Abstract: Example error correction methods and apparatus are described. In one example method, a register controller detects an error existing in a memory, and after detecting an uncorrected error (UCE), obtains a memory address in which the UCE occurs. The register controller reads raw data from a location indicated by the memory address, stores preset first data in the location indicated by the memory address, and reads second data from the location after storing the first data in the location. The register controller compares the first data with the second data to determine a first failure location in the location, determines raw data stored in the first failure location from the raw data in the location, and performs error correction on the raw data stored in the first failure location.

Abstract: The present disclosure relates to a method, a device and a medium for performing vessel segmentation in a medical image. The method may comprise acquiring a medical image for vessel segmentation containing multiple parts, each of which contains vessels with different structural attributes. The method may comprise dividing the medical image into sub-medical images according to the parts by using a processor. The method may comprise determining individual vessel segmentation result for each part by means of using the vessel segmentation model corresponding to the part based on the sub-medical image of the part by using the processor. The method may comprise obtaining a vessel segmentation result of the medical image by means of fusing the individual vessel segmentation results of the sub-medical images of the parts by the processor.

Abstract: The present disclosure relates in some aspects to methods and compositions for in situ detection of an analyte in a biological sample embedded in a matrix that is attached to metal nanoparticles. In some embodiments, the detection involves generation of a fluorescent signal that is enhanced by the metal nanoparticles. The fluorescent signal can be detected at a 3-dimensional (3D) location in the matrix which corresponds to the 3D location of the analyte in the biological sample.

Abstract: The present disclosure relates to a training method and a training system for training a learning network for medical image analysis. The training method includes: acquiring an original training data set for a learning network with a predetermined structure; performing, by a processor, a pre-training on the learning network using the original training data set to obtain a pre-trained learning network; evaluating, by the processor, the pre-trained learning network to determine whether the pre-trained learning network has an evaluation defect; when the pre-trained learning network has the evaluation defect, performing, by the processor, a data augmentation on the original training data set for the existing evaluation defect; and performing, by the processor, a refined training on the pre-trained learning network using a data augmented training data set.

Abstract: Described herein are methods and non-transitory computer-readable media configured to obtain a plurality of images from a plurality of image scanning orientations for an object. A rigid registration is performed to the plurality of images to obtain a transformation matrix to normalize the plurality of images from their respective image spaces to a normalized image space. Each normalized image comprises a plurality of voxels. A machine learning model comprising an implicit representation of a high-resolution image is trained using the normalized images, wherein the high-resolution image comprises more voxels than the voxels in the normalized images. The high-resolution image is generated based on the trained machine learning model. The plurality of images are a plurality of anisotropic 2D images, while the high resolution image can be a 2D or 3D high resolution image.

Abstract: The present disclosure relates in some aspects to methods and compositions for assessing system performance for in situ analyte detection. In some aspects, performance of an individual instrument can be assessed, or the performance of two or more instruments can be assessed and optionally compared. In some aspects, disclosed herein is a method comprising using rolling circle amplification products (RCPs) deposited on a cell-free and tissue-free quality control (QC) slide to assess performance of instrument workflow, where an instrument is used to decode signals associated with the RCPs on the QC slide. Quality metrics associated with the decoding (e.g., a percentage of RCPs successfully decoded to genes) can be used to qualify a system comprising the instrument and reagents for in situ analyte detection in cells or tissue samples, e.g., using in situ probe hybridization or in situ sequencing performed on the instrument.

Abstract: A 3D printing apparatus and method includes a piezo actuator that reciprocates a tappet. The reciprocation of the tappet generates pressure within a chamber filled with molten print material. The generated pressure causes the molten print material to be extruded through a nozzle coupled to the chamber. The piezo actuator is controlled to switchably provide continuous extrusion of print material or extrusion of discrete droplets of print material.

Abstract: Example error correction methods and apparatus are described. In one example method, a register controller detects an error existing in a memory, and after detecting an uncorrected error (UCE), obtains a memory address in which the UCE occurs. The register controller reads raw data from a location indicated by the memory address, stores preset first data in the location indicated by the memory address, and reads second data from the location after storing the first data in the location. The register controller compares the first data with the second data to determine a first failure location in the location, determines raw data stored in the first failure location from the raw data in the location, and performs error correction on the raw data stored in the first failure location.

Abstract: A computer-implemented method for predicting a blood vessel stenosis is disclosed. The method may include extracting a blood vessel path and its centerline based on the image of the blood vessel. The method may further include determining a candidate stenosis for the blood vessel path and identifying image blocks along the centerline of the blood vessel path within a range of candidate stenosis for the blood vessel path determined based on the candidate stenosis. The method may also include determining a degree of stenosis for the blood vessel path by applying a trained learning network comprising a convolutional neural network and a recurrent neural network on the image blocks within the range of candidate stenosis.

Abstract: The present disclosure relates to a method, a device and a medium for performing vessel segmentation in a medical image. The method may comprise acquiring a medical image for vessel segmentation containing multiple parts, each of which contains vessels with different structural attributes. The method may comprise dividing the medical image into sub-medical images according to the parts by using a processor. The method may comprise determining individual vessel segmentation result for each part by means of using the vessel segmentation model corresponding to the part based on the sub-medical image of the part by using the processor. The method may comprise obtaining a vessel segmentation result of the medical image by means of fusing the individual vessel segmentation results of the sub-medical images of the parts by the processor.

