Abstract: Provided herein are genetically engineered Pichinde viruses that include three ambiense genomic segments. The first genomic segment includes two coding regions encoding a Z protein and a L RdRp protein. The second genomic segment includes a coding region encoding a nucleoprotein (NP) and the third genomic segment includes a coding region encoding a glycoprotein. Each of the second and third genomic segments include an additional coding region that may encode a reovirus sigma C protein or a reovims sigma B protein. In one embodiment, a genetically engineered Pichinde virus encodes a reovims sigma C protein and a reovirus sigma B protein. Also provided herein is a reverse genetics system for making genetically engineered Pichinde virus, and a collection of vectors that can be used to produce genetically engineered Pichinde virus. Further provided are methods for using a reverse genetics system, and methods for treating a reovirus infection in a subject.

Abstract: In a method for sending a server identifier to a KVM switch, a management processor of a server determines that a push button on an exterior surface of the server has been pushed. In response to determining that the push button has been pushed, the management processor generates a displayable image containing a server identifier for the server, includes the displayable image in a network message, and broadcasts the network message to a local network that includes the server and a KVM switch. In one example, the method also includes receiving the server button message at the KVM switch when the KVM switch is not switched to enable the server to control a video port of the KVM switch, and in response to receiving the server button message at the KVM switch, sending the displayable image to a monitor via the video port. Other implementations are described and claimed.

Abstract: In a method for sending a server identifier to a KVM switch, a management processor of a server determines that a push button on an exterior surface of the server has been pushed. In response to determining that the push button has been pushed, the management processor generates a displayable image containing a server identifier for the server, includes the displayable image in a network message, and broadcasts the network message to a local network that includes the server and a KVM switch. In one example, the method also includes receiving the server button message at the KVM switch when the KVM switch is not switched to enable the server to control a video port of the KVM switch, and in response to receiving the server button message at the KVM switch, sending the displayable image to a monitor via the video port. Other implementations are described and claimed.

Abstract: Provided herein is a SARS-CoV-2 coronavirus nucleocapsid (N) protein, where the N protein is substantially free of RNA. Also provided are methods of using the N protein including methods for inducing anti-N protein antibody in a subject, treating an infection, and detecting the presence or absence of anti-N protein antibody.

Abstract: Systems and methods described herein provide tactile challenge-response tests for limiting access to electronic resources associated with a computing system. When a user requests access an electronic resource, the system activates an alternating voltage in an electrode layer for a display associated with the system to generate an electrovibrational pattern on the display and prompting the user to perform a touch gesture upon the affected region of the display to allow the user to perceive the electrovibrational pattern via the user's sense of touch. Next, the computing system renders multiple different visual patterns on the display and prompts the user to select the visual pattern that matches the electrovibrational pattern. If the user correctly selects the visual pattern that matches the electrovibrational pattern, the system allows the user to access the electronic resource.

Abstract: Provided herein are genetically engineered Pichinde viruses that include three ambisense genomic segments. The first genomic segment includes a coding region encoding a Z protein and a coding region encoding a L RdRp protein. The second genomic segment includes a coding region encoding a nucleoprotein (NP) and the third genomic segment includes a coding region encoding a glycoprotein. Each of the second and third genomic segments optionally include an additional coding region that may encode an antigen or a detectable marker. Also provided herein is a reverse genetics system for making a genetically engineered Pichinde virus, and a collection of vectors that can be used to produce a genetically engineered Pichinde virus. Further provided are methods for using a reverse genetics system, and methods for producing an immune response in a subject.

Abstract: Systems and methods described herein provide tactile challenge-response tests for limiting access to electronic resources associated with a computing system. receiving, When a user requests access an electronic resource, the system activates an alternating voltage in an electrode layer for a display associated with the system to generate an electrovibrational pattern on the display and prompting the user to perform a touch gesture upon the affected region of the display to allow the user to perceive the electrovibrational pattern via the user's sense of touch. Next, the computing system renders multiple different visual patterns on the display and prompts the user to select the visual pattern that matches the electrovibrational pattern. If the user correctly selects the visual pattern that matches the electrovibrational pattern, the system allows the user to access the electronic resource.

Abstract: Provided herein are genetically engineered Pichinde viruses that include three ambisense genomic segments. The first genomic segment includes a coding region encoding a Z protein and a coding region encoding a L RdRp protein. The second genomic segment includes a coding region encoding a nucleoprotein (NP) and the third genomic segment includes a coding region encoding a glycoprotein. Each of the second and third genomic segments optionally include an additional coding region that may encode an antigen or a detectable marker. Also provided herein is a reverse genetics system for making a genetically engineered Pichinde virus, and a collection of vectors that can be used to produce a genetically engineered Pichinde virus. Further provided are methods for using a reverse genetics system, and methods for producing an immune response in a subject.

Abstract: Provided herein are genetically engineered Pichinde viruses that include three ambisense genomic segments. The first genomic segment includes a coding region encoding a Z protein and a coding region encoding a L RdRp protein. The second genomic segment includes a coding region encoding a nucleoprotein (NP) and the third genomic segment includes a coding region encoding a glycoprotein. Each of the second and third genomic segments optionally include an additional coding region that may encode an antigen or a detectable marker. Also provided herein is a reverse genetics system for making a genetically engineered Pichinde virus, and a collection of vectors that can be used to produce a genetically engineered Pichinde virus. Further provided are methods for using a reverse genetics system, and methods for producing an immune response in a subject.