Patents by Inventor Yuzo Takayama

Yuzo Takayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing parasympathetic neurons
    Patent number: 11359178
    Abstract: The present invention provides a method for producing parasympathetic neurons from neural crest cells or autonomic neural progenitor cells derived therefrom, comprising a step of culturing the neural crest cells or autonomic neural progenitor cells derived therefrom in the presence of a cAMP production promoter, a BDNF signaling pathway activator, a GDNF signaling pathway activator, an NGF signaling pathway activator, an NT-3 signaling pathway activator, vitamin C, a protein kinase C activator, and a retinoic acid receptor agonist.
    Type: Grant
    Filed: August 23, 2019
    Date of Patent: June 14, 2022
    Assignee: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Yuzo Takayama, Yasuyuki Kida
  • Method for inducing differentiation of neural crest cells into neurons of the autonomic nervous system
    Patent number: 11186821
    Abstract: Provided is a method for inducing differentiation of neural crest cells into neurons of the autonomic nervous system, the method including the step of culturing neural crest cells in the presence of at least one of a BMP signaling pathway activator, an SHH signaling pathway inhibitor, and a Wnt signaling pathway inhibitor.
    Type: Grant
    Filed: April 26, 2016
    Date of Patent: November 30, 2021
    Assignee: National Institute of Advanced Industrial Science and Technology
    Inventors: Yasuyuki Kida, Yuzo Takayama
  • METHOD FOR PRODUCING PARASYMPATHETIC NEURONS
    Publication number: 20210171905
    Abstract: The present invention provides a method for producing parasympathetic neurons from neural crest cells or autonomic neural progenitor cells derived therefrom, comprising a step of culturing the neural crest cells or autonomic neural progenitor cells derived therefrom in the presence of a cAMP production promoter, a BDNF signaling pathway activator, a GDNF signaling pathway activator, an NGF signaling pathway activator, an NT-3 signaling pathway activator, vitamin C, a protein kinase C activator, and a retinoic acid receptor agonist.
    Type: Application
    Filed: August 23, 2019
    Publication date: June 10, 2021
    Inventors: Yuzo Takayama, Yasuyuki Kida
  • METHOD FOR INDUCING DIFFERENTIATION OF NEURAL CREST CELLS INTO NEURONS OF THE AUTONOMIC NERVOUS SYSTEM
    Publication number: 20180155682
    Abstract: Provided is a method for inducing differentiation of neural crest cells into neurons of the autonomic nervous system, the method including the step of culturing neural crest cells in the presence of at least one of a BMP signaling pathway activator, an SHH signaling pathway inhibitor, and a Wnt signaling pathway inhibitor.
    Type: Application
    Filed: April 26, 2016
    Publication date: June 7, 2018
    Inventors: Yasuyuki Kida, Yuzo Takayama