Patents by Inventor Yuxiang Dong
Yuxiang Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220246337Abstract: The present disclosure discloses a sintered neodymium-iron-boron magnet and a preparation method thereof. The sintered neodymium-iron-boron magnet includes the following raw materials in mass percentage: 1%-40% of an iron powder or a steel powder with a magnetic induction intensity of more than 1.2 T, not more than 10% of a praseodymium-neodymium metal hydride powder, and a remainder of a neodymium-iron-boron fine powder, wherein the mass percentages of the above raw materials add up to 100%. The preparation method includes: weighing the raw materials in mass percentage; mixing the weighed raw materials uniformly, and then subjecting to magnetic-field press molding, isostatic pressing, sintering and tempering to obtain the sintered neodymium-iron-boron magnet.Type: ApplicationFiled: November 20, 2021Publication date: August 4, 2022Inventors: Yujun ZENG, Minglei HAN, Zhaoyong LIU, Xueliang ZHANG, Zhigang XUE, Quanjin ZENG, Yuxiang DONG, Junxing ZHAO, Lan FENG, Ze LIU, Xia ZHANG, Jialiang ZHANG, Xiangjun CHEN
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Patent number: 8067620Abstract: A means and method for treating malaria, schistosomiasis, and cancer using a spiro or dispiro 1,2,4-trioxolane is described. The preferred 1,2,4-trioxolanes include a spiroadamantane group on one side of the trioxolane group, and a spirocyclohexyl on the other side of the trioxolane group. In comparison to artemisinin semisynthetic derivatives, the compounds of this invention are structurally simple, easy to synthesize, non-toxic, and potent against malarial parasites. The compounds of the invention unexpectedly provide a single-dose cure for malaria, as well as prophylactic activity against the same. The compounds are also active against schistosomiasis and cancer.Type: GrantFiled: October 31, 2007Date of Patent: November 29, 2011Assignee: Medicines for Malaria Venture MMVInventors: Jonathan L. Vennerstrom, Yuxiang Dong, Susan A. Charman, Sergio Wittlin, Jacques Chollet, Darren J. Creek, Xiaofang Wang, Kamaraj Spiraghavan, Lin Zhou, Hugues Matile, William N. Charman
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Publication number: 20080125441Abstract: A means and method for treating malaria, schistosomiasis, and cancer using a Spiro or dispiro 1,2,4-trioxolane is described. The preferred 1,2,4-trioxolanes include a spiroadamantane group on one side of the trioxolane group, and a spirocyclohexyl on the other side of the trioxolane group, whereby the spirocyclohexyl ring is preferably substituted at the 4-position. In comparison to artemisinin semisynthetic derivatives, the compounds of this invention are structurally simple, easy to synthesize, non-toxic, and potent against malarial parasites.Type: ApplicationFiled: October 31, 2007Publication date: May 29, 2008Applicant: MEDICINES FOR MALARIA VENTURE MMVInventors: JONATHAN L. VENNERSTROM, YUXIANG DONG, SUSAN A. CHARMAN, SERGIO WITTLIN, JACQUES CHOLLET, XIAOFANG WANG, KAMARAJ SRIRAGHAVAN, LIN ZHOU, HUGUES MATILE, WILLIAM N. CHARMAN
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Publication number: 20080125411Abstract: A means and method for treating malaria, schistosomiasis, and cancer using a spiro or dispiro 1,2,4-trioxolane is described. The preferred 1,2,4-trioxolanes include a spiroadamantane group on one side of the trioxolane group, and a spirocyclohexyl on the other side of the trioxolane group. In comparison to artemisinin semisynthetic derivatives, the compounds of this invention are structurally simple, easy to synthesize, non-toxic, and potent against malarial parasites. The compounds of the invention unexpectedly provide a single-dose cure for malaria, as well as prophylactic activity against the same. The compounds are also active against schistosomiasis and cancer.Type: ApplicationFiled: October 31, 2007Publication date: May 29, 2008Applicant: MEDICINES FOR MALARIA VENTURE MMVInventors: JONATHAN L. VENNERSTROM, YUXIANG DONG, SUSAN A. CHARMAN, SERGIO WITTLIN, JACQUES CHOLLET, DARREN J. CREEK, XIAOFANG WANG, KAMARAJ SRIRAGHAVAN, LIN ZHOU, HUGUES MATILE, WILLIAM N. CHARMAN
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Patent number: 7371778Abstract: A means and method for treating malaria, schistosomiasis, and cancer using a spiro or dispiro 1,2,4-trioxolane is described. The preferred 1,2,4-trioxolanes include a spiroadamantane group on one side of the trioxolane group, and a spirocyclohexyl on the other side of the trioxolane group, whereby the spirocyclohexyl ring is preferably substituted at the 4-position. In comparison to artemisinin semisynthetic derivatives, the compounds of this invention are structurally simple, easy to synthesize, non-toxic, and potent against malarial parasites.Type: GrantFiled: May 4, 2005Date of Patent: May 13, 2008Assignee: Medicines for Malaria Venture MMVInventors: Jonathan L. Vennerstrom, Yuxiang Dong, Jacques Chollet, Hugues Matile, Xiaofang Wang, Kamaraj Spiraghavan, William N. Chapman
