Abstract: A thermoplastic multilayer article comprises: a polycarbonate substrate comprising a polycarbonate composition comprising at least one of a polycarbonate homopolymer, a copolycarbonate, or a polycarbonate copolymer, the polycarbonate substrate having a first surface and an opposing second surface; and a first polyurethane layer laminated or coextruded on at least a portion of the first surface of the polycarbonate substrate, the first polyurethane layer comprising a first aliphatic thermoplastic polyurethane and a polyurethane UV stabilizer, wherein the first aliphatic thermoplastic polyurethane comprises first segments formed via a reaction of caprolactone and an aliphatic isocyanate, and second segments formed via a reaction of a chain extender and the aliphatic isocyanate.

Abstract: Disclosed herein is a system and a computer implemented method for managing associations between a plurality of entities in a safe, reliable, effective and efficient manner. The system leverages biometric authentication and identity verification to ensure authentic entity profiles and weed out fake profiles and transactions. Further, the system employs one or more artificial intelligence based algorithms to generate an integrity score for a registered entity based on veracity of information shared by an entity with other entities and with the platform, thereby eliminating fake claims made by registered entities to solicit proposals and connection requests.

Abstract: A thermoplastic multilayer article comprises: a polycarbonate substrate comprising a polycarbonate composition comprising at least one of a polycarbonate homopolymer, a copolycarbonate, or a polycarbonate copolymer, the polycarbonate substrate having a first surface and an opposing second surface; and a first polyurethane layer laminated or coextruded on at least a portion of the first surface of the polycarbonate substrate, the first polyurethane layer comprising a first aliphatic thermoplastic polyurethane and a polyurethane UV stabilizer, wherein the first aliphatic thermoplastic polyurethane comprises first segments formed via a reaction of caprolactone and an aliphatic isocyanate, and second segments formed via a reaction of a chain extender and the aliphatic isocyanate.

Abstract: A lurasidone solid dispersion and a preparation method thereof. The solid dispersion includes a mixture of lurasidone, a pharmaceutical carrier and a plasticizer, in which the lurasidone is in a free base form. The lurasidone solid dispersion obtained by the preparation method has characteristics of high dissolution rate (over 30%) in partial neutral medium (such as pH 6.0), significantly increased bioavailability, and significantly reduced food effect, which overcomes the excessive medication limitation in the prior art, avoids the reduction or even inefficiency of the curative effect caused by improper medication of patients, ensures the normal exertion of the medication effect, thereby increases the flexibility and compliance of patients to take medicine.

Abstract: It relates to a lurasidone solid dispersion and a preparation method, wherein the method comprises melting treatment of a mixture containing lurasidone, a medicinal hot melt carrier, optionally an acidic regulator and plasticizer in order to obtain the solid dispersion described herein, and wherein the lurasidone is provided in a form of free base. The lurasidone solid dispersion obtained by the preparation method according to the example of the invention has the characteristics of high dissolution rate (dissolution rate can reach 30%-70%) in a partial neutral medium (e.g. pH6.0). The bioavailability of lurasidone solid dispersion increased significantly and the food effect of lurasidone solid dispersion prepared from the example decreased remarkably.

Abstract: Disclosed herein is a system and a computer implemented method for managing associations between a plurality of entities in a safe, reliable, effective and efficient manner. The system leverages biometric authentication and identity verification to ensure authentic entity profiles and weed out fake profiles and transactions. Further, the system employs one or more artificial intelligence based algorithms to generate an integrity score for a registered entity based on veracity of information shared by an entity with other entities and with the platform, thereby eliminating fake claims made by registered entities to solicit proposals and connection requests.

Abstract: A method of thermoforming an article from an integrated transparent conductive film, comprising: applying an ultraviolet curable transfer coating to a first surface of a recipient substrate or to a first surface of a donor substrate, wherein the first surface of the donor substrate includes a conductive coating coupled thereto; pressing the first surface of the recipient substrate and the first surface of the donor substrate together to form a stack; heating the stack and activating the ultraviolet curable transfer coating with an ultraviolet radiation source; removing the donor substrate from the stack leaving a transparent conductive layer, wherein the ultraviolet curable transfer coating remains adhered to the first surface of the recipient substrate and to the conductive coating; laser etching an electrical circuit onto a transparent conductive layer second surface to form an integrated transparent conductive film; and thermoforming the integrated transparent conductive film to form the article.

Abstract: A thermoplastic composition, comprising, based on the total weight of the composition: 15 to 90 weight percent of a first poly(aliphatic ester-carbonate) having a first weight average molecular weight; 10 to 85 weight percent of a second poly(aliphatic ester-carbonate) having a second weight average molecular weight that is lower than the first weight average molecular weight; 0.01 to 0.5 weight percent of a mold release agent; 0.01 to 0.5 weight percent of a thermal stabilizer; 0.01 to 0.5 weight percent of a chain extender; San average melt volume flow rate of less than 40 cubic centimeters per 10 minutes when measured at 300° C. at a shear load of 1.2 kg, and an average melt volume flow rate of less than 40 cubic centimeters per 10 minutes when measured at 250° C. at a shear load of 5.0 kg.

Abstract: It relates to a lurasidone solid dispersion and a preparation method, wherein the method comprises melting treatment of a mixture containing lurasidone, a medicinal hot melt carrier, optionally an acidic regulator and plasticizer in order to obtain the solid dispersion described herein, and wherein the lurasidone is provided in a form of free base. The lurasidone solid dispersion obtained by the preparation method according to the example of the invention has the characteristics of high dissolution rate (dissolution rate can reach 30%-70%) in a partial neutral medium (e.g. pH6.0). The bioavailability of lurasidone solid dispersion increased significantly and the food effect of lurasidone solid dispersion prepared from the example decreased remarkably.

