Patents by Inventor Yuxiu Ma

Yuxiu Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230144619
    Abstract: Provided in the present invention are a salt of an arylaminopurine derivative represented by Formula (2), a preparation method therefor and the use thereof. The salt obtained in the present invention has good crystallinity and significantly improved solubility relative to that in the free form, and the preferred salt and crystal form have low hygroscopicity and can exist stably. Therefore, compared with the free form of arylaminopurine derivatives or other salts, it is easier to prepare same into a medicine.
    Type: Application
    Filed: January 22, 2021
    Publication date: May 11, 2023
    Applicant: CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd.
    Inventors: Dehua Ji, Shengyong Yang, Xiaofeng Guo, Chen Zhang, Linli Li, Yuxiu Ma, Xiaowei Sun, Qiaoli Cui, Feng Guo, Haohao Zhang
  • Publication number: 20230144023
    Abstract: The present application provides application of butylphthalide or optical isomer, prodrug, deuterium, metabolite, and ring-opening product or ring-opening product salt thereof in the preparation of a drug for preventing, alleviating, or treating peripheral neuropathy, especially chemotherapy-induced peripheral neuropathy, and a use method of butylphthalide and a derivative thereof in preventing or treating peripheral neuropathy, especially chemotherapy-induced peripheral neuropathy. In vivo and in vitro studies show that the drug of the present invention can effectively prevent, alleviate, or treat peripheral neuropathy caused by chemotherapy drugs without affecting the tumor-inhibiting efficacy and pharmacokinetic properties of the chemotherapy drugs.
    Type: Application
    Filed: March 19, 2021
    Publication date: May 11, 2023
    Inventors: Xibao LIU, Yanling LI, Jieru LIU, Stuart C. APFEL, Yuxiu MA, Xiaojuan WU, Yuqing WANG, Hanyu YANG
  • Patent number: 10774079
    Abstract: Provided are a quinazoline derivative, a pharmaceutical composition containing the same, a method for preparation of said derivative, and an application of same as an anti-cancer drug.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: September 15, 2020
    Assignee: CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD.
    Inventors: Ying Shi, Qingzhi Gao, Xiaozhuo Chen, Yi Mi, Yaran Zhang, Hanyu Yang, Yujie Chen, Chunlei Liu, Guorui Mi, Yuxiu Ma, Dongmin Shen, Yang Guo, Linjing Fan
  • Patent number: 10550073
    Abstract: The present invention relates to a benzamide derivative of general formula I, a drug composition containing same and a use thereof as a drug, wherein the definitions of R1, Z and Q are as described in the description.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: February 4, 2020
    Assignee: CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd.
    Inventors: Ying Shi, Yi Mi, Hanyu Yang, Xuliang Wang, Denghuang Gong, Min Bai, Xiaozhuo Chen, Yujie Chen, Xuejiao Zhang, Yuxiu Ma, Qingzhi Gao
  • Publication number: 20190367500
    Abstract: Provided are a quinazoline derivative, a pharmaceutical composition containing the same, a method for preparation of said derivative, and an application of same as an anti-cancer drug.
    Type: Application
    Filed: August 8, 2019
    Publication date: December 5, 2019
    Inventors: Ying SHI, Qingzhi GAO, Xiaozhuo CHEN, Yi MI, Yaran ZHANG, Hanyu YANG, Yujie CHEN, Chunlei LIU, Guorui MI, Yuxiu MA, Dongmin SHEN, Yang GUO, Linjing FAN
  • Patent number: 10421754
    Abstract: Provided are a quinazoline derivative, a pharmaceutical composition containing the same, a method for preparation of said derivative, and an application of same as an anti-cancer drug.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: September 24, 2019
    Assignee: CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD.
    Inventors: Ying Shi, Qingzhi Gao, Xiaozhuo Chen, Yi Mi, Yaran Zhang, Hanyu Yang, Yujie Chen, Chunlei Liu, Guorui Mi, Yuxiu Ma, Dongmin Shen, Yang Guo, Linjing Fan
  • Publication number: 20180312462
    Abstract: The present invention relates to a benzamide derivative of general formula I, a drug composition containing same and a use thereof as a drug, wherein the definitions of R1, Z and Q are as described in the description.
    Type: Application
    Filed: September 30, 2016
    Publication date: November 1, 2018
    Inventors: Ying SHI, Yi MI, Hanyu YANG, Xuliang WANG, Denghuang GONG, Min BAI, Xiaozhuo CHEN, Yujie CHEN, Xuejiao ZHANG, Yuxiu MA, Qingzhi GAO
  • Publication number: 20170226099
    Abstract: Provided are a quinazoline derivative, a pharmaceutical composition containing the same, a method for preparation of said derivative, and an application of same as an anti-cancer drug.
    Type: Application
    Filed: August 11, 2015
    Publication date: August 10, 2017
    Inventors: Ying SHI, Qingzhi GAO, Xiaozhuo CHEN, Yi MI, Yaran ZHANG, Hanyu YANG, Yujie CHEN, Chunlei LIU, Guorui MI, Yuxiu MA, Dongmin SHEN, Yang GUO, Linjing FAN
  • Patent number: 9012628
    Abstract: Provided is a crystalline form E of ertapenem sodium. Further provided is a method for preparing a crystalline form E of ertapenem sodium, characterized by using an aqueous ertapenem sodium solution at a low concentration as a raw material. The crystalline form E can be easily filtered and dried, the properties in the drying process are stable, and the purity of the crystal is high and can be up to 98.5% or higher.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: April 21, 2015
    Assignee: CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co. Ltd.
    Inventors: Ying Shi, Kun Li, Xuebin Zhao, Zan Xie, Yuxiu Ma, Jian Lv, Ming Jia
  • Publication number: 20130281427
    Abstract: Provided is a crystalline form E of ertapenem sodium. Further provided is a method for preparing a crystalline form E of ertapenem sodium, characterized by using an aqueous ertapenem sodium solution at a low concentration as a raw material. The crystalline form E can be easily filtered and dried, the properties in the drying process are stable, and the purity of the crystal is high and can be up to 98.5% or higher.
    Type: Application
    Filed: December 22, 2011
    Publication date: October 24, 2013
    Applicant: CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd.
    Inventors: Ying Shi, Kun Li, Xuebin Zhao, Zan Xie, Yuxiu Ma, Jian Lv, Ming Jia