Abstract: Provided are a quinazoline derivative, a pharmaceutical composition containing the same, a method for preparation of said derivative, and an application of same as an anti-cancer drug.

Abstract: Provided are a quinazoline derivative, a pharmaceutical composition containing the same, a method for preparation of said derivative, and an application of same as an anti-cancer drug.

Abstract: A kit for securing cargo within an interior of a vehicle is provided. The vehicle has an occupant restraint system including a coupling member. The kit includes a harness having at least one connecting ring. The harness is configured to hold the cargo. The kit includes a first strap having a first connector at a first end releasably coupled to the coupling member and a second connector at a second end coupled to the at least one connecting ring. The kit includes an energy absorbing element defined on the strap between the first end and the second end. The energy absorbing element is deformable to absorb a force acting on the cargo.

Abstract: The present invention relates to ?-carboline, dihydro-?-carboline and tetrahydro-?-carboline alkaloid derivatives (I) and a method for preparing same and the use in the aspects of preventing and treating plant viruses, fungicides and insecticides. For the meaning of each group in formula (I) see the description. The ?-carboline, dihydro-?-carboline and tetrahydro-?-carboline alkaloid derivatives of the present invention show a particularly ourstanding anti-plant virus activity, and also have fungicidal and insecticidal activities.

Abstract: A kit for securing cargo within an interior of a vehicle is provided. The vehicle has an occupant restraint system including a coupling member. The kit includes a harness having at least one connecting ring. The harness is configured to hold the cargo. The kit includes a first strap having a first connector at a first end releasably coupled to the coupling member and a second connector at a second end coupled to the at least one connecting ring. The kit includes an energy absorbing element defined on the strap between the first end and the second end. The energy absorbing element is deformable to absorb a force acting on the cargo.

Abstract: The present invention relates to a benzamide derivative of general formula I, a drug composition containing same and a use thereof as a drug, wherein the definitions of R1, Z and Q are as described in the description.

Abstract: A novel nucleoside phosphoramidate compound of the formula below, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection, and having a good anti-HCV effect; a pharmaceutical composition having the compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof:

Abstract: The present invention relates to the petroleum drilling fluid field, and discloses a modified silicon dioxide nano-particle comprising a modifying polymer chain composed of structural units provided by one or more of monomers represented by the following formula (1) and one or more of monomers represented by the following formula (2). The present invention provides a method for preparing modified silicon dioxide nano-particles and a drilling fluid suitable for shale gas wells containing the modified silicon dioxide nano-particles as a plugging agent. When the modified silicon dioxide nano-particles provided in the present invention are used as a plugging agent in a drilling fluid, they will not agglomerate into large-size particles, and can achieve a good plugging effect.

Abstract: Provided are a quinazoline derivative, a pharmaceutical composition containing the same, a method for preparation of said derivative, and an application of same as an anti-cancer drug.

Abstract: A liquid titanium-based catalyst and method for preparing polyester polymer thereof are disclosed herein. The catalyst is made by tetrabutyl titanate, 1-4 butanediol, phosphate ester, hydroxycarboxylic acid, TEOS, acetates of metal element through heating reactions in an appropriate amount of solvent. While the catalyst maintains a high activity, the synthetic slices have good hue, with high molecular weight, stable property, resistance to hydrolysis, moreover, the catalyst is a stable multicomponent liquid catalyst based on titanium, silicon. It can be directly added or diluted to add to the raw material ester or oligoester to be poly-condensed used for synthesis of polyesters which can be used in the production of fibers, engineering plastics, films, PET bottles, sheets and profiles, etc.

Abstract: The present invention relates to ?-carboline, dihydro-?-carboline and tetrahydro-?-carboline alkaloid derivatives (I) and a method for preparing same and the use in the aspects of preventing and treating plant viruses, fungicides and insecticides. For the meaning of each group in formula (I) see the description. The ?-carboline, dihydro-?-carboline and tetrahydro-?-carboline alkaloid derivatives of the present invention show a particularly ourstanding anti-plant virus activity, and also have fungicidal and insecticidal activities.