Abstract: A method of forming an article of manufacture, comprising: forming a mold insert, comprising applying a conductive layer on a donor substrate second surface, wherein the conductive layer includes nanometer sized metal particles arranged in a network; applying an ultraviolet curable coating layer to a recipient substrate first surface; pressing the recipient substrate, the ultraviolet curable coating layer, and the donor substrate together to form a stack; heating the stack and activating the ultraviolet cured coating layer with an ultraviolet radiation source; removing the donor substrate from the stack, wherein the ultraviolet curable coating layer adheres to the recipient substrate first surface and the conductive layer; thermoforming the mold insert; and injection molding a polymeric resin layer around a portion of the recipient substrate second surface.

Abstract: Provided herein are test elements useful in medical applications, such as glucose testing strips. The test elements have improved mechanical properties and improved processing characteristics as compared to existing test elements.

Abstract: A method of making a multilayer sheet includes: forming a substrate including a substrate first surface and a substrate second surface; applying a conductive layer including a base and a conductive coating to the substrate first surface; and applying an ultraviolet cured coating layer to a surface of the conductive layer opposite that in contact with the substrate second surface, wherein the ultraviolet cured coating layer comprises a multifunctional acrylate oligomer and an acrylate monomer; pressing the substrate, conductive layer, and ultraviolet cured coating layer together to form a stack; heating the stack; activating the ultraviolet cured coating layer with an ultraviolet radiation source; and removing the base from the stack leaving a conductive multilayer sheet; wherein the ultraviolet cured coating layer remains adhered to the conductive layer.

Abstract: A method of thermoforming an article from an integrated transparent conductive film includes heating the integrated transparent conductive film to a formable temperature in a mold, wherein the integrated transparent conductive film comprises a substrate comprising a transparent thermoplastic material, wherein the substrate includes a substrate first surface and a substrate second surface; a transparent conductive layer disposed adjacent to the substrate, wherein the transparent conductive layer includes a transparent conductive layer first surfaced disposed on the substrate first surface; and an electrical circuit etched onto a transparent conductive layer second surface; thermoforming the integrated transparent conductive film to the article comprising the mold shape; cooling the formed article; and removing the formed article form the mold; wherein the formed article has a functional electrical circuit after thermoforming.

Abstract: A method of making a multilayer sheet includes: forming a substrate including a substrate first surface and a substrate second surface; applying a conductive layer including a base and a conductive coating to the substrate first surface; and applying an ultraviolet cured coating layer to a surface of the conductive layer opposite that in contact with the substrate second surface, wherein the ultraviolet cured coating layer comprises a multifunctional acrylate oligomer and an acrylate monomer; pressing the substrate, conductive layer, and ultraviolet cured coating layer together to form a stack; heating the stack; activating the ultraviolet cured coating layer with an ultraviolet radiation source; and removing the base from the stack leaving a conductive multilayer sheet; wherein the ultraviolet cured coating layer remains adhered to the conductive layer.

Abstract: An integrated conductive film can comprise: a first substrate including a first surface and a second surface, wherein the first substrate comprises a first polymer; a second substrate coupled to the second surface of the first substrate, wherein the second substrate comprises a second polymer, and wherein the chemical composition of the first polymer is different from the chemical composition of the second polymer; a transfer resin disposed adjacent to the first surface of the first substrate; a conductive coating disposed adjacent to the transfer resin, and wherein a change in electrical resistance of the integrated conductive film is less than or equal to 1 ohm when the film is bent to a bend radius of less than or equal to 126 millimeters as per ASTM D5023.

Abstract: An ultraviolet curable transfer coating can comprise: a multifunctional acrylate oligomer; an acrylate monomer; and a photoinitiator; wherein the ultraviolet curable transfer coating includes a total weight, wherein 30% to 80% of the total weight comprises the multifunctional acrylate oligomer, wherein 15% to 65% of the total weight comprises the acrylate monomer, and wherein 3% to 7% of the total weight comprises the photoinitiator.

Abstract: Described herein is a thermoplastic composition comprising a polycarbonate, a mineral filler, inorganic acid or acid salt, an anti-drip agent, and a flame retardant comprising a perfluoroalkyl sulfonate salt or a combination of an aromatic phosphate ester and a polycarbonate-siloxane block copolymer.

Abstract: A polycarbonate film having a thickness of 0.05 mm to 0.25 mm is formed from a thermoplastic composition that includes a first branched polycarbonate that has a peak melt viscosity of at least 7,000 poise when measured using a parallel plate melt rheology test at a heating rate of 10° C./min at a temperature of between 350° C. to 450° C., a second branched polycarbonate, and a perfluoroalkyl sulfonate salt.

Abstract: Disclosed herein is a flame retardant composition comprising 10 to 90 weight percent of a linear polycarbonate; a branched polycarbonate; 10 to 70 weight percent of a polysiloxane-polycarbonate copolymer; and 1 to 20 weight percent of a phosphazene compound; were all weight percents are based on the total weight of the composition. Disclosed herein too is a method comprising blending 10 to 90 weight percent of a linear polycarbonate; a branched polycarbonate; 10 to 70 weight percent of a polysiloxane-polycarbonate copolymer; and 1 to 20 weight percent of a phosphazene compound; to form a flame retardant composition; were all weight percents are based on the total weight of the composition.

Abstract: Disclosed herein is a flame retardant composition comprising 10 to 90 weight percent of a linear polycarbonate; 5 to 50 weight percent of a polysiloxane-polycarbonate copolymer; where the polysiloxane-polycarbonate copolymer comprises 10 weight percent or more of polysiloxane and where the molecular weight of the polysiloxane is 30,000 grams per mole or greater; and 1 to 20 weight percent of a phosphazene compound; where all weight percents are based on the total weight of the composition.