Abstract: Method, system, device and medium for determining a blood flow velocity in a vessel are provided. An example method includes receiving a 3D model of the vessel, which is reconstructed based on X-ray angiography images of the vessel. The method further includes specifying a segment of the 3D model by a start landmark and a termination landmark. Moreover, the method includes determining the blood flow velocity based on length of the segment and perfusion time for the segment by normalizing the blood flow velocity to correspond to a cardiac cycle. The method has a better accuracy in calculating blood flow velocity, and requires no additional modalities other than the original X-ray angiogram sequences used to visualize coronary arteries.

Abstract: The disclosure relates to systems and methods for evaluating a blood vessel. The method includes receiving image data of the blood vessel acquired by an image acquisition device, and predicting, by a processor, blood vessel condition parameters of the blood vessel by applying a deep learning model to the acquired image data of the blood vessel. The deep learning model maps a sequence of image patches on the blood vessel to blood vessel condition parameters on the blood vessel, where in the mapping the entire sequence of image patches contribute to the blood vessel condition parameters. The method further includes providing the blood vessel condition parameters of the blood vessel for evaluating the blood vessel.

Abstract: The present disclosure relates to a training method and a training system for training a learning network for medical image analysis. The training method includes: acquiring an original training data set for a learning network with a predetermined structure; performing, by a processor, a pre-training on the learning network using the original training data set to obtain a pre-trained learning network; evaluating, by the processor, the pre-trained learning network to determine whether the pre-trained learning network has an evaluation defect; when the pre-trained learning network has the evaluation defect, performing, by the processor, a data augmentation on the original training data set for the existing evaluation defect; and performing, by the processor, a refined training on the pre-trained learning network using a data augmented training data set.

Abstract: The present disclosure relates to a medical image analysis method, a medical image analysis device, and a computer-readable storage medium. The medical image analysis method includes receiving a medical image acquired by a medical imaging device; determining a navigation trajectory by performing navigation processing on the medical image based on an analysis requirement, the analysis requirement indicating a disease to be analyzed; extracting an image block set along the navigation trajectory; extracting image features using a first learning network based on the image block set; and determining an analysis result using a second learning network based on the image features and the navigation trajectory.

Abstract: The present disclosure relates to a medical image analysis method, a medical image analysis device, and a computer-readable storage medium. The medical image analysis method includes receiving a medical image acquired by a medical imaging device; determining a navigation trajectory by performing navigation processing on the medical image based on an analysis requirement, the analysis requirement indicating a disease to be analyzed; extracting an image block set along the navigation trajectory; extracting image features using a first learning network based on the image block set; and determining an analysis result using a second learning network based on the image features and the navigation trajectory.

Abstract: A computer-implemented method for predicting a blood vessel stenosis is disclosed. The method may include extracting a blood vessel path and its centerline based on the image of the blood vessel. The method may further include determining a candidate stenosis for the blood vessel path and identifying image blocks along the centerline of the blood vessel path within a range of candidate stenosis for the blood vessel path determined based on the candidate stenosis. The method may also include determining a degree of stenosis for the blood vessel path by applying a trained learning network comprising a convolutional neural network and a recurrent neural network on the image blocks within the range of candidate stenosis.

Abstract: The present disclosure provides a prediction method for a healthy radius of a blood vessel path, a prediction method for candidate stenosis of a blood vessel path, and a blood vessel stenosis degree prediction device. The prediction method for a healthy radius includes: obtaining a blood vessel radius of the blood vessel path; by a processor, detecting a radius peak of the blood vessel radius of the blood vessel path; and by the processor, predicting the healthy radius of the blood vessel path by performing a regression on the radius peak of the blood vessel radius. The blood vessel stenosis degree prediction device can, in certain embodiments, automatically determine the candidate stenosis and detect the degree of stenosis for the candidate stenosis range, significantly reduce the computation load, improve the detection efficiency and effectively avoid missed detection.

Abstract: The present disclosure relates to a method, storage medium, and system for analyzing an image sequence of a periodic physiological activity. In one implementation, the method includes receiving the image sequence acquired by an imaging device, the image sequence having a plurality of frames, and identifying a feature point in a first frame. The method further includes determining motion vectors for the feature point in the frames of the image sequence. Each motion vector for the feature point is determined based on respective locations of corresponding feature points in frames adjacent to the first frame. The method also includes determining a motion magnitude profile based on the determined motion vectors and determining a phase of each frame in the image sequence based on the motion magnitude profile.

Abstract: The disclosure relates to systems and methods for evaluating a blood vessel. The method includes receiving image data of the blood vessel acquired by an image acquisition device, and predicting, by a processor, blood vessel condition parameters of the blood vessel by applying a deep learning model to the acquired image data of the blood vessel. The deep learning model maps a sequence of image patches on the blood vessel to blood vessel condition parameters on the blood vessel, where in the mapping the entire sequence of image patches contribute to the blood vessel condition parameters. The method further includes providing the blood vessel condition parameters of the blood vessel for evaluating the blood vessel.

Abstract: The disclosure relates to systems and methods for determining blood vessel conditions. The method includes receiving a sequence of image patches along a blood vessel path acquired by an image acquisition device. The method also includes predicting a sequence of blood vessel condition parameters on the blood vessel path by applying a trained deep learning model to the acquired sequence of image patches on the blood vessel path. The deep learning model includes a data flow neural network, a recursive neural network and a conditional random field model connected in series. The method further includes determining the blood vessel condition based on the sequence of blood vessel condition parameters. The disclosed systems and methods improve the calculation of the sequence of blood vessel condition parameters through an end-to-end training model, including improving the calculation speed, reducing manual intervention for feature extraction, increasing accuracy, and the like.