Patents by Inventor Yuying Zhang
Yuying Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250120412Abstract: Provided are a multi-layer fermentation tank for tea leaves and a use method thereof. The multi-layer fermentation tank for tea leaves includes a tank body, a placement assembly, a heater, and an oxygen supply machine. The placement assembly includes a support frame, and a tray. The support frame includes a turnover plate, laminate groups located at upper and lower sides of the turnover plate, and a top cover located above the laminate group at the upper side. A telescopic connection mechanism is arranged among the turnover plate, the laminate and the top cover, an upper surface of each of the turnover plate and the laminate is provided with a placement groove, the tray is placed in the placement groove, and a positioning member is arranged between the tray and the placement groove. Gas holes are formed in each of the turnover plate, the laminate, the tray, and the top cover.Type: ApplicationFiled: October 10, 2024Publication date: April 17, 2025Inventors: Xiaoli LI, Yong HE, Qinghai HE, Xuelun LUO, Yuying ZHANG, Huahao YU
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Publication number: 20250000819Abstract: The present disclosure provides an anti-hypoxic/anoxic injury use of a magnolol and/or honokiol aromatic ring amino-substituted derivative, and a pharmaceutical composition. The derivative is a compound represented by general formula I or a salt thereof: wherein, R1 and R4 are each independently selected from a C1-C8 hydrocarbyl, R2 and R3 are each independently selected from hydrogen or hydroxyl, and R2 and R3 are not both the hydrogen or hydroxyl; R5 is selected from any one of H, a C1-C12 acyl, a remaining acyl moiety of a single amino acid after condensation of its carboxyl, or a remaining acyl moiety of a polypeptide after condensation of its carboxyl; and R6 is selected from any one of hydrogen or C1-C8 hydrocarbyl. The derivative of the structure shown in general formula I may be solved problems of indirect onset and slow onset and the like of existing anti-hypoxic/anoxic drugs.Type: ApplicationFiled: October 27, 2022Publication date: January 2, 2025Inventors: Pingping ZHANG, Ye LIU, Yuying ZHANG
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Patent number: 12147440Abstract: Techniques are provided for gathering statistics in a database system. The techniques involve gathering some statistics using an “on-the-fly” technique, some statistics through a “high-frequency” technique, and yet other statistics using a “prediction” technique. The technique used to gather each statistic is based, at least in part, on the overhead required to gather the statistic. For example, low-overhead statistics may be gathered “on-the-fly” using the same process that is performing the operation that affects the statistic, while statistics whose gathering incurs greater overhead may be gathered in the background, while the database is live, using the high-frequency technique. The prediction technique may be used for relatively-high overhead statistics that can be predicted based on historical data and the current value of predictor statistics.Type: GrantFiled: September 23, 2021Date of Patent: November 19, 2024Assignee: Oracle International CorporationInventors: Mohamed Zait, Yuying Zhang, Hong Su, Jiakun Li
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Publication number: 20240360459Abstract: The present disclosure provides a Mycobacterium tuberculosis (Mtb) adenosine triphosphate (ATP) synthase-expressing recombinant bacterium, and a construction method and an expression method thereof, and belongs to the technical field of exogenous expression. The present disclosure provides a construction method of an Mtb ATP synthase-expressing recombinant bacterium, including the following steps: using a Mycobacterium smegmatis (Msm) competent cell containing an auxiliary gene knockout plasmid as a basal cell; transferring an Mtb ATP synthase gene cluster with an affinity purification tag into the basal cell, knocking out a Msm ATP synthase genome, and collecting a strain without the auxiliary gene knockout plasmid after conducting repeated subculture; and transferring the Mtb ATP synthase gene cluster into the strain by prokaryotic expression to obtain the Mtb ATP synthase-expressing recombinant bacterium.Type: ApplicationFiled: February 9, 2024Publication date: October 31, 2024Inventors: Hongri Gong, Yuying Zhang, Zihe Rao
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Publication number: 20240139208Abstract: The present disclosure relates to a combined pharmaceutical composition containing a CDK4/6 inhibitor and a use thereof, and specifically relates to a combined pharmaceutical composition comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof and fulvestrant. The present disclosure further relates to a use of the combined pharmaceutical composition in treating breast cancer. The combined pharmaceutical composition of the present disclosure produces better therapeutic effects in reducing tumor growth or even eliminating tumors.Type: ApplicationFiled: March 3, 2022Publication date: May 2, 2024Inventors: Fan FENG, Ding YU, Xungiang WANG, Xiquan ZHANG, Yanfeng BAI, Chaoqiang YANG, Yuying ZHANG
