Patents by Inventor Yves Poitevin

Yves Poitevin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR OPTIMIZING THE ASSEMBLY AND PRODUCTION OF HETERO-MULTIMERIC PROTEIN COMPLEXES
    Publication number: 20190226001
    Abstract: Methods are provided to improve the expression of protein complexes by tuning the expression levels of each component required for the assembly of the complex. These methods are effective in limiting the expression of the dominant chain and, thus, equilibrating their relative abundance. The methods provided herein lead to a significant increase in productivity and final bispecific yields both in transient expression systems as well as in stably transfected mammalian cells.
    Type: Application
    Filed: September 28, 2018
    Publication date: July 25, 2019
    Inventors: Giovanni MAGISTRELLI, Pauline MALINGE, Yves POITEVIN, Nicolas FISCHER
  • Method for optimizing the assembly and production of hetero-multimeric protein complexes
    Patent number: 10113193
    Abstract: Methods are provided to improve the expression of protein complexes by tuning the expression levels of each component required for the assembly of the complex. These methods are effective in limiting the expression of the dominant chain and, thus, equilibrating their relative abundance. The methods provided herein lead to a significant increase in productivity and final bispecific yields both in transient expression systems as well as in stably transfected mammalian cells.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: October 30, 2018
    Assignee: NovImmune SA
    Inventors: Giovanni Magistrelli, Pauline Malinge, Yves Poitevin, Nicolas Fischer
  • METHOD FOR OPTIMIZING THE ASSEMBLY AND PRODUCTION OF HETERO-MULTIMERIC PROTEIN COMPLEXES
    Publication number: 20160289727
    Abstract: Methods are provided to improve the expression of protein complexes by tuning the expression levels of each component required for the assembly of the complex. These methods are effective in limiting the expression of the dominant chain and, thus, equilibrating their relative abundance. The methods provided herein lead to a significant increase in productivity and final bispecific yields both in transient expression systems as well as in stably transfected mammalian cells.
    Type: Application
    Filed: March 31, 2016
    Publication date: October 6, 2016
    Inventors: Giovanni Magistrelli, Pauline Malinge, Yves Poitevin, Nicolas Fischer
  • IL-17 Mediated Transfection Methods
    Publication number: 20100093087
    Abstract: The invention comprises compositions and methods for IL-17-mediated transfection that results in superior and enhanced properties of cell survival and protein production.
    Type: Application
    Filed: October 7, 2009
    Publication date: April 15, 2010
    Applicant: Novlmmune S.A.
    Inventors: Greg Elson, Mathias Contie, Nicolas Fouque, Olivier Leger, Yves Poitevin