Abstract: [Problem] To provide novel compounds that are S1P1 receptor agonists and exhibit an immunosuppressive activities by inducing lymphocyte sequestration in secondary lymphoid tissues. In addition, to provide a pharmaceutical agent which comprises the compounds as an effective component, in particular to provide a therapeutic and/or prophylactic agent for an autoimmune disease and the like.

Abstract: There is provided a retardation film including a stretched film of a polymer film having an absolute value of photoelastic coefficient (m2/N) of 50×10?12 or less measured by using light of a wavelength of 550 nm at 23° C., which satisfies the following expressions (1) and (2): Re[450]<Re[550]<Re[650]??(1) Rth[550]<Re[550]??(2). In the expressions (1) and (2): Re[450], Re[550], and Re[650] respectively represent in-plane retardation values measured by using light of wavelengths of 450 nm, 550 nm, and 650 nm at 23° C.; and Rth[550] represents a thickness direction retardation value measured by using light of a wavelength of 550 nm at 23° C.

Abstract: The object of the present invention is to provide a polymer excellent in transparency and heat resistance. A polymer having at least a repeating unit represented by the following general formula (I): wherein in the general formula (I), R1 denotes a hydrogen atom, a straight-chain or branched alkyl group with a carbon number of 1 to 4, or a substituted or unsubstituted phenyl group; R2, A and B each independently denote a hydrogen atom, a halogen atom, a straight-chain or branched alkyl group with a carbon number of 1 to 4, a straight-chain or branched alkyl halide group with a carbon number of 1 to 4, a straight-chain or branched alkoxy group with a carbon number of 1 to 4, an alkoxycarbonyl group, an acyloxy group, an amino group, an azide group, a nitro group, a cyano group or a hydroxyl group (however, R2 is not a hydrogen atom); and l denotes an integer of 2 or more.

Abstract: The retardation film of the present invention contains a thermoplastic polymer having at least a side chain component (A) oriented in a direction substantially orthogonal to a slow axis, and the absorption edge wavelength (?cut-off) of the side chain component (A) is 330 nm or more, and an in-plane retardation value (Re[450]) at a wavelength of 450 nm is smaller than that (Re[650]) at a wavelength of 650 nm. In the above-mentioned retardation film, the difference (?Re650?450=Re[650]?Re[450]) between the in-plane retardation value (Re[650]) at a wavelength of 650 nm and the in-plane retardation value (Re[450]) at a wavelength of 450 nm is preferably 10 nm or more. The retardation film of the present invention exhibits optical characteristics in which the in-plane birefringence is large and the difference between a retardation value on the short wavelength side and a retardation value on the long wavelength side is large.

Abstract: It is an object to provide a method for producing stable alkaline metal oxide sols having a uniform particle size distribution. The method comprises the steps of: heating a metal compound at a temperature of 60° C. to 110° C. in an aqueous medium that contains a carbonate of quaternary ammonium; and carrying out hydrothermal processing at a temperature of 110° C. to 250° C. The carbonate of quaternary ammonium is (NR4)2CO3 or NR4HCO3 in which R represents a hydrocarbon group, or a mixture thereof. The metal compound is one, or two or more metal compounds selected from a group of compounds based on a metal having a valence that is bivalent, trivalent, or tetravalent.

Abstract: There is provided a method for stably producing metal oxide solid solution particle at low temperature, wherein an alkaline zirconia sol is used as a raw material which is mixed with a metal compound, and then dried and fired. Specifically, there is disclosed a method for producing metal oxide particle (A3) such as zirconia particle in which metal oxides are solid-solubilized, comprising: a step (I) for obtaining metal oxide (A2) sol such as zirconia sol containing a precursor of a metal oxide by mixing an alkaline zirconia (A1) sol which is obtained by a method including a step (i) for heating a zirconium salt (B2) at 60-110° C. in an aqueous medium containing a carbonate of quaternary ammonium and a step (ii) for performing a hydrothermal treatment at 110-250° C.

