Patents by Inventor Yvan Huerou

Yvan Huerou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thioalkeneamides as Transketolase Inhibitors
    Publication number: 20070293501
    Abstract: The present invention provides thioalkeneamides of formula (I) which are useful as transketolase inhibitors: wherein R1, R2, R3, R4, R5, R6, Ra-Rd, n and ring A are as defined herein. The present invention also provides pharmaceutical compositions comprising the compounds of formula (I). The invention provides methods for inhibiting transketolase activity, reducing cellular ribose-5-phosphate levels, inhibiting nucleic acid synthesis, inhibiting cell proliferation and tumor cell growth in vitro and in vivo, stimulating apoptosis in tumor cells and treating cancer by administering a compound of formula (I) or a pharmaceutical composition thereof.
    Type: Application
    Filed: March 23, 2005
    Publication date: December 20, 2007
    Applicant: ARRAY BIOPHARMA INC.
    Inventors: Steven Boyd, Kevin Condroski, Allen Thomas, Stephen Gonzales, Indrani Gunawardana, Yvan Huerou, Todd Romoff, Francis Sullivan