Patents by Inventor Yuto UNOH

Yuto UNOH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triazine derivatives having virus replication inhibitory activity and pharmaceutical composition comprising the same
    Patent number: 11814368
    Abstract: The present invention provides a compound exhibiting coronavirus 3 CL protease inhibitory activity or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same. Furthermore, the present invention provides a crystalline form useful as an active pharmaceutical ingredient, and a pharmaceutical composition comprising the same. A compound represented by Formula: or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: November 14, 2023
    Assignees: SHIONOGI & CO., LTD., NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
    Inventors: Yuki Tachibana, Shota Uehara, Yuto Unoh, Kenji Nakahara, Yoshiyuki Taoda, Yukiko Yamatsu, Shigeru Ando, Michihito Sasaki
  • POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE
    Publication number: 20230227454
    Abstract: The present invention provides a compound represented by Formula (I): wherein ring A is a substituted or unsubstituted heterocycle; ring C is a benzene ring or the like; R1 is halogen or the like; R2a and R2b are each independently hydrogen or the like; R3 is substituted or unsubstituted alkyl or the like; R4 is hydrogen or the like; and n is an integer of 1 to 3.
    Type: Application
    Filed: March 22, 2023
    Publication date: July 20, 2023
    Applicant: Shionogi & Co., Ltd.
    Inventors: Yoshiyuki TAODA, Yuto UNOH
  • TRIAZINE DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
    Publication number: 20230212154
    Abstract: The present invention provides a compound exhibiting coronavirus 3CL protease inhibitory activity or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same. Furthermore, the present invention provides a crystalline form useful as an active pharmaceutical ingredient, and a pharmaceutical composition comprising the same. A compound represented by Formula: , or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 29, 2022
    Publication date: July 6, 2023
    Applicants: Shionogi & Co., Ltd., NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
    Inventors: Yuki TACHIBANA, Shota UEHARA, Yuto UNOH, Kenji NAKAHARA, Yoshiyuki TAODA, Yukiko YAMATSU, Shigeru ANDO, Michihito SASAKI
  • Polycyclic carbamoylpyridone derivative
    Patent number: 11649236
    Abstract: The present invention provides a compound represented by Formula (I): wherein ring A is a substituted or unsubstituted heterocycle; ring C is a benzene ring or the like; R1 is halogen or the like; R2a and R2b are each independently hydrogen or the like; R3 is substituted or unsubstituted alkyl or the like; R4 is hydrogen or the like; and n is an integer of 1 to 3.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: May 16, 2023
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Yoshiyuki Taoda, Yuto Unoh
  • TRIAZINE DERIVATIVES HAVING VIRUS REPLICATION INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
    Publication number: 20230128162
    Abstract: The present invention provides a compound exhibiting coronavirus 3CL protease inhibitory activity or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same. Furthermore, the present invention provides a crystalline form useful as an active pharmaceutical ingredient, and a pharmaceutical composition comprising the same. A compound represented by Formula (I): wherein Y is N or the like; R1 is substituted or unsubstituted aromatic heterocyclyl or the like; R2 is substituted or unsubstituted aromatic carbocyclyl or the like; R3 is substituted or unsubstituted aromatic heterocyclyl or the like; —X— is —NH— or the like; m is 1 or the like; R5a is each independently a hydrogen atom or the like; R5b is each independently a hydrogen atom or the like; n is 1 or the like; R4a is each independently a hydrogen atom or the like; and R4b is each independently a hydrogen atom or the like, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 17, 2022
    Publication date: April 27, 2023
    Applicants: Shionogi & Co., Ltd., NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
    Inventors: Yuki TACHIBANA, Shota UEHARA, Yuto UNOH, Kenji NAKAHARA, Yoshiyuki TAODA, Koji KASAMATSU, Yukiko YAMATSU, Shigeru ANDO, Atsuhiro IIMURO, Takahiro SUTO, Michihito SASAKI
  • POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE
    Publication number: 20210122751
    Abstract: The present invention provides a compound represented by Formula (I): wherein ring A is a substituted or unsubstituted heterocycle; ring C is a benzene ring or the like; R1 is halogen or the like; R2a and R2b are each independently hydrogen or the like; R3 is substituted or unsubstituted alkyl or the like; R4 is hydrogen or the like; and n is an integer of 1 to 3.
    Type: Application
    Filed: May 30, 2019
    Publication date: April 29, 2021
    Applicant: Shionogi & Co., Ltd.
    Inventors: Yoshiyuki TAODA, Yuto UNOH