Abstract: The object of the present invention is to provide an optical film excellent in transparency, heat resistance and processability.

Abstract: A liquid crystal panel of the present invention includes at least a liquid crystal cell, a first polarizer disposed on one side of the liquid crystal cell, a second polarizer disposed on the other side of the liquid crystal cell and a retardation film (A) disposed between the liquid crystal cell and the first polarizer, wherein the retardation film (A) contains a thermoplastic polymer having at least a substituent (a) represented by the following formula (I) and its in-plane retardation value (Re[750]) at a wavelength of 750 nm is larger than its retardation value (Re[550]) at a wavelength of 550 nm. The liquid crystal panel has such an effect that it reduces coloring of characters or images and a color shift even if a screen is viewed from any direction at an angle range of 360°.

Abstract: [Problems to be Solved] To provide a production method of an alkaline zirconia having compatibility of particle properties and binding properties. [Means to Solve the Problems] A production method of an alkaline zirconia sol including: a process (I) in which an alkaline zirconia sol (A) is mixed with a basic zirconium carbonate salt (B1), the alkaline zirconia sol (A) being obtained by: a sub-process (i) in which a zirconium salt (B2) is heated at 60 to 110° C. in an aqueous medium containing a carbonate salt of quaternary ammonium; and a sub-process (ii) in which a hydrothermal treatment is performed at 110 to 250° C. following the sub-process (i). More specifically, a production method of an alkaline zirconia sol including: a process (I) in which an alkaline zirconia sol (A) and a basic zirconium carbonate salt (B1) are mixed in a mass ratio (Bs/As) ranging from 0.05 to 4.

Abstract: A light emitting composition includes a light-emitting iridium-functionalized nanoparticle, such as an organic-inorganic light-emitting iridium-functionalized nanoparticle. A light emitting device includes an anode, a cathode, and a layer containing such a light-emitting composition. In an embodiment, the light emitting device can emit white light.

Abstract: A retardation film according to the present invention consists of a single-layer film in which a birefringent chain polymer is oriented, the polymer having as a repeating unit (A), a structure represented by the following general formula (V): wherein R3 represents a hydrogen atom or an alkyl group having 1 to 8 carbon atoms; R4 and R8 each independently represent a hydrogen atom, a linear or branched alkyl group having 1 to 4 carbon atoms, a linear or branched alkoxyl group having 1 to 4 carbon atoms, a linear or branched thioalkoxyl group having 1 to 4 carbon atoms, halogen, a nitro group, an amino group, a hydroxyl group, or a thiol group (where R4 and R8 are not simultaneously hydrogen atoms); and R5, R6, and R7 each independently represent a hydrogen atom or a substituent.

Abstract: There is provided a liquid crystal panel, in which a color shift in an oblique direction is small even when observed from any azimuth angle of 0° to 360°, and the viewing angle in the horizontal direction is wide.

Abstract: A manufacturing method for a slurry for the production of a precision casting mold that includes a zirconia sol and a refractory powder, and a manufacturing method for a precision casting mold that uses the slurry is provided. The present invention relates to a manufacturing method for a slurry for the production of a precision casting mold for a metal that includes a step in which an alkaline zirconia sol (A1) and a refractory powder (D) are mixed, the alkaline zirconia sol (A1) being obtained by a manufacturing method that includes a step (i), in which a zirconium salt (B1) is heated at 60 to 110° C. in an aqueous medium that includes a carbonate of quaternary ammonium, and a step (ii), in which a hydrothermal treatment is carried out at 100 to 250° C.

Abstract: There is provided an acidic zirconia sol having compatibility of particle properties and binding properties, and a production method of the same. The present invention relates to a production method of an acidic zirconia sol containing zirconia particles having a particle diameter of less than 20 nm in a content of 10 to 50% by mass, based on the mass of all zirconia particles including: a first process in which an alkaline zirconia sol (A) and a zirconium salt (B) are mixed in a mass ratio (Bs/As) ranging from 0.2 to 5.0 of a mass of a solid content (Bs) which is converted into an amount of ZrO2 in the zirconium salt (B) to a mass of a solid content (As) which is converted into an amount of ZrO2 in the alkaline zirconia sol (A); and a second process in which the resultant mixture is reacted at 80 to 250°C. to produce an acidic zirconia sol.