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Patent number: 11965821Abstract: An optical fiber sensing system for temperature and salinity synchronous measurement is provided, which includes a broad-spectrum light source, an optical fiber circulator, a coupler, a first interferometer, a second interferometer, a third interferometer and a spectrometer; the first interferometer is insensitive to temperature and salinity; the second interferometer is sensitive to both temperature and salinity, and the third interferometer is only sensitive to temperature; light emitted by the broad-spectrum light source passes through the optical fiber circulator and enters the first interferometer; reflected light of the first interferometer passes through the optical fiber circulator and the coupler sequentially, and then enters the second and the third interferometers respectively; the reflected light of the second and the third interferometers enters the spectrometer after passing through the coupler; the temperature and the salinity to be measured are simultaneously obtained by performing spectral anType: GrantFiled: August 26, 2023Date of Patent: April 23, 2024Assignee: Guangdong Ocean UniversityInventors: Xiaoguang Mu, Lin Sun, Yuying Zhang, Yuting Li, Kun Song, Jiale Gao, Yuqiang Yang
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Publication number: 20240034763Abstract: The present disclosure provides conjugates of polypeptides comprising nanobody and FGF21 linked by a polypeptide linker. The present disclosure further provides conjugates of polypeptides comprising GLP-1, nanobody, and FGF21 linked by two polypeptide linkers respectively. Pharmaceutical compositions comprising the same and methods of treating diseases are also provided.Type: ApplicationFiled: June 5, 2023Publication date: February 1, 2024Inventors: Yuanyuan ZHANG, Bo WU, Wei GUO, Xiaona DONG, Yuying ZHANG
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Publication number: 20230411608Abstract: Provided are ternary positive electrode material precursor and preparation method thereof, positive electrode material, positive electrode slurry, lithium-ion battery, positive electrode thereof, and electrical equipment. The ternary positive electrode material precursor includes core layer, intermediate layer, and shell layer, wherein the porosities of the core layer, the intermediate layer, and the shell layer increase sequentially. The preparation method is mixing raw materials including nickel source, cobalt source, manganese source, a precipitating agent, and a complexing agent; and performing reaction of solution coprecipitation method. The positive electrode material is made of raw materials including the ternary positive electrode material precursor. The positive electrode slurry is made of raw materials including the positive electrode material. The lithium-ion battery positive electrode is made of raw materials including the positive electrode slurry.Type: ApplicationFiled: September 1, 2023Publication date: December 21, 2023Inventors: Shuo Yin, Yuying Zhang, Fangli Ji, Yiqiao Wang
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Publication number: 20230401665Abstract: A machine vision functionality deployment system for transcoding a raw machine vision data signal in an existing machine vision system for capturing sensed information from a substrate. Provided is a digital data interface bus to: receive raw machine vision digital data signals from an acquisition device. The raw machine vision digital data signals are in an acquisition device format and to output a transcoded machine vision digital data signal to a consumption device in a consumption device format. A digital data processor in communication to the digital data interface bus operable to: identify digital data elements associated with an artifact of the substrate in the raw machine vision digital data signal, wherein the artifact is not detectable by the consumption device; transcode the raw machine vision digital data signal by rendering the artifact detectable in the transcoded machine vision digital data signal by the consumption device.Type: ApplicationFiled: November 9, 2021Publication date: December 14, 2023Inventors: Chris Eric Warkentin, Jonathan Chapman Hou, Glenn Andrew Varsava, Zachary Jeremy O'Beirn, Yuying Zhang
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Patent number: 11468073Abstract: Techniques are provided for gathering statistics in a database system. The techniques involve gathering some statistics using an “on-the-fly” technique, some statistics through a “high-frequency” technique, and yet other statistics using a “prediction” technique. The technique used to gather each statistic is based, at least in part, on the overhead required to gather the statistic. For example, low-overhead statistics may be gathered “on-the-fly” using the same process that is performing the operation that affects the statistic, while statistics whose gathering incurs greater overhead may be gathered in the background, while the database is live, using the high-frequency technique. The prediction technique may be used for relatively-high overhead statistics that can be predicted based on historical data and the current value of predictor statistics.Type: GrantFiled: August 6, 2019Date of Patent: October 11, 2022Assignee: Oracle International CorporationInventors: Mohamed Zait, Yuying Zhang, Hong Su, Jiakun Li
