Abstract: A vehicle door structure is disclosed which includes a door equipped with a door frame. The door frame has a door glass run at an inner peripheral portion which functions to seal a passenger compartment from the exterior of the vehicle. The door glass run comprises an inner lip and an outer lip. The inner lip is in contact with an interior surface of a door glass, and the outer lip is in contact with an exterior surface of the door glass. The outer lip has an inclined tip portion and a prop portion. The inclined tip portion is in contact with the exterior surface of the door glass, and the prop portion can sustain the door glass when it is biased toward the exterior of the door by force generated by a difference in pressure between the passenger compartment and the exterior surface of the door when a vehicle runs at a high speed.