Abstract: Compositions and methods for binding to target antigens. Compositions comprising variable heavy chain domains with binding specificity to CD70, GPC3, IL13Ralpha2 and Cadherin CDH17 antigens.

Abstract: The present disclosure provides compositions and methods for making and using engineered killer phagocytic cells for immunotherapy in cancer or infection by expressing a chimeric antigen receptor having an enhanced phagocytic activity, the chimeric receptor is encoded by a recombinant nucleic acid.

Abstract: Compositions and methods for making and using engineered cells, such as, engineered myeloid cells that express a chimeric fusion protein that has a binding domain capable to binding surface molecules on target cells such as diseased cells.

Abstract: Compositions and methods for making and using therapeutic agents comprising myeloid cell specific engagers, used for immunotherapy of cancer or infection.

Abstract: Compositions and methods for making and using engineered cells, such as, engineered myeloid cells that express a chimeric fusion protein that has a binding domain capable to binding surface molecules on target cells such as diseased cells.

Abstract: Compositions and methods for making and using engineered cells, such as, engineered myeloid cells that express a chimeric fusion protein that has a binding domain capable to binding surface molecules on target cells such as diseased cells.

Abstract: Compositions and methods for making and using engineered myeloid cells that express a chimeric fusion protein for immunotherapy and compositions and methods for making and using engineered T cells that express a chimeric antigen receptor for immunotherapy.

Abstract: Embodiments of the present disclosure provide a multimedia object sharing method, an electronic device, and a storage medium, wherein the method includes: displaying a multimedia list creation page, in response to a trigger operation for multimedia list creation, to edit associated content corresponding to a multimedia list to be shared in the multimedia list creation page; displaying an information editing page to determine a target sharing user and a target shared object in the multimedia list to be shared based on a trigger operation on the information editing page; and sharing the multimedia list to be shared to the target sharing user.

Abstract: The embodiment of the disclosure provides an interaction method based on multimedia objects, device, electronic apparatus and a storage medium. The method includes: displaying user identification information of at least one target user in a display interface; the target user is a user who posts a target multimedia object; determining a display mode of a target multimedia object corresponding to a triggered user identification information based on a triggering operation on the user identification information and a posting state of a current user; and displaying the target multimedia object based on the display mode.

Abstract: The present disclosure provides compositions and methods for making and using engineered myeloid cells for immunotherapy in cancer or infection by expressing a chimeric antigen receptor having an enhanced phagocytic activity, wherein the chimeric receptor is encoded by a recombinant nucleic acid.

Abstract: Compositions and methods for making and using engineered cells, such as, engineered myeloid cells that express a chimeric fusion protein that has a binding domain capable to binding surface molecules on target cells such as diseased cells.

Abstract: An aspect of the present invention is provided with a sensitive data protection code generating unit which generates a sensitive data protection code of a predetermined data length, a symmetric encryption key generating unit which generates a symmetric encryption key by using a key derivation function that takes, as input, the sensitive data protection code, a sensitive data encrypting unit which encrypts sensitive data by using the symmetric encryption key, a sensitive data protection code encrypting unit which encrypts the sensitive data protection code by using a public key provided from an sensitive data access support terminal, and a deleting unit which deletes the symmetric encryption key and the sensitive data after the encryption of the sensitive data, and deletes the sensitive data protection code after the encryption of the sensitive data protection code.

Abstract: Compositions and methods for making and using engineered phagocytic cells that express a chimeric antigen receptor having an enhanced phagocytic activity for stable and durable expression are described and can be suitably used for immunotherapy in cancer or infection.

Abstract: Methods and composition for modulating a target genome and stable integration of a transgene of interest into the genome of a cell are disclosed.

Abstract: Methods and composition for modulating a target genome and stable integration of a transgene of interest into the genome of a cell are disclosed.

Abstract: Compositions and methods for making and using engineered cells, such as, engineered myeloid cells that express a chimeric fusion protein that has a binding domain capable to binding surface molecules on target cells such as diseased cells.

Abstract: Compositions and methods for making and using engineered cells, such as, engineered myeloid cells that express a chimeric fusion protein that has a binding domain capable to binding surface molecules on target cells such as diseased cells.

Abstract: A routing information transmission method includes before forwarding a service traffic packet, a first network device receives first Border Gateway Protocol (BGP) routing information from a second network device to determine a first forwarding table entry based on a service identifier and an identifier of a first network slice that are in the first BGP routing information. The first forwarding table entry indicates to forward, to the second network device using the first network slice, the service traffic. When receiving the service traffic packet corresponding to the service identifier, the first network device determines the first network slice based on the first forwarding table entry, and then sends the service traffic to the second network device using the first network slice.

Abstract: Methods and composition for modulating a target genome and stable integration of a transgene of interest into the genome of a cell are disclosed.