Abstract: The present disclosure relates to a medical silicon rubber having high mechanical property and a preparation method thereof. The medical silicon rubber comprises the following raw materials in parts by weight: 50˜90 parts of silicon rubber, 10˜50 parts of polyurethane, 10˜50 parts of fillers, 2˜6 parts of hydrogen-containing silicon oil and 2˜5 parts of a vulcanizing agent. The preparation method comprises: evenly mixing a part of fillers with silicon rubber in an internal mixer, and evenly mixing the other part of fillers with polyurethane in the internal mixer; and mixing the mixed polyurethane on an open type rubber refining machine, then successively adding hydrogen-containing silicon oil, the evenly mixed silicon rubber and the vulcanizing agent into the open type rubber refining machine many times by small portions, and finally vulcanizing the mixed rubber on a plate rubber vulcanizing machine for 5˜15 min at 150˜190° C.

Abstract: Disclosed is a degradable zinc base alloy implant material comprising, by mass percentage content, 0.01 wt % to 14 wt % of Fe, 0 wt % to 13 wt % of functional elements and the remainder being Zn and a preparation method and use thereof. During preparation, Zn, Fe, and the functional elements are homogeneously mixed and placed into a high-purity graphite crucible and smelted together under a mixed gas atmosphere of SF6 and CO2. The mechanical properties of the zinc base alloy implant material have been significantly improved, so that the implant material is easy to process and shape, and so that the properties of strength and plasticity, etc., meet the basic requirements of human body implant materials, such as vascular stents, orthopedic internal fixation systems, and the like.

Abstract: The disclosure provides a medical sealant glue capable of promoting wound healing and a preparation method thereof. The medical sealant glue is formed by covalent cross-linking of two components after being physically mixed by a mixing tool, wherein the first component is a nucleophilic component, and the second component is an electrophilic component. The medical sealant glue has a gelation time of 1-10 s, a swelling ratio of 0-100%, a bursting strength of 100-250 mmHg, and a degradation time of 0.5-300 days. The nucleophilic component of the medical sealant glue contains exosome or hyaluronic acid and chitosan, and thus the medical sealant glue not only has the effect of promoting wound healing, but also has antibacterial and anti-infection effects.

Abstract: The present disclosure relates to a medical silicon rubber having high mechanical property and a preparation method thereof. The medical silicon rubber comprises the following raw materials in parts by weight: 50˜90 parts of silicon rubber, 10˜50 parts of polyurethane, 10˜50 parts of fillers, 2˜6 parts of hydrogen-containing silicon oil and 2˜5 parts of a vulcanizing agent. The preparation method comprises: evenly mixing a part of fillers with silicon rubber in an internal mixer for later use, and evenly mixing the other part of fillers with polyurethane in the internal mixer; and mixing the mixed polyurethane on an open type rubber refining machine, then successively adding hydrogen-containing silicon oil, the evenly mixed silicon rubber and the vulcanizing agent into the open type rubber refining machine many times by small portions, and finally vulcanizing the mixed rubber on a plate rubber vulcanizing machine for 5˜15 min at 150˜190° C.

Abstract: The disclosure provides a medical sealant glue capable of promoting wound healing and a preparation method thereof. The medical sealant glue is formed by covalent cross-linking of two components after being physically mixed by a mixing tool, wherein the first component is a nucleophilic component, and the second component is an electrophilic component. The medical sealant glue has a gelation time of 1-10 s, a swelling ratio of 0-100%, a bursting strength of 100-250 mmHg, and a degradation time of 0.5-300 days. The nucleophilic component of the medical sealant glue contains exosome or hyaluronic acid and chitosan, and thus the medical sealant glue not only has the effect of promoting wound healing, but also has antibacterial and anti-infection effects.

Abstract: A porous bionic skull repairing material includes a polymer material, whose structure is consistent with that of a human skull. The surface layers of the porous bionic skull repairing material are dense layers which are composed of non-degradable or degradable polymer materials and has blind holes having an asymmetric structure, and the inner layer of the porous bionic skull repairing material is a loose layer which has a porous structure. The repairing material can be molded by adopting a mixed mould pressing method or a 3D printing method, simulates a bone structure, with two dense sides and a loose middle, of a human skull to the greatest extent.