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Publication number: 20050256185Abstract: A means and method for treating malaria, schistosomiasis, and cancer using a spiro or dispiro 1,2,4-trioxolane is described. The preferred 1,2,4-trioxolanes include a spiroadamantane group on one side of the trioxolane group, and a spirocyclohexyl on the other side of the trioxolane group, whereby the spirocyclohexyl ring is preferably substituted at the 4-position. In comparison to artemisinin semisynthetic derivatives, the compounds of this invention are structurally simple, easy to synthesize, non-toxic, and potent against malarial parasites.Type: ApplicationFiled: May 4, 2005Publication date: November 17, 2005Applicant: MEDICINES FOR MALARIA VENTURE MMVInventors: Jonathan Vennerstrom, Yuxiang Dong, Jacques Chollet, Hugues Matile, Xiaofang Wang, Kamaraj Sriraghavan, William Charman
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Patent number: 6906205Abstract: A means and method for treating malaria, schistosomiasis, and cancer using a spiro or dispiro 1,2,4-trioxolane is described. The preferred 1,2,4-trioxolanes include a spiroadamantane group on one side of the trioxolane group, and a spirocyclohexyl on the other side of the trioxolane group, whereby the spirocyclohexyl ring is preferably substituted at the 4-position. In comparison to artemisinin semisynthetic derivatives, the compounds of this invention are structurally simple, easy to synthesize, non-toxic, and potent against malarial parasites.Type: GrantFiled: December 19, 2003Date of Patent: June 14, 2005Assignee: Medicines for Malaria Venture MMVInventors: Jonathan L. Vennerstrom, Yuxiang Dong, Jacques Chollet, Hugues Matile, Maniyan Padmanilayam, Yuangqing Tang, William N. Charman
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Patent number: 6825230Abstract: A means and method for treating malaria, schistosomiasis, and cancer using a spiro or dispiro 1,2,4-trioxolane is described. The preferred 1,2,4-trioxolanes include a spiroadamantane group on one side of the trioxolane group, and a spirocyclohexyl on the other side of the trioxolane group, whereby the spirocyclohexyl ring is preferably substituted at the 4-position. In comparison to artemisinin semisynthetic derivatives, the compounds of this invention are structurally simple, easy to synthesize, non-toxic, and potent against malarial parasites.Type: GrantFiled: August 18, 2003Date of Patent: November 30, 2004Assignee: Medicines for Malaria Venture MMVInventors: Jonathan L. Vennerstrom, Yuxiang Dong, Jacques Chollet, Hugues Matile, Maniyan Padmanilayam, Yuanqing Tang, William N. Charman
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Publication number: 20040186168Abstract: A means and method for treating malaria, schistosomiasis, and cancer using a spiro or dispiro 1,2,4-trioxolane is described. The preferred 1,2,4-trioxolanes include a spiroadamantane group on one side of the trioxolane group, and a spirocyclohexyl on the other side of the trioxolane group, whereby the spirocyclohexyl ring is preferably substituted at the 4-position. In comparison to artemisinin semisynthetic derivatives, the compounds of this invention are structurally simple, easy to synthesize, non-toxic, and potent against malarial parasites.Type: ApplicationFiled: December 19, 2003Publication date: September 23, 2004Applicant: MEDICINES FOR MALARIA VENTURE MMVInventors: Jonathan L. Vennerstrom, Yuxiang Dong, Jacques Chollet, Hugues Matile, Maniyan Padmanilayam, Yuangqing Tang, William N. Charman
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Publication number: 20040039008Abstract: A means and method for treating malaria, schistosomiasis, and cancer using a spiro or dispiro 1,2,4-trioxolane is described. The preferred 1,2,4-trioxolanes include a spiroadamantane group on one side of the trioxolane group, and a spirocyclohexyl on the other side of the trioxolane group, whereby the spirocyclohexyl ring is preferably substituted at the 4-position. In comparison to artemisinin semisynthetic derivatives, the compounds of this invention are structurally simple, easy to synthesize, non-toxic, and potent against malarial parasites.Type: ApplicationFiled: August 18, 2003Publication date: February 26, 2004Applicant: Medicines for Malaria Ventures MMVInventors: Jonathan L. Vennerstrom, Yuxiang Dong, Jacques Chollet, Hugues Matile, Maniyan Padmanilayam, Yuanqing Tang, William N. Charman
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Patent number: 6486199Abstract: A means and method for treating malaria using a spiro or dispiro 1,2,4-trioxolane is described. The preferred 1,2,4-trioxolanes include a spiroadamantane group on one side of the trioxolane group, and a spirocyclohexyl or spiropiperidyl ring on the other side of the trioxolane group, whereby the spirocyclohexyl ring is preferably functionalized or substituted at the 4-position or a spiropiperidyl ring that is functionalized or substituted at the nitrogen atom. In comparison to artemisinin semisynthetic derivatives, the compounds of this invention are structurally simple, easy to synthesize, non-toxic, and potent against malarial parasites.Type: GrantFiled: June 21, 2001Date of Patent: November 26, 2002Assignee: Medicines for Malaria Venture MMV International Centre CointrinInventors: Jonathan L. Vennerstrom, Yuxiang Dong, Jacques Chollet, Hugues Matile