Abstract: A production method of a zirconia sol includes; (A) mixing a dicarboxylic acid compound with a zirconium compound in an aqueous medium, in which a molar ratio of the dicarboxylic acid compound is more than 1 and less than or equal to 10 per mol of zirconium atom in the zirconium compound, and (B) adding 0.7-2.5 mol of a water-soluble organic base per mol of the dicarboxylic acid compound contained in a mixture obtained by the process (A) to the mixture and then treating hydrothermally the resultant mixture.

Abstract: The present invention has an object to provides a lens meter which readily enables alignment of a progressive lens even by an inexperienced examiner.

Abstract: A retardation film comprising a monolayer film having a birefringent chain polymer orientated. The polymer has a repeating unit of the structure of the general formula: (V) wherein R3 is a hydrogen atom or C1-C8 alkyl; each of R4 and R8 independently is a hydrogen atom, C1-C4 linear or branched alkyl, C1-C4 linear or branched alkoxyl, C1-C4 linear or branched thioalkoxyl, halogen, nitro, amino, hydroxyl or thiol (with the proviso that R4 and R8 are not simultaneously hydrogen atoms); and each of R5, R6 and R7 independently is a hydrogen atom or a substituent. This retardation film can be a relatively thin layer, and exhibits such a wavelength dispersion that with respect to light rays of wavelength ? of approximately the entire visible region, the phase contrast is about ?/2 or about ?/4.

Abstract: There is provided a compound exhibiting an activity of suppressing immune response with reduced adverse drug reactions, which compound is useful in the chemotherapy for preventing or treating, for example, a wide range of various autoimmune diseases including systemic erythematodes, chronic rheumatoid arthritis, Type I diabetes, inflammatory bowel disease, biliary cirrhosis, uveitis, multiple sclerosis or other disorders, or chronic inflammatory diseases, or cancers, lymphoma or leukemia, or resistance to organ or tissue transplantation or rejection against transplantation. Novel amine compounds having an S1P1/Edg1 receptor agonist effect, possible stereoisomers or racemic bodies of the compounds, or pharmacologically acceptable salts, hydrates or solvates of the compound, the stereoisomers or the racemic bodies, or prodrugs of the compounds, the stereoisomers, the racemic bodies, the salts, the hydrates or the solvates, are provided.

Abstract: A color purity improving sheet that improves color purity while preventing brightness from degrading due to absorption of light of a necessary color. The color purity improving sheet includes a light-emitting layer containing a light-emitting means for absorbing light in a specific wavelength range other than the target wavelength range and converting its wavelength to emit light in the target wavelength range, and a reflective layer. The light-emitting layer has a transmittance of at least 70% at the maximum absorption wavelength of the light-emitting layer. The light-emitting layer and the reflective layer are laminated together in this order in a direction from which light of a backlight is incident. The reflective layer selectively reflects part of light in the specific wavelength range other than the target wavelength range and has been transmitted without being absorbed by the light-emitting means in the light-emitting layer, allowing entrance into the light-emitting layer again.

Abstract: It is an object to provide a method for producing stable alkaline metal oxide sols having a uniform particle size distribution. The method comprises the steps of: heating a metal compound at a temperature of 60° C. to 110° C. in an aqueous medium that contains a carbonate of quaternary ammonium; and carrying out hydrothermal processing at a temperature of 110° C. to 250° C. The carbonate of quaternary ammonium is (NR4)2CO3 or NR4HCO3 in which R represents a hydrocarbon group, or a mixture thereof. The metal compound is one, or two or more metal compounds selected from a group of compounds based on a metal having a valence that is bivalent, trivalent, or tetravalent.