Abstract: A powder sterilization method for sterilizing powder, in particular an active pharmaceutical ingredient in powder form or food in powder form, using fluid vapor, in particular steam. According to the invention, the fluid vapor is applied to the powder in an evacuated treatment chamber (3), in particular it is applied to the powder during its free fall along a drop section (7), in particular in countercurrent.

Abstract: A powder sterilization method for sterilizing powder, in particular an active pharmaceutical ingredient in powder form or food in powder form, using fluid vapor, in particular steam. According to the invention, the fluid vapor is applied to the powder in an evacuated treatment chamber (3), in particular it is applied to the powder during its free fall along a drop section (7), in particular in countercurrent.

Abstract: The present invention relates to a short cell penetrating peptide derived from the Epstein-Barr virus basic leucine zipper transcriptional activator (ZEBRA), optionally linked to a cargo molecule. It also relates to a complex comprising the cell penetrating peptide and a cargo molecule, as well as cells loaded with the complex and the use thereof in therapy and diagnosis.

Abstract: The present invention relates to isolated polypeptides comprising: (i) a protein transduction domain consisting of ZEBRA or a fragment thereof that retains the capacity of internalization, (ii) at least one CD4+ epitope; and (iii) at least one CD8+ epitope. It also relates to antigen presenting cells loaded with said polypeptides, and the use thereof in immunotherapy including prevention and/or treatment of cancers or infectious diseases.

Abstract: The present invention relates to isolated polypeptides comprising: (i) a protein transduction domain consisting of ZEBRA or a fragment thereof that retains the capacity of internalization, (ii) at least one CD4+ epitope; and (iii) at least one CD8+ epitope. It also relates to antigen presenting cells loaded with said polypeptides, and the use thereof in immunotherapy including prevention and/or treatment of cancers or infectious diseases.

Abstract: The present invention relates to a short cell penetrating peptide derived from ZEBRA, optionally linked to a cargo molecule. It also relates to a complex comprising said cell penetrating peptide and a cargo molecule, as well as cells loaded with said complex and the use thereof in therapy and diagnosis.

Abstract: A device for pneumatic treatment of powder materials in a recipient chamber (22), with introduction of two material streams into the above through two inlet tubes (40, 40a), optionally in a counter-current and/or approximately tangential sense and swirled in the recipient chamber (22). The material streams are for introduction at roughly the same level in the container and the tracks thereof are interleaved. The material streams are also introduced at an inclination angle (w) to a radial plane (E) of the recipient chamber (22) which is inclined downwards.

Abstract: The present invention relates to isolated polypeptides comprising: (i) a protein transduction domain consisting of ZEBRA or a fragment thereof that retains the capacity of internalization, (ii) at least one CD4+ epitope; and (iii) at least one CD8+ epitope. It also relates to antigen presenting cells loaded with said polypeptides, and the use thereof in immunotherapy including prevention and/or treatment of cancers or infectious diseases.

Abstract: The present invention relates to the use of a compound that specifically binds to JAM-C or JAM-B for the treatment of gliomas. More specifically the invention relates to the use of an antagonist of JAM-B or JAM-C for the treatment of glioma, in particular astrocytoma.

Abstract: The present invention relates to the use of a compound that specifically binds to JAM-C or JAM-B for the treatment of gliomas. More specifically the invention relates to the use of an antagonist of JAM-B or JAM-C for the treatment of glioma, in particular astrocytoma.

Abstract: The invention relates to a method for pneumatic treatment of powder materials in a recipient chamber (22), with introduction of two material streams into the above through two inlet tubes (40, 40a), optionally in a counter-current and/or approximately tangential sense and swirled in the recipient chamber (22). The material streams are for introduction at roughly the same level in the container and the tracks thereof are interleaved. The material streams are also introduced at an inclination angle (w) to a radial plane (E) of the recipient chamber (22) which is inclined downwards.

Abstract: An apparatus for decanting pulverulent product (Q) into a receptacle (50) made of deformable material which receptacle is arranged in a container made of rigid material and is temporarily placed upstream of a lock system containing so-called glove boxes, a shaft (64) is rotatably mounted at a distance (n) from an adjustable base (B), on which shaft at least one hood designed as a glove box, at least one hood trough (80) made of metallic material, preferably of stainless steel, is fixed; at least one support plate (78) for the rigid container is attached to length-adjustable piston/cylinder units (76) at an adjustable distance from the shaft (64), the support plate being parallel to the shaft longitudinal axis (N), and the rigid container is sealingly connected at the other end to a connecting tube (34a) which projects into the hood or the hood trough (80) or the hood system.

Abstract: The invention relates to a device for suctioning a powdery product. Said device comprises a auctioning tube (1,1?) which can be connected to a pneumatic suction transfer system and a clod-breaking device comprising a worm conveyor (4) which is rotationally driven by a motor (10) via a shaft (7). The worm conveyor is located at the end of the auctioning device in a truncated housing (3). The blades of the worm conveyor are provided with teeth and the shaft (7) is provided with knives (8) downstream from the worm conveyor (4). Any clods can be broken up by the worm conveyor (4) and the knives (8) complete the work of the worm conveyor by breaking up any clusters which move beyond the worm conveyor (4).

Abstract: An apparatus for decanting pulverulent product (Q) into a receptacle (50) made of deformable material which receptacle is arranged in a container made of rigid material and is temporarily placed upstream of a lock system containing so-called glove boxes, a shaft (64) is rotatably mounted at a distance (n) from an adjustable base (B), on which shaft at least one hood designed as a glove box, at least one hood trough (80) made of metallic material, preferably of stainless steel, is fixed; at least one support plate (78) for the rigid container is attached to length-adjustable piston/cylinder units (76) at an adjustable distance from the shaft (64), the support plate being parallel to the shaft longitudinal axis (N), and the rigid container is sealingly connected at the other end to a connecting tube (34a) which projects into the hood or the hood trough (80) or the hood system.