noboru Takeda, Yutaka Nakayama
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Patent number: 5654369Abstract: The invention provides a thermoplastic resin composition uniformly and permanently rendered antistatic which comprises (A) 100 parts by weight of a thermoplastic resin, (B) 3-30 parts by weight of a cationic copolymer comprising 80-98 mol % of an ethylene unit and 2-20 mol % of a cationic unit and having a weight-average molecular weight of 1,000-50,000, and (C) 0.Type: GrantFiled: July 22, 1996Date of Patent: August 5, 1997Assignee: Dai-Ichi Kogyo Seiyaku Co., Ltd.Inventors: Takayuki Tsubaki, Yutaka Nakayama, Hideyuki Sumi, Hiroshi Hotta
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Patent number: 5541242Abstract: The present invention provides an antistatic and flame retardant thermoplastic resin composition which comprises [A] 100 weight parts of a thermoplastic resin, [B] 2.0 to 40 weight parts of a bromine-containing organic flame retardant, and [C] 1.0 to 30 weight parts of a (meth)acrylamide-based copolymer and/or a (meth)acrylate ester-based copolymer each comprising 65 to 99 mole percent of an olefin-derived structural unit (I), 0 to 15 mole percent of a (meth)acrylate-derived structural unit (II) and 1 to 35 mole percent of a (meth)acrylamide-derived or (meth)acrylate ester-derived structural unit (III), as arranged linearly, with a weight average molecular weight of 1,000 to 50,000.Type: GrantFiled: July 28, 1994Date of Patent: July 30, 1996Assignee: Dai-Ichi Kogyo Seiyaku Co., Ltd.Inventors: Yutaka Nakayama, Hideyuki Sumi, Hiroshi Hotta
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Patent number: 5332780Abstract: Thermoplastic resin compositions having the following component A-1 or A-2, component B and component C:(A-1): a polymer component having a functional group capable of reacting with an amino group, or(A-2): a composition of component (A-1) and a resin that is non-reactive with an amino group and is different from the resin used in the following component B(B) a thermoplastic resin component that is non-reactive with an amino group under the conditions required to mold the entire resin composition; and(C) a graft copolymer obtained by a graft reaction of a thermoplastic polymer, with a compound (I), or a copolymer having the repeating unit (II) and the repeating unit of an ethylenic unsaturated monomer, ##STR1## wherein R.sup.1 -R.sup.4, the same or different represent a hydrogen atom, an alkyl group, a cycloalkyl group, an aryl group or an aralkyl group.Type: GrantFiled: April 8, 1993Date of Patent: July 26, 1994Assignee: Dai-Ichi Kogyo Seiyaku Co., Ltd.Inventors: Naoki Kitazawa, Manabu Kikuta, Hiroshi Hotta, Yutaka Nakayama, Hideyuki Sumi
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Patent number: 4867765Abstract: A self-discharge type pulse charging electrostatic precipitator includes a high-speed switching element through which the electrical charge stored in a condenser is suddenly supplied to the electrostatic precipitator and the charge is dissipated in an internal resistance in the precipitator. A charging section of the electrostatic precipitator for one power source is divided into a plurality of charging sections which are coupled with each other through inductive elements. The electrostatic precipitator includes a device for supplying the electrical charge to each of the divided charging sections through the high-speed switching element successively in a time sharing manner and a charging capacitor having a capacitance which is substantially equal to a capacitance of the divided charging section. The electrostatic precipitator possesses enhanced precipitation efficiency by suppressing the back ionization and realizes reduction in cost of the power source.Type: GrantFiled: February 25, 1988Date of Patent: September 19, 1989Assignee: Mitsubishi Jukogyo Kabushiki KaishaInventors: Kazutaka Tomimatsu, Yutaka Nakayama
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Patent number: 4792387Abstract: An air-fuel ratio detecting device with which the air-fuel ratio can be accurately detected over the entire range of ratios, both for the lean range and for the rich range. An oxygen pumping element and an oxygen sensing element are arranged opposite one another with a gap therebetween and are disposed in a chamber in which exhaust gas flows. A signal which is symmetric in lean and rich regions is thereby obtained, and this signal is divided into separate portions in the two regions, which are then composed to obtain a single-valued signal accurately representing the air-fuel ratio over the entire operating range.Type: GrantFiled: June 21, 1985Date of Patent: December 20, 1988Assignee: NGK Spark Plug Co., Ltd.Inventors: Toshiyuki Ishihara, Takeshi Kamiya, Yutaka Nakayama, Tetsusyo Yamada
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Patent number: 4785150Abstract: A heater comprising a sheet substrate formed of alumina and an electron-conductive pattern provided thereon and designed to generate heat, in which at least a portion of the electron-conductive pattern is provided thereon with an oxygen ion-conductive layer.Type: GrantFiled: December 6, 1985Date of Patent: November 15, 1988Assignee: NGK Spark Plug So., Ltd.Inventors: Takao Kojima, Nobuhiro Hayakawa, Yutaka Nakayama, Tetsusyo Yamada
