Patents by Inventor Yuzuru Kubohara

Yuzuru Kubohara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amide derivative
    Patent number: 11040937
    Abstract: The present invention provides a useful medicament for the treatment and/or prophylaxis of a disease associated with the enhancement of OPN production including cancer, which comprises a compound of formula: wherein R1, R2, R3, R4, R5, R6, R7, m, n, p, X, and Y are as defined in the specification, a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: June 22, 2021
    Assignees: TOHOKU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY, FUSO PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Haruhisa Kikuchi, Yoshiteru Oshima, Toshio Hattori, Yuzuru Kubohara, Osamu Yamada, Jing Zhang, Yoshihisa Matsushita, Shinya Kida
  • AMIDE DERIVATIVE
    Publication number: 20160368860
    Abstract: The present invention provides a useful medicament for the treatment and/or prophylaxis of a disease associated with the enhancement of OPN production including cancer, which comprises a compound of formula: wherein R1, R2, R3, R4, R5, R6, R7, m, n, p, X, and Y are as defined in the specification, a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 27, 2015
    Publication date: December 22, 2016
    Inventors: Haruhisa Kikuchi, Yoshiteru Oshima, Toshio Hattori, Yuzuru Kubohara, Osamu Yamada, Jing Zhang, Yoshihisa Matsushita, Shinya Kida
  • Osteopontin production inhibitor containing dictyopyrone derivative or dihydrodictyopyrone derivative as active ingredient
    Patent number: 9463188
    Abstract: Disclosed herein is an osteopontin production inhibitor capable of preventing a disease resulting from increased production of osteopontin. The osteopontin production inhibitor contains a dictyopyrone derivative or a dihydrodictyopyrone derivative as an active ingredient. The dictyopyrone derivative is preferably a compound represented by Chemical Formula 1 or 2, and the dihydrodictyopyrone derivative is preferably a compound represented by Chemical Formula 3 or 4.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: October 11, 2016
    Assignees: TOHOKU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY, FUSO PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Haruhisa Kikuchi, Yoshiteru Oshima, Toshio Hattori, Yuzuru Kubohara, Osamu Yamada, Jing Zhang, Yoshihisa Matsushita, Shinya Kida
  • OSTEOPONTIN PRODUCTION INHIBITOR CONTAINING DICTYOPYRONE DERIVATIVE OR DIHYDRODICTYOPYRONE DERIVATIVE AS ACTIVE INGREDIENT
    Publication number: 20150366851
    Abstract: Disclosed herein is an osteopontin production inhibitor capable of preventing a disease resulting from increased production of osteopontin. The osteopontin production inhibitor contains a dictyopyrone derivative or a dihydrodictyopyrone derivative as an active ingredient. The dictyopyrone derivative is preferably a compound represented by Chemical Formula 1 or 2, and the dihydrodictyopyrone derivative is preferably a compound represented by Chemical Formula 3 or 4.
    Type: Application
    Filed: November 26, 2013
    Publication date: December 24, 2015
    Applicants: TOHOKU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY, FUSO PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Haruhisa Kikuchi, Yoshiteru Oshima, Toshio Hattori, Yuzuru Kubohara, Osamu Yamada, Jing Zhang, Yoshihisa Matsushita, Shinya Kida
  • Method of lowering blood glucose and method of treating diabetes and obesity
    Patent number: 7846974
    Abstract: The compound represented by the general formula (I) is administered to a subject suffering from diabetes or obesity. In the formula (I), R1 and R2 independently represent an aliphatic hydrocarbon group having 1 to 10 carbon atoms or phenyl group, and arbitrary hydrogen atoms on the aliphatic hydrocarbon group and the phenyl group may be replaced by halogen, X1 represents halogen, and X2 represents hydrogen or halogen.
    Type: Grant
    Filed: October 24, 2007
    Date of Patent: December 7, 2010
    Assignee: National University Corporation Gunma University
    Inventors: Yuzuru Kubohara, Hiroshi Shibata
  • METHOD OF LOWERING BLOOD GLUCOSE AND METHOD OF PREVENTING OR TREATING BLOOD GLUCOSE AND METHOD OF PREVENTING OR TREATING DIABETES AND OBESITY
    Publication number: 20090111893
    Abstract: The compound represented by the general formula (I) is administered to a subject suffering from diabetes or obesity. In the formula (I), R1 and R2 independently represent an aliphatic hydrocarbon group having 1 to 10 carbon atoms or phenyl group, and arbitrary hydrogen atoms on the aliphatic hydrocarbon group and the phenyl group may be replaced by halogen, X1 represents halogen, and X2 represents hydrogen or halogen.
    Type: Application
    Filed: October 24, 2007
    Publication date: April 30, 2009
    Applicant: National University Corporation Gunma University
    Inventors: Yuzuru Kubohara, Hiroshi Shibata