Abstract: A method for modifying the value of an electrical resistance (30), comprising a ferromagnetic material (31) having a first magnetization direction, comprising the following steps of: illuminating, by a first LASER beam (14), a first area (32) of the ferromagnetic material (31), so that this area is heated at a temperature equal to or higher than the Curie temperature of the ferromagnetic material (31); applying in the first area (32) a first magnetic field having a direction opposite to the first magnetization direction of the ferromagnetic material (31); reducing the energy brought by the first LASER beam (14) to the first area (32) in order to enable the first area to be cooled to form a first controlled magnetic domain (36C).

Abstract: The invention concerns molecules with a bis-(heteroaryl)maleimide structure and having inhibiting characteristics with respect to enzymes with a catalytic pocket comprising the invariant amino acids D, D and E or D, D and D, such as transposases, RAG recombinases or retroviral integrases. The invention also concerns the use of said molecules for in vitro, ex vivo or in vivo inhibition of transposases, RAG recombinases and retroviral integrases such as HIV integrase, as well as the use of said molecules in the treatment of diseases associated with these enzymes in an animal or human host, in particular in the treatment of AIDS.

Abstract: The invention relates to hyperactive, non-phosphorylated, mutant transposases of mariner mobile genetic elements. The invention also relates to recombinant nucleotide sequences encoding such transposases. The invention further relates to a method of producing said transposases and to the use thereof for in vitro or in vivo transposition.

Abstract: The present invention relates to a process for the production, by a prokaryotic host cell, of an active, stable transposase of a Mariner mobile genetic element belonging to the mauritiana subfamily. The invention also relates to an active, stable transposase that can be produced using such a process, and to the molecular biology tools, such as the prokaryotic host cells, the expression vectors or the kits, which make it possible to produce an active, stable transposase, or which use it. In addition, the present invention relates to the uses of the active, stable transposases.

Abstract: The invention relates to hyperactive, non-phosphorylated, mutant transposases of mariner mobile genetic elements. The invention also relates to recombinant nucleotide sequences encoding such transposases. The invention further relates to a method of producing said transposases and to the use thereof for in vitro or in vivo transposition.

Abstract: Low-vulnerability component of explosive ammunition and process for initiating a charge of low-sensitivity composite explosive. The subject of the present invention is a low-vulnerability component of explosive ammunition consisting of a preferably metallic enclosure 1 containing a charge 2 of low-sensitivity composite explosive E and, as initiating relay, a plane wave generator 3 consisting, on the one hand, of a cylindroconical cap 7 made of composite explosive A, the large base surface having a diameter d greater than the critical diameter of the explosive E, the cavity 8 of this cap 7 being filled with a composite explosive B and, on the other hand, of a reinforcer made of composite explosive C, of thickness e greater than 0.1 d, the detonation pressure of the explosive C being higher than that of the explosive E.