Abstract: A method for preparing a degradable drug-loaded microsphere for embolization and a product obtained therefrom, includes the steps of: dissolving a degradable material in an organic solvent, then adding a drug and mixing well to form a suspension or solution; then pouring the drug-containing suspension or solution into an aqueous solution of polyvinyl alcohol, stirring, and thereafter adding water twice for dilution, to prepare the degradable drug-loaded microsphere. The microsphere prepared by the present invention has the advantages of having a controllable particle size, a high drug loading capacity, and a regular spherical shape, being convenient for sieve sizing and accurate particle-size indication, and being accurately targeted to an embolized blood vessel, and the like, and thus has a good application prospect in interventional embolization therapy.

Abstract: A porous bionic skull repairing material includes a polymer material, whose structure is consistent with that of a human skull. The surface layers of the porous bionic skull repairing material are dense layers which are composed of non-degradable or degradable polymer materials and has blind holes having an asymmetric structure, and the inner layer of the porous bionic skull repairing material is a loose layer which has a porous structure. The repairing material can be molded by adopting a mixed mould pressing method or a 3D printing method, simulates a bone structure, with two dense sides and a loose middle, of a human skull to the greatest extent.

Abstract: A method for preparing a degradable drug-loaded microsphere for embolization and a product obtained therefrom, includes the steps of: dissolving a degradable material in an organic solvent, then adding a drug and mixing well to form a suspension or solution; then pouring the drug-containing suspension or solution into an aqueous solution of polyvinyl alcohol, stirring, and thereafter adding water twice for dilution, to prepare the degradable drug-loaded microsphere. The microsphere prepared by the present invention has the advantages of having a controllable particle size, a high drug loading capacity, and a regular spherical shape, being convenient for sieve sizing and accurate particle-size indication, and being accurately targeted to an embolized blood vessel, and the like, and thus has a good application prospect in interventional embolization therapy.

Abstract: Disclosed is a degradable zinc base alloy implant material comprising, by mass percentage content, 0.01 wt % to 14 wt % of Fe, 0 wt % to 13 wt % of functional elements and the remainder being Zn and a preparation method and use thereof. During preparation, Zn, Fe, and the functional elements are homogeneously mixed and placed into a high-purity graphite crucible and smelted together under a mixed gas atmosphere of SF6 and CO2. The mechanical properties of the zinc base alloy implant material have been significantly improved, so that the implant material is easy to process and shape, and so that the properties of strength and plasticity, etc., meet the basic requirements of human body implant materials, such as vascular stents, orthopedic internal fixation systems, and the like.

Abstract: This patent invents a heat-resistant isotropic bonded NdFeB magnet and its preparation technology, belonging to the field of magnetic materials. In present invention, isotropic NdFeB magnetic powders is used as magnetic material, sodium silicate is used as principal binder, and epoxy resin is used as auxiliary binder to prepare heat-resistant isotropic bonded NdFeB magnets. The prepared magnets have greatly increased heat resistance to stand an operating temperature of 200° C., and have advantages of penetration and corrosion resistance. The invented heat-resistant isotropic bonded NdFeB magnets feature good magnetic properties and high operating temperature. During the preparation process, it has the advantage of simple equipment, easy operation, low cost. The technology is easy to large scale production, and has high economic value and huge application prospect in the field of permanent magnetic materials.

Abstract: This patent invents a heat-resistant isotropic bonded NdFeB magnet and its preparation technology, belonging to the field of magnetic materials. In present invention, isotropic NdFeB magnetic powders is used as magnetic material, sodium silicate is used as principal binder, and epoxy resin is used as auxiliary binder to prepare heat-resistant isotropic bonded NdFeB magnets. The prepared magnets have greatly increased heat resistance to stand an operating temperature of 200° C., and have advantages of penetration and corrosion resistance. The invented heat-resistant isotropic bonded NdFeB magnets feature good magnetic properties and high operating temperature. During the preparation process, it has the advantage of simple equipment, easy operation, low cost. The technology is easy to large scale production, and has high economic value and huge application prospect in the field of permanent magnetic materials.