Patents by Inventor Yves Meyvis

Yves Meyvis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR THE PRODUCTION OF IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS
    Publication number: 20200392214
    Abstract: The present invention relates to an improved method for the manufacture of immunoglobulin single variable domains. More specifically, the present invention relates to a method of producing immunoglobulin single variable domains in which the proportion of carbamylated variants is strongly reduced or absent and to improved immunoglobulin single variable domains obtainable by methods of the present invention.
    Type: Application
    Filed: August 2, 2019
    Publication date: December 17, 2020
    Applicant: Ablynx N.V.
    Inventors: Ann Brige, Bart Walcarius, Yves Meyvis, Mauro Sergi
  • METHOD FOR THE PRODUCTION OF IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS
    Publication number: 20200062834
    Abstract: The present invention relates to an improved method for the manufacture of immunoglobulin single variable domains. More specifically, the present invention relates to a method of producing immunoglobulin single variable domains in which the proportion of carbamylated variants is strongly reduced or absent and to improved immunoglobulin single variable domains obtainable by methods of the present invention.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 27, 2020
    Applicant: Ablynx N.V.
    Inventors: Ann Brige, Bart Walcarius, Yves Meyvis, Mauro Sergi
  • STABLE FORMULATIONS OF IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS
    Publication number: 20190010249
    Abstract: The present invention relates to stable formulations of polypeptides, e.g. immunoglobulin single variable domains, in particular immunoglobulin single variable domains directed against von Willebrand Factor (vWF). The invention provides formulations which are stable upon storage for prolonged periods of time and over a broad range of temperatures. The formulations of the invention ensure a high stability of the polypeptide, allowing multiple freeze-thaw cycles without chemical or physical deterioration, and provide stability in relation to mechanical stress, such as shake, shear or stir stress. They are suitable for pharmaceutical and diagnostic preparations and compatible with pharmaceutically acceptable diluents.
    Type: Application
    Filed: June 14, 2018
    Publication date: January 10, 2019
    Applicant: Ablynx N.V.
    Inventors: YVES MEYVIS, Veronique De Brabandere, Hans Ulrichts, Ann Brige, Filip Callewaert
  • Stable formulations of immunoglobulin single variable domains
    Patent number: 10035862
    Abstract: The present invention relates to stable formulations of polypeptides, e.g. immunoglobulin single variable domains, in particular immunoglobulin single variable domains directed against von Willebrand Factor (vWF). The invention provides formulations which are stable upon storage for prolonged periods of time and over a broad range of temperatures. The formulations of the invention ensure a high stability of the polypeptide, allowing multiple freeze-thaw cycles without chemical or physical deterioration, and provide stability in relation to mechanical stress, such as shake, shear or stir stress. They are suitable for pharmaceutical and diagnostic preparations and compatible with pharmaceutically acceptable diluents.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: July 31, 2018
    Assignee: Ablynx N.V.
    Inventors: Yves Meyvis, Veronique De Brabandere, Hans Ulrichts, Ann Brige, Filip Callewaert
  • STABLE FORMULATIONS OF IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS AND USES THEREOF
    Publication number: 20160090424
    Abstract: The present invention relates to stable formulations of polypeptides, e.g. immunoglobulin single variable domains, in particular immunoglobulin single variable domains directed against von Willebrand Factor (vWF). The invention provides formulations which are stable upon storage for prolonged periods of time and over a broad range of temperatures. The formulations of the invention ensure a high stability of the polypeptide, allowing multiple freeze-thaw cycles without chemical or physical deterioration, and provide stability in relation to mechanical stress, such as shake, shear or stir stress. They are suitable for pharmaceutical and diagnostic preparations and compatible with pharmaceutically acceptable diluents.
    Type: Application
    Filed: May 16, 2014
    Publication date: March 31, 2016
    Applicant: Ablynx N.V.
    Inventors: Yves Meyvis, Veronique De Brabandere, Hans Ulrichts, Ann Brige, Filip Callewaert
  • METHOD FOR THE PRODUCTION OF IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS
    Publication number: 20130261288
    Abstract: The present disclosure relates to an improved method for the manufacture of immunoglobulin single variable domains. More specifically, the present disclosure relates to a method of producing immunoglobulin single variable domains in which the proportion of carbamylated variants is strongly reduced or absent and to improved immunoglobulin single variable domains obtainable by methods of the present disclosure.
    Type: Application
    Filed: October 28, 2011
    Publication date: October 3, 2013
    Applicant: ABLYNX N.V.
    Inventors: Ann Brige, Bart Walcarius, Yves Meyvis, Mauro Sergi
  • STABLE FORMULATIONS OF IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS AND USES THEREOF
    Publication number: 20120225072
    Abstract: The present invention relates to stable formulations of polypeptides, e.g. immunoglobulin single variable domains.
    Type: Application
    Filed: March 1, 2012
    Publication date: September 6, 2012
    Applicant: Ablynx N.V.
    Inventors: Yves Meyvis, Ann Brige