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Patent number: 4733102Abstract: An impulse high voltage generator includes a step-up transformer for stepping up a voltage from an AC power source, a thyristor connected with a primary winding of the transformer for controlling the AC voltage from the AC power source by a firing angle, a full-wave rectifier and a capacitor which are connected with a secondary winding of the transformer, and a discharging resistor connected through a high-speed switching element to the secondary winding. The thyristor is turned on at a firing angle in accordance with a frequency which is set by a setting device for setting an impulse high voltage occurence frequency so that the capacitor is charged, while when the thyristor is turned off, the high-speed switching element is turned on to discharge the capacitor so that an impulse high voltage is generated across the discharging resistor. The impulse high voltage generator can vary a peak value and the occurrence frequency of the impulse high voltage simply and inexpensively with high efficiency.Type: GrantFiled: July 22, 1986Date of Patent: March 22, 1988Assignee: Mitsubishi Jukogyo Kabushiki KaishaInventors: Yutaka Nakayama, Kazutaka Tomimatsu
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Patent number: 4733029Abstract: An operating handle locking device for use with an electrical switchgear such as a circuit interrupter comprises a locking plate for blocking the movement of the operating handle between the ON position and the OFF position, and a support plate secured to the circuit interrupter for supporting the lock plate, the locking plate being locked in the operating handle locking position relative to the support plate by a locking member. The switchgear may have a trip button for tripping the switchgear from the exterior, and the locking plate may have a cover portion for covering the trip button when the locking plate is in an operating handle locking position. A cover portion may also be provided in the locking plate for covering the reset button of the circuit interrupter when in the operating handle locking position.Type: GrantFiled: May 20, 1986Date of Patent: March 22, 1988Assignee: Mitsubishi Denki Kabushiki KaishaInventors: Yoshiaki Kobayashi, Yutaka Nakayama
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Patent number: 4629549Abstract: In an oxygen sensor which is provided with an oxygen pump element having electrodes on both front and rear surfaces of a solid electrolyte plate with oxygen ion conductive property, voltage from an external power source is applied between the electrodes and a pumping current flows between the electrodes. Thereby oxygen is pumped out of ambient gases to be measured through a member including a gap with oxygen diffusion limiting property. The limit value of the pumping current accompanied by the oxygen pumping is determined or the oxygen concentration difference produced before and after the diffusive motion of oxygen through the member or oxygen concentration produced after the diffusive motion of oxygen through the member is measured. Thereby the oxygen concentration of the ambient gases is calculated.Type: GrantFiled: July 2, 1985Date of Patent: December 16, 1986Assignee: NGK Spark Plug Co., Ltd.Inventors: Takao Kojima, Yutaka Nakayama, Hiroyuki Ishiguro, Tetsusyo Yamada
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Patent number: 4624770Abstract: The air-fuel-ratio sensor has a mounting body, a cup-shaped protector enclosing a sensitive element, and gas passage holes and deflectors are provided on the protector wall in such a manner that a gas stream outside the sensor generates swirl of the gas in the cup-shaped protector, the amount of the swirling gas increasing with the distance from the mounting body.Type: GrantFiled: May 16, 1985Date of Patent: November 25, 1986Assignee: NGK Spark Plug Co., Ltd.Inventors: Tetsusyo Yamada, Takao Kojima, Hiroyuki Ishiguro, Yutaka Nakayama
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Patent number: 4498968Abstract: The disclosed oxygen sensor has a plate-like oxygen pump element with electrodes, a plate-like oxygen concentration cell element with electrodes, a means to couple the two elements in parallel to each other while forming a gap between those electrodes of the two elements which face with each other, and an oxygen diffusion resistive layer deposited on that electrode of the pump element which faces said gap, whereby said pump element pumps out oxygen from said gap so as to produce such an oxygen partial pressure in the gap under the presence of said oxygen diffusion resistive layer that the oxygen concentration of a gas surrounding the oxygen sensor is detected by coaction of said two elements.Type: GrantFiled: August 23, 1983Date of Patent: February 12, 1985Assignee: NGK Spark Plug Co., Ltd.Inventors: Tetsusyo Yamada, Yutaka Nakayama
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Patent number: 4450065Abstract: The disclosed oxygen sensor has a plate-like oxygen pump element with electrodes, a plate-like oxygen concentration cell element with electrodes, and a means to couple the two elements in parallel to each other while forming a gap between those electrodes of the two elements which face with each other, so that the oxygen concentration cell element measures a ratio between oxygen concentration in said gap and oxygen concentration of a gas surrounding outside of the oxygen sensor, while said oxygen pump element causes diffusion of oxygen between said gap and the outside of the oxygen sensor.Type: GrantFiled: July 26, 1982Date of Patent: May 22, 1984Assignee: NGK Spark Plug Co., Ltd.Inventors: Tetsusyo Yamada, Yutaka Nakayama