Patents by Inventor Yutao Xue

Yutao Xue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of making Efavirens and intermediates thereof
    Patent number: 8378143
    Abstract: The present invention provides a process for the preparation of Efavirenz. A compound of Formula 1: may be prepared by a process comprising cyclizing, in the presence of a first base, a compound of Formula 5 with a haloformate of Formula 6. Other processes are also provided as well as novel compounds prepared by and used in such processes.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: February 19, 2013
    Assignee: Apotex Pharmachem Inc.
    Inventors: Bo Chen, Zhi-Xian Wang, Yutao Xue, Lihong Liu, Hao Chen
  • METHODS OF MAKING EFAVIRENS AND INTERMEDIATES THEREOF
    Publication number: 20120095249
    Abstract: The present invention provides a process for the preparation of Efavirenz. A compound of Formula 1: may be prepared by a process comprising cyclizing, in the presence of a first base, a compound of Formula 5 with a haloformate of Formula 6. Other processes are also provided as well as novel compounds prepared by and used in such processes.
    Type: Application
    Filed: December 19, 2011
    Publication date: April 19, 2012
    Applicant: APOTEX PHARMACHEM INC.
    Inventors: Bo CHEN, Zhi-Xian WANG, Yutao XUE, Lihong LIU, Hao CHEN
  • Methods of making efavirenz and intermediates thereof
    Patent number: 8080655
    Abstract: The present invention provides a process for the preparation of Efavirenz. A compound of Formula 1: may be prepared by a process comprising cyclizing, in the presence of a first base, a compound of Formula 5 with a haloformate of Formula 6. Other processes are also provided as well as novel compounds prepared by and used in such processes.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: December 20, 2011
    Assignee: Apotex Pharmachem Inc.
    Inventors: Bo Chen, Zhi-Xian Wang, Yutao Xue, Lihong Liu, Hao Chen
  • METHODS OF MAKING EFAVIRENZ AND INTERMEDIATES THEREOF
    Publication number: 20110015189
    Abstract: The present invention provides a process for the preparation of Efavirenz. A compound of Formula 1 may be prepared by a process comprising cyclizing, in the presence of a first base, a compound of Formula 5 with a haloformate of Formula 6. Other processes are also provided as well as novel compounds prepared by and used in such processes.
    Type: Application
    Filed: July 20, 2009
    Publication date: January 20, 2011
    Applicant: APOTEX PHARMACHEM INC.
    Inventors: Bo CHEN, Zhi-Xian WANG, Yutao XUE, Lihong LIU, Hao CHEN