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Patent number: 11427773Abstract: Disclosed is a catalytic cracking process for producing isobutane and/or light aromatics in high yield, comprising the steps of: a) providing a catalytic cracking feedstock oil having a polycyclic naphthene content of greater than about 25 wt %; b) subjecting the catalytic cracking feedstock oil to a first catalytic cracking reaction and a second catalytic cracking reaction sequentially under different reaction conditions to obtain a catalytic cracking product; c) separating the resulting catalytic cracking product to obtain a liquefied gas fraction comprising isobutane and a gasoline fraction comprising light aromatics; and d) optionally, recovering isobutane from the liquefied gas fraction and/or recovering light aromatics from the gasoline fraction. The process can enable the production of isobutane and/or light aromatics in high yield.Type: GrantFiled: October 22, 2018Date of Patent: August 30, 2022Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPECInventors: Youhao Xu, Xin Wang, Yuying Zhang, Tao Liu, Xuhui Bai, Lishun Dai, Zhigang Zhang, Jialin Liang, Nan Jiang
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Publication number: 20220012240Abstract: Techniques are provided for gathering statistics in a database system. The techniques involve gathering some statistics using an “on-the-fly” technique, some statistics through a “high-frequency” technique, and yet other statistics using a “prediction” technique. The technique used to gather each statistic is based, at least in part, on the overhead required to gather the statistic. For example, low-overhead statistics may be gathered “on-the-fly” using the same process that is performing the operation that affects the statistic, while statistics whose gathering incurs greater overhead may be gathered in the background, while the database is live, using the high-frequency technique. The prediction technique may be used for relatively-high overhead statistics that can be predicted based on historical data and the current value of predictor statistics.Type: ApplicationFiled: September 23, 2021Publication date: January 13, 2022Inventors: Mohamed Zait, Yuying Zhang, Hong Su, Jiakun Li
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Patent number: 11058716Abstract: Provided are a method, target and application for NO accumulation to decrease invasiveness of Pseudomonas aeruginosa; achieving NO accumulation by means of external NO donors or disruption of internal NO metabolism in an environment where Pseudomonas aeruginosa is growing or being cultured, in order to decrease production by Pseudomonas aeruginosa of the invasion factor pyocyanin. Utilizing even micro-quantities of NO can significantly inhibit Pseudomonas aeruginosa PCN (PCN synthesis down 82% with 60 ?M SNP treatment); by inhibiting NO reductase, an enzyme related to NO metabolism, PCN synthesis can be significantly inhibited (the PAO1-?nor strain has 84% PCN reduction). Using NO donors or inhibiting enzymes involved in Pseudomonas aeruginosa NO metabolism as a means of combating bacterial infectious disease does not affect the body's normal microflora like traditional antibiotics.Type: GrantFiled: January 9, 2020Date of Patent: July 13, 2021Inventors: Yi Wan, Chang Chen, Lei Gao, Yuying Zhang, Xinhua Qiao, Yan Wang
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Patent number: 10961471Abstract: A process for producing catalytic cracking gasoline includes the following steps: i) subjecting a heavy feedstock oil to a catalytic cracking reaction in the presence of a first catalytic cracking catalyst to obtain a first reaction product; ii) subjecting a hydrogenated cycle oil to a catalytic cracking reaction in the presence of a second catalytic cracking catalyst to obtain a second reaction product; iii) separating a mixture of the first reaction product and the second reaction product to obtain a catalytic cracking gasoline and a catalytic cracking light cycle oil; iv) subjecting the catalytic cracking light cycle oil or a fraction thereof to hydrogenation to obtain a hydrogenated product; and v) recycling the hydrogenated product to the step ii) as the hydrogenated cycle oil.Type: GrantFiled: October 24, 2018Date of Patent: March 30, 2021Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPECInventors: Jianhong Gong, Zekun Li, Jinlian Tang, Anguo Mao, Jiushun Zhang, Yuying Zhang, Jun Long
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Patent number: 10808188Abstract: A catalytic cracking process includes the following steps: i) subjecting a heavy feedstock oil to flail catalytic cracking; ii) separating the catalytic cracking reaction product obtained from step i) to obtain a catalytic cracking gasoline and a catalytic cracking light cycle oil; iii) splitting the catalytic cracking gasoline to obtain a light gasoline fraction, a medium gasoline fraction and a heavy gasoline fraction; iv) subjecting the catalytic cracking light cycle oil to hydrogenation to obtain a hydrogenated light cycle oil); v) mixing a portion of the light gasoline fraction with at least a portion of the hydrogenated light cycle oil to obtain a mixed fraction; vi) subjecting the mixed fraction to catalytic cracking; and vii) subjecting a portion of the medium gasoline fraction to flail catalytic cracking. The process is capable of producing more catalytic cracking gasoline, reducing the olefin content of the catalytic cracking gasoline, and increasing its octane number.Type: GrantFiled: September 25, 2018Date of Patent: October 20, 2020Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPECInventors: Jianhong Gong, Zekun Li, Jinlian Tang, Anguo Mao, Jiushun Zhang, Yuying Zhang, Jun Long
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Publication number: 20200239791Abstract: Disclosed is a catalytic cracking process for producing isobutane and/or light aromatics in high yield, comprising the steps of: a) providing a catalytic cracking feedstock oil having a polycyclic naphthene content of greater than about 25 wt %; b) subjecting the catalytic cracking feedstock oil to a first catalytic cracking reaction and a second catalytic cracking reaction sequentially under different reaction conditions to obtain a catalytic cracking product; c) separating the resulting catalytic cracking product to obtain a liquefied gas fraction comprising isobutane and a gasoline fraction comprising light aromatics; and d) optionally, recovering isobutane from the liquefied gas fraction and/or recovering light aromatics from the gasoline fraction. The process can enable the production of isobutane and/or light aromatics in high yield.Type: ApplicationFiled: October 22, 2018Publication date: July 30, 2020Inventors: Youhao XU, Xin WANG, Yuying ZHANG, Tao LIU, Xuhui BAI, Lishun DAI, Zhigan ZHANG, Jialin LIANG, Nan JIANG
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Publication number: 20200147129Abstract: Provided are a method, target and application for NO accumulation to decrease invasiveness of Pseudomonas aeruginosa; achieving NO accumulation by means of external NO donors or disruption of internal NO metabolism in an environment where Pseudomonas aeruginosa is growing or being cultured, in order to decrease production by Pseudomonas aeruginosa of the invasion factor pyocyanin. Utilizing even micro-quantities of NO can significantly inhibit Pseudomonas aeruginosa PCN (PCN synthesis down 82% with 60 ?M SNP treatment); by inhibiting NO reductase, an enzyme related to NO metabolism, PCN synthesis can be significantly inhibited (the PAO1-?nor strain has 84% PCN reduction). Using NO donors or inhibiting enzymes involved in Pseudomonas aeruginosa NO metabolism as a means of combating bacterial infectious disease does not affect the body's normal microflora like traditional antibiotics.Type: ApplicationFiled: January 9, 2020Publication date: May 14, 2020Inventors: Yi WAN, Chang CHEN, Lei GAO, Yuying ZHANG, Xinhua QIAO, Yan WANG
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Publication number: 20200042522Abstract: Techniques are provided for gathering statistics in a database system. The techniques involve gathering some statistics using an “on-the-fly” technique, some statistics through a “high-frequency” technique, and yet other statistics using a “prediction” technique. The technique used to gather each statistic is based, at least in part, on the overhead required to gather the statistic. For example, low-overhead statistics may be gathered “on-the-fly” using the same process that is performing the operation that affects the statistic, while statistics whose gathering incurs greater overhead may be gathered in the background, while the database is live, using the high-frequency technique. The prediction technique may be used for relatively-high overhead statistics that can be predicted based on historical data and the current value of predictor statistics.Type: ApplicationFiled: August 6, 2019Publication date: February 6, 2020Inventors: Mohamed Zait, Yuying Zhang, Hong Su, Jiakun Li
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Patent number: 10537593Abstract: Provided are a method, target and application for NO accumulation to decrease invasiveness of Pseudomonas aeruginosa; achieving NO accumulation by means of external NO donors or disruption of internal NO metabolism in an environment where Pseudomonas aeruginosa is growing or being cultured, in order to decrease production by Pseudomonas aeruginosa of the invasion factor pyocyanin. Utilizing even micro-quantities of NO can significantly inhibit Pseudomonas aeruginosa PCN (PCN synthesis down 82% with 60 ?M SNP treatment); by inhibiting NO reductase, an enzyme related to NO metabolism, PCN synthesis can be significantly inhibited (the PAO1-?nor strain has 84% PCN reduction). Using NO donors or inhibiting enzymes involved in Pseudomonas aeruginosa NO metabolism as a means of combating bacterial infectious disease does not affect the body's normal microflora like traditional antibiotics.Type: GrantFiled: October 22, 2016Date of Patent: January 21, 2020Inventors: Yi Wan, Chang Chen, Lei Gao, Yuying Zhang, Xinhua Qiao, Yan Wang
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Publication number: 20190119586Abstract: The present disclosure relates to a process for producing catalytic cracking gasoline comprising the following steps: i) subjecting a heavy feedstock oil to a catalytic cracking reaction in the presence of a first catalytic cracking catalyst to obtain a first reaction product; ii) subjecting a hydrogenated cycle oil to a catalytic cracking reaction in the presence of a second catalytic cracking catalyst to obtain a second reaction product; iii) separating a mixture of the first reaction product and the second reaction product to obtain a catalytic cracking gasoline and a catalytic cracking light cycle oil; iv) subjecting the catalytic cracking light cycle oil or a fraction thereof to hydrogenation to obtain a hydrogenated product; and v) recycling the hydrogenated product to the step ii) as the hydrogenated cycle oil. The present disclosure also relates to a catalytic cracking system for carrying out the process.Type: ApplicationFiled: October 24, 2018Publication date: April 25, 2019Inventors: Jianhong GONG, Zekun LI, Jinlian TANG, Anguo MAO, Jiushun ZHANG, Yuying ZHANG, Jun LONG