Abstract: The present subject matter discloses a reservoir protecting agent composition, consisting of non-fluorescent sulfonated asphalt and a reservoir protecting agent, wherein, the reservoir protecting agent is composed of structural units denoted by the following formula (1), (2), and (3). The present subject matter further provides a drilling fluid that contains the above-mentioned reservoir protecting agent composition for middle permeability reservoirs. The present subject matter further provides an application of the drilling fluid for middle permeability reservoirs in well drilling in middle permeability reservoirs. The drilling fluid for middle permeability reservoirs disclosed in the present subject matter exhibits favorable rheology property, temperature tolerance property, and anti-collapse and protection performance when it is used in wall drilling in middle permeability reservoirs.

Abstract: The present subject matter relates to a preparation method of a wettability reversal agent, comprising: (1) adding an emulsifier into water to prepare a mixed solution of emulsifier; (2) adding compounds represented by formula (1-a), (2-a), (3-a), (4-a), (5-a), and (6-a) to the mixed solution of emulsifier to obtain a pre-emulsion, adding an initiator, and initiating a polymerization reaction. When the wettability reversal agent and reservoir protecting agent composition disclosed in the present subject matter are used in a drilling fluid, they can effectively prevent the permeation of the water phase and oil phase in the drilling fluid into the reservoir, reduce the filter loss of the drilling fluid, and thereby effectively protect the reservoir against damages from the drilling fluid.

Abstract: The present subject matter relates to a reservoir protecting agent composition, consisting of non-fluorescent sulfonated asphalt, micron-sized cellulose, and a reservoir protecting agent, wherein, the reservoir protecting agent is composed of structural units denoted by the following formula (1), formula (2), and formula (3). The present subject matter further provides a broad-spectrum drilling fluid that contains the reservoir protecting agent composition. The present subject matter further provides a use of the broad-spectrum drilling fluid in oil and gas well drilling. When the broad-spectrum drilling fluid provided in the present subject matter is used in oil and gas well drilling in reservoirs with different structures, it exhibits good rheology property, temperature tolerance, and anti-collapse and protection performance.

Abstract: The present subject matter relates to a protecting agent composition for high/ultra-high permeability reservoirs, consisting of a protecting agent and a filler, wherein, the filler comprises calcium carbonate of 600-1,000 mesh, calcium carbonate of 300-590 mesh, and calcium carbonate of 50-200 mesh at 1:(1-30):(0-40) weight ratio, and the protecting agent comprises structural units denoted by the following formulae (1), (2), and (3). The present subject matter further provides a drilling fluid containing the above-mentioned composition. The present subject matter further provides a use of the drilling fluid for drilling in high/ultra-high permeability reservoirs. The drilling fluid provided in the present subject matter has advantages including easy use, high environmental friendliness, and outstanding reservoir protection, greatly reduces the damages of drilling fluid to high/ultra-high permeability reservoirs, and brings substantial economic benefits.

Abstract: A novel nucleoside phosphoramidate compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection is provided. The pharmaceutical composition having the compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof and a use of the compound or the composition in the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection. The compound has a good anti-HCV effect.

Abstract: Provided is a crystalline form E of ertapenem sodium. Further provided is a method for preparing a crystalline form E of ertapenem sodium, characterized by using an aqueous ertapenem sodium solution at a low concentration as a raw material. The crystalline form E can be easily filtered and dried, the properties in the drying process are stable, and the purity of the crystal is high and can be up to 98.5% or higher.

Abstract: Provided is a crystalline form E of ertapenem sodium. Further provided is a method for preparing a crystalline form E of ertapenem sodium, characterized by using an aqueous ertapenem sodium solution at a low concentration as a raw material. The crystalline form E can be easily filtered and dried, the properties in the drying process are stable, and the purity of the crystal is high and can be up to 98.5% or higher.

Abstract: Disclosed are a catalyst suitable for the conversion of carbon monoxide with steam into carbon dioxide and hydrogen, and a process therewith for said conversion. Said catalyst comprises Co, Ni, Mo and/or W active components, TiO.sub.2 -containing carrier and non-alkali metal element promoter(s). Said process comprises reacting carbon monoxide feed gas containing 0.01% or more of H.sub.2 S by volume with steam in the presence of said catalyst at a temperature between 230 to 500.degree. C. under a pressure between 0 to 10 MPa (absolute) with a relatively high yield, whereby heavy fuel can be used as a source of carbon monoxide feed